The CLEARSTEM MINDBODYSKIN Hormonal Acne Supplement is a daily internal supplement from CLEARSTEM designed to address the root causes of hormonal and cystic acne rather than reacting to breakouts after they appear. Instead of working on the surface, this formula supports the five internal systems most responsible for driving breakouts: hormone metabolism, liver detoxification, digestion, stress response, and excess oil production. It is available in two versions, one with 5-HTP and one without, so you can match the formula to your specific health picture.

Key Benefits

Healthier Estrogen Metabolism DIM (3,3'-diindolylmethane) helps shift estrogen breakdown toward less inflammatory pathways, directly reducing the hormonal signaling behind chin, jawline, and cystic breakouts.

Liver Support That Clears Hormones from the Body The Proprietary Liver Blend of milk thistle, dandelion root extract, and L-glutathione helps the liver process and clear excess hormones and metabolic waste before they recirculate and trigger new breakouts.

Fewer Stress-Driven Flares Pantothenic acid (vitamin B5) supports adrenal function and helps moderate the stress response, while 5-HTP (in the 5-HTP formula) promotes serotonin production to reduce cortisol-driven inflammation that spikes acne activity.

A Gut Environment Less Likely to Inflame Skin The Proprietary Digestive Blend of protease and betaine hydrochloride helps optimize stomach acid levels and protein digestion, supporting a gut environment that is less prone to the bacterial imbalances linked to acne flares.

Sebum Regulation at the Source Vitamin A and vitamin B5 work together to help moderate sebum production, targeting one of the core physiological reasons pores become congested and breakouts form.

If your breakouts tend to cluster around the chin, jawline, or cheeks and flare predictably around your cycle, the CLEARSTEM MINDBODYSKIN Hormonal Acne Supplement was built with your skin in mind. It is also a strong fit for anyone whose acne seems connected to stress, digestive irregularities, or sluggish detoxification rather than surface-level congestion alone.

This supplement comes in two versions. The standard formula includes 5-HTP, which supports serotonin production and is well-suited for people whose acne is triggered or worsened by stress and mood fluctuations. The No 5-HTP formula delivers the same core hormone, liver, and digestive support without that ingredient, and is the better choice for anyone currently taking an SSRI, antidepressant, or other serotonin-affecting medication.

This is not a spot treatment or a short-term fix. It is designed for consistent daily use as part of a broader approach to clearing skin from within. If you are unsure which formula fits your situation, a free skincare consultation with one of our licensed estheticians can help you decide.

Give the CLEARSTEM MINDBODYSKIN Hormonal Acne Supplement a full 60 to 90 days before evaluating results. Internal systems like hormone metabolism and liver detoxification work on a slower timeline than topical products, and most people notice the clearest shift in breakout frequency and severity after consistent use through at least one full cycle.

Take: 2 to 3 capsules daily with a meal. Never take on an empty stomach.

Starting Dose: If you weigh less than 125 lb, begin with 2 capsules per day.

Frequency: Take daily as part of a consistent routine. Internal hormone and detox shifts take time to reflect in the skin, so consistency over 60 to 90 days is key to seeing results.