Most exfoliating serums rely on acids like glycolic or lactic acid to dissolve the bonds between dead skin cells. GlyMed Plus Bio Renewal Serum uses Hexanoyl Dipeptide-3 Norleucine Acetate, a peptide that signals the skin to initiate its own natural shedding process instead of chemically dissolving surface cells. This makes it a gentler, more biomimetic approach to cellular renewal, with less risk of irritation, sensitivity, or disruption to the skin barrier.

The formula contains four distinct peptides, each targeting a different function. Hexanoyl Dipeptide-3 Norleucine Acetate drives cellular renewal by mimicking the skin's natural exfoliation signal. Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 support collagen synthesis and help restore firmness and skin density. Acetyl Hexapeptide-8 relaxes the repetitive muscle contractions responsible for expression lines. Together, they create a multi-layered approach to skin renewal that a single-peptide formula cannot match.

Yes, it is a good fit for sensitive skin that still wants renewal results. Because the exfoliation mechanism is driven by peptides rather than acids, there is no risk of the pH-related irritation that acid-based exfoliants can cause. Copper Tripeptide-1 in the formula also has known skin-calming and regenerative properties that support the skin's barrier during the renewal process.

The formula uses tetrahexyldecyl ascorbate, which is an oil-soluble, highly stable ester form of vitamin C. Unlike L-ascorbic acid, it does not oxidize quickly on contact with air or light, making it significantly more shelf-stable. It penetrates effectively into the skin and converts to active vitamin C once absorbed, where it works to neutralize free radicals and support a more even, clearer tone.

The recommended use is in the evening, and that is when the peptides can work most effectively alongside the skin's natural overnight renewal cycle. However, because the formula does not contain exfoliating acids or retinoids, it is not inherently photosensitizing. If you choose to use it in the morning, apply a broad-spectrum SPF afterward to protect the skin and support the brightening results the vitamin C and antioxidants in the formula are working toward.

The formula includes green tea leaf extract, grape seed extract, olive leaf extract, and tocopherol, a form of vitamin E, alongside tetrahexyldecyl ascorbate. Together, they provide multi-pathway antioxidant protection against environmental damage, which is one of the primary drivers of uneven tone, dullness, and accelerated skin aging. Moringa oleifera seed oil adds additional protective and nourishing properties to the formula.

Because this serum works by supporting the skin's natural cellular turnover rather than forcing surface exfoliation, results build gradually. Most users begin to notice improved texture and a clearer, more even tone within four to six weeks of consistent nightly use. Firmness and visible reduction in fine lines typically become more apparent after eight to twelve weeks, as collagen-supporting peptides require sustained use to show structural changes.

Art of Skin Care is an authorized retailer of GlyMed Plus, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if GlyMed Plus Bio Renewal Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.