What Is the Nano Infusion Pen?
The Art of Skin Care Nano Infusion Pen is a state-of-the-art, non-invasive device designed to gently infuse the skin with nourishing serums. Unlike traditional microneedling, the Nano Pen does not puncture the skin; instead, it uses microscopic tips to create temporary pathways on the skin’s surface. This enhances absorption of active ingredients, stimulates natural collagen production, and supports skin healing—without pain or downtime.
Why Do This Treatment?
Nano infusion is ideal for those looking to:
Deeply hydrate the skin and restore a healthy glow
Improve the delivery of peptides, antioxidants, and hyaluronic acid
Encourage collagen renewal for firmer, smoother skin
Soothe and strengthen barrier function while enhancing healing
Because it is so gentle, this treatment can be done up to 3 times per week to maintain hydration and keep skin looking plump and radiant.
Who Is It For?
This treatment is safe and effective for most skin types, including sensitive skin. It’s perfect for anyone who wants to boost their results between professional treatments, refresh dull skin, or amplify the benefits of their serums.
Step One: Epicutis Essential Cleanse
Start with the oil – Apply the Epicutis Cleansing Oil to dry skin and massage thoroughly to dissolve makeup, sunscreen, and impurities.
Add the Enzyme Powder – Sprinkle about 1 tablespoon of the Epicutis Enzyme Powder into the palm of your hand.
Activate the powder – Wet your other hand, then rub your palms together briskly to create a light, slippery cream.
Massage it in – Apply the cream to your face and massage gently. Rewet your hands as needed to keep the cream active, and continue massaging for a full 2 minutes to allow the enzymes to work their magic.
Rinse well – Finish by rinsing thoroughly with lukewarm water.
Step Two: Serum Selection
The magic of the Glow Infusion Treatment lies in delivering powerhouse serums deep into the skin. Because the Nano Infusion Pen creates temporary micro-channels, your skin can absorb nutrients up to several times more effectively than with topical application alone.
For best results, always choose a water-based serum rich in:
Hyaluronic Acid – for deep hydration and plump, dewy skin
Peptides – to stimulate collagen and elastin production, improving firmness
Antioxidants – to protect against free radical damage and support healing
Avoid: Oils, exfoliating acids, and retinol-based serums. These can cause irritation when infused and are better applied in your regular routine outside of treatment days.
Our Top Pick: Epicutis Lipid Serum – This clinical-grade serum is formulated with patented TSC (tetrahexyldecyl ascorbate) and powerful antioxidants to soothe inflammation, restore balance, and strengthen the skin barrier. It’s lightweight, water-based, and designed to deliver maximum hydration and anti-aging benefits, making it the perfect infusion partner.
Pro Tip: If you also use advanced regenerative serums like Plated Intense Serum or NeoGenesis Recovery, apply them after your nano infusion to protect the integrity of their delicate delivery systems.
- Attach Cartridge: Secure the single-use nano-cartridge.
- Power On: Press and hold the power button to activate; press again to increase intensity (RPM).
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Select Intensity:
- Level 1 (Blue): Use level 1 for infusion.
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Procedure:
- Moisten each section with your chosen serum.
- Perform nano passes section by section, keeping the skin damp (reapply as needed).
- Avoid the inner eyelid areas and do not apply pressure—simply glide over the skin.
Step Three: Nano Infusion Treatment
Now that your skin is prepped and layered with a nourishing serum, it’s time to let the Nano Infusion Pen do its work. The device uses ultra-fine tips to gently press the serum deeper into the skin, creating micro-channels that dramatically enhance absorption while stimulating natural collagen production.
Attach Cartridge – Secure the single-use nano-cartridge to your device.
Power On – Press and hold the power button to activate; press again to adjust the speed (RPM).
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Select Intensity –
Level 1 (Blue): Ideal for infusion treatments and suitable for all skin types.
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Procedure –
Apply a generous layer of Epicutis Lipid Serum to one section of the face.
Glide the Nano Pen slowly and evenly over that area, allowing the device to infuse the serum into the skin.
Reapply serum as needed to keep the skin damp and comfortable.
Move systematically section by section until the entire face has been treated.
Avoid the delicate inner eyelid area.
Think of this step as “power-charging” your skincare—the Nano Pen transforms your serum from surface hydration into deep, corrective nourishment.
Step Four: Skin Recovery Boost
After infusion, your skin is highly receptive to calming and restorative treatments. To maximize your results and accelerate collagen support, finish with a soothing mask.
Apply: Smooth on a generous layer of the CO₂ Lift Pro Carboxy Treatment Mask.
Set: Allow it to work for 45–60 minutes, infusing the skin with oxygen to enhance healing, hydration, and firmness.
Remove: Gently peel away the mask and clear any residue with a damp cloth.
Pro Tip: When paired with the Nano Infusion Pen, the CO₂ Lift Pro significantly enhances collagen production and skin recovery, leaving your complexion plump, calm, and luminous.
Nano Infusion Pen: Treatment Comparison
| Feature | Glow Infusion Treatment | Resurfacing Treatment |
|---|---|---|
| Purpose | Deep hydration, serum infusion, collagen support, and barrier repair | Gentle resurfacing, retexturizing, and smoothing skin tone & texture |
| Frequency | Up to 3 times per week | Once every 4–5 weeks |
| Serum Type | Water-based serums with hyaluronic acid, peptides, and antioxidants (ex: Epicutis Lipid Serum) | Healing serums post-treatment (ex: Plated Intense Serum or NeoGenesis Recovery Serum) |
| Device Intensity | Level 1 (Blue) for infusion | Level 2 (Green) for sensitive areas, Level 3 (Red) for stronger resurfacing |
| Best For | Boosting hydration, soothing sensitivity, supporting collagen, and enhancing daily skincare results | Improving texture, refining pores, softening fine lines, and refreshing overall radiance |
| Recovery | No downtime—skin may feel dewy or slightly flushed for a few minutes | Possible mild redness and light exfoliation in the days following |
| Optional Boost | CO₂ Lift Pro Mask for collagen support & hydration | CO₂ Lift Pro Mask for enhanced healing & recovery |
Think of the Glow Infusion as your “maintenance” treatment to keep skin nourished and radiant, while the Resurfacing Treatment is your monthly reset for texture and renewal.
Author
Jeana LeClerc is a licensed esthetician, Certified Acne Specialist, and the founder and CEO of Art of Skincare . With over 20 years of hands-on experience in the skincare industry, Jeana specializes in regenerative skincare —a powerful, holistic alternative to conventional anti-aging treatments.
Rejecting the pressure of injectables and invasive procedures, Jeana champions science-backed, skin-nourishing solutions that support healthy, youthful skin from the inside out. Her mission is to help clients achieve lasting skin transformation through personalized routines, professional-grade products, and a deep understanding of how the skin functions and regenerates.
At Art of Skincare, Jeana leads a team of expert estheticians dedicated to delivering results-driven skincare, from clearing acne to supporting healthy aging . Her blog and online consultations are trusted resources for those seeking radiant, resilient skin without compromise.