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iS Clinical Brightening Serum

This nighttime brightening serum delivers powerful results without irritation. Designed to work in synergy with iS Clinical Brightening Complex (your AM brightener), the two pair seamlessly for around-the-clock support in targeting discoloration, rough texture, and visible signs of aging.

This advanced formula gently resurfaces with natural sources of glycolic and salicylic acids, helping to smooth skin texture, soften fine lines and wrinkles, and visibly fade age spots and hyperpigmentation—both on the face and body.

Whether you're treating a blotchy, uneven complexion or stubborn discoloration, this PM serum provides a gentle but effective path to luminosity, refining pores and restoring balance while you sleep.

  • Gently exfoliates without irritation
  • Reduces dark spots and hyperpigmentation
  • Refines rough texture, pores, and fine lines
  • Evens out blotchy, uneven tone
  • Safe for sensitive, reactive, and compromised skin
  • Ideal evening partner to iS Clinical Brightening Complex
  • pH 3.4 ± 0.5

1 oz or 0.5 oz | Dropper Bottle

Acne Safe

iS Clinical Brightening Serum

iS Clinical Brightening Serum is your evening essential for radiant, even-toned skin and a refined, smooth texture.

5.0
Rated 5.0 out of 5 stars
36 Reviews
Regular price $87.00
Unit price
per 
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Pigmentation
Lotion bottle icons

Best For:

  • Combination
  • Dry
  • Normal
  • Oily
  • Sensitive

iS Clinical Brightening Serum

This nighttime brightening serum delivers powerful results without irritation. Designed to work in synergy with iS Clinical Brightening Complex (your AM brightener), the two pair seamlessly for around-the-clock support in targeting discoloration, rough texture, and visible signs of aging.

This advanced formula gently resurfaces with natural sources of glycolic and salicylic acids, helping to smooth skin texture, soften fine lines and wrinkles, and visibly fade age spots and hyperpigmentation—both on the face and body.

Whether you're treating a blotchy, uneven complexion or stubborn discoloration, this PM serum provides a gentle but effective path to luminosity, refining pores and restoring balance while you sleep.

  • Gently exfoliates without irritation
  • Reduces dark spots and hyperpigmentation
  • Refines rough texture, pores, and fine lines
  • Evens out blotchy, uneven tone
  • Safe for sensitive, reactive, and compromised skin
  • Ideal evening partner to iS Clinical Brightening Complex
  • pH 3.4 ± 0.5

1 oz or 0.5 oz | Dropper Bottle

iS Clinical Brightening Serum

5.0
Rated 5.0 out of 5 stars
Based on 36 reviews
Total 5 star reviews: 35 Total 4 star reviews: 1 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
36 reviews
  • MV
    Melissa V.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Serum
    I recommend this product
    How old are you? 50-65
    Rated 5 out of 5 stars
    11 months ago
    iS Clinical Brightening Serum

    Been using this brightening serum

    Been using this brightening serum consistently for a few weeks. Hoping to lighten a few dark spots that have recently popped up. Haven't had significant results yet but I remain hopeful. Love the high quality ingredients in iS Clinical products.

  • TB
    Theresa B.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Serum
    I recommend this product
    How old are you? 50-65
    Rated 5 out of 5 stars
    11 months ago
    iS Clinical Cleansing Complex

    My favorite cleanser

    I love this cleanser, it's very gentle for my dry sensitive skin but keeps my pores clear and gently exfoliates my skin.

  • KV
    KELLI V.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Serum
    I recommend this product
    How old are you? 50-65
    Rated 5 out of 5 stars
    12 months ago
    iS Clinical Brightening Serum

    So far so good

    So far so good

  • LM
    Lorena M.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Serum
    I recommend this product
    How old are you? 30-39
    Rated 5 out of 5 stars
    1 year ago
    iS Clinical Cleansing Complex

    keeper

    love this gel cleanser, doesn't overdry, great on sensitive acne prone skin, lifts up all the makeup residue, dirt and oil, leaves skin clean and hydrated, (I use this daily after removing my makeup with Corley's cleansing oil )

  • CS
    cheryl s.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Serum
    I recommend this product
    How old are you? 30-39
    Rated 5 out of 5 stars
    1 year ago
    iS Clinical Brightening Serum

    Improving melasma

    I started this based on the suggestion of MJ during my annual

    consultation. I have been using it every other night for under 2 weeks and I am amazed to say I can already see lightening in my melasma! It tingles a bit after putting it on but not bothersome. I don't appreciate any fragrance/smell. I am definitely going to continue this product!

Why Art of Skin Care?

At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.