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iS Clinical Brightening Complex

iS Clinical Brightening Complex takes a holistic, science-backed approach to enhancing skin brightness and overall health. This powerful daytime formula utilizes pharmaceutical-grade botanicals, stabilized vitamin C, and advanced DNA-repairing enzymes (Extremozymes) to visibly diminish dark spots, even out skin tone, and promote long-term skin resilience.

Designed to work synergistically with iS Clinical Brightening Serum, this duo creates a complete AM/PM regimen for tackling hyperpigmentation, rough texture, and dullness. Use the Brightening Complex in the morning to protect, hydrate, and prepare the skin, then follow with the Brightening Serum at night for gentle exfoliation and deeper pigment correction.

Tip: Many normal to oily skin types enjoy Brightening Complex as their daytime moisturizer, thanks to its lightweight, fast-absorbing texture and multi-action benefits.

  • Brightens and evens skin tone
  • Diminishes dark spots and hyperpigmentation
  • Provides gentle exfoliation for a smoother texture
  • Deeply hydrates and supports barrier health
  • Defends against environmental damage with Extremozymes®
  • Ideal AM partner to iS Clinical Brightening Serum
  • pH 3.3 ± 0.5

1 oz | Airless Pump

Acne Safe

iS Clinical Brightening Complex

A multitasking morning treatment that brightens, hydrates, and protects, while setting the stage for your evening brightening routine.

4.9
Rated 4.9 out of 5 stars
9 Reviews
Regular price $159.00
Unit price
per 
iS Clinical Brightening Complex - Art of Skin Care
iS Clinical Brightening Complex
1 oz
Regular price $159.00
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Dullness
  • Pigmentation
  • Sun Damage
  • Fine Lines
Lotion bottle icons

Best For:

  • Combination
  • Dry
  • Normal
  • Oily

iS Clinical Brightening Complex

iS Clinical Brightening Complex takes a holistic, science-backed approach to enhancing skin brightness and overall health. This powerful daytime formula utilizes pharmaceutical-grade botanicals, stabilized vitamin C, and advanced DNA-repairing enzymes (Extremozymes) to visibly diminish dark spots, even out skin tone, and promote long-term skin resilience.

Designed to work synergistically with iS Clinical Brightening Serum, this duo creates a complete AM/PM regimen for tackling hyperpigmentation, rough texture, and dullness. Use the Brightening Complex in the morning to protect, hydrate, and prepare the skin, then follow with the Brightening Serum at night for gentle exfoliation and deeper pigment correction.

Tip: Many normal to oily skin types enjoy Brightening Complex as their daytime moisturizer, thanks to its lightweight, fast-absorbing texture and multi-action benefits.

  • Brightens and evens skin tone
  • Diminishes dark spots and hyperpigmentation
  • Provides gentle exfoliation for a smoother texture
  • Deeply hydrates and supports barrier health
  • Defends against environmental damage with Extremozymes®
  • Ideal AM partner to iS Clinical Brightening Serum
  • pH 3.3 ± 0.5

1 oz | Airless Pump

iS Clinical Brightening Complex

4.9
Rated 4.9 out of 5 stars
Based on 9 reviews
Total 5 star reviews: 8 Total 4 star reviews: 1 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
9 reviews
  • AS
    Allison S.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 40-49
    Rated 5 out of 5 stars
    8 months ago
    iS Clinical Brightening Complex

    Slight burning after applying. Have

    Slight burning after applying. Have not had any other issues.

  • CS
    cheryl s.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 30-39
    Rated 5 out of 5 stars
    9 months ago
    iS Clinical Brightening Complex

    I am in love with

    I am in love with this product for lightening my pigmentation. I have only been using this product for 2 weeks along with the iS brightening serum and I have already seen massive improvements in my melasma! It has a mild/pleasant smell and absorbs quickly into my skin. It is not greasy and does not pill with other products I am using in sunscreen.

  • MV
    Melissa V.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 50-65
    Rated 5 out of 5 stars
    11 months ago
    iS Clinical Brightening Complex

    Keeper!

    I have been experimenting with iS Clinical Products after having great success with their Active Peel. I have been using the Brightening Complex for about 4 weeks and am thrilled with the results. My skin looks brighter, healthier and wonderfully hydrated. Look forward to adding more iS Clinical products to my routine.

  • LC
    Lindsay C.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 30-39
    Rated 5 out of 5 stars
    1 year ago
    iS Clinical Brightening Complex

    So far I'm inpressed

    I'm have only been in sing this for a couple weeks, but so far impressed. Definitely wake up with more glow. I have Melasma, so I'm not sure if it will help with that yet but I'm hopeful!

  • GR
    Gretchen R.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 50-65
    Rated 5 out of 5 stars
    1 year ago
    iS Clinical Brightening Complex

    Can't do without

    This product is amazing and I have sensitive skin and it does not bother me. It definitely helps keep brown spots at bay in between my BBL's. Love all the Is clinical Products.

Why Art of Skin Care?

At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.