iS Clinical Hydra-Cool Serum
This cooling serum with menthol provides relief to dry, dehydrated, or irritated skin while boosting hydration with hyaluronic acid and providing antioxidant protection. Centella asiatica combines with vitamin B to promote healing and boost overall skin barrier health. The addition of mushroom extract offers further hydrating and skin strengthening benefits while reducing inflammation.
- Ultra-hydrating
- Cools and soothes
- Reduces redness
- Anti-inflammatory
- Provides antioxidant protection
- 6.25 pH +/- 0.5
1 oz or 0.5 oz | Pump
All skin types looking for hydration, soothing, and to even skin tone will love this serum. Especially beneficial for dry or sensitive skin types. Rosacea or redness prone skin will enjoy the anti-inflammatory benefits.
Excellent option for soothing sunburns!
After cleansing and toning, apply a pea-sized amount to face, neck, and chest in morning and evening, layer with your favorite moisturizer. Be sure to follow with SPF when used in the AM.
- Sodium Hyaluronate: The purest, salt form of hyaluronic acid, a master humectant that holds up to 1,000 times its weight in water to provide maximum hydration and plumping benefits to thirsty skin.
- Vitamin B5 (Pantothenic Acid): Demonstrates significant potential to reduce hormonal acne and control oil production. Also shown to help the oxidation process, supporting healthy digestion that can also reduce inflammation and increase nutrient absorption.
- Centella Asiatica Extract: Helps to strengthen and repair the skin's moisture barrier with potent anti-inflammatory benefits and antioxidant protection.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Sodium Hyaluronate, Pantothenic Acid, Pentylene Glycol, Menthol, Phenoxyethanol, Asiaticoside, Polyporus Umbellatus (Mushroom) Extract, Asiatic Acid, Madecassic Acid, Blue 1 (CI 42090).
iS Clinical Hydra-Cool Serum hydrates, soothes, and calms dry, irritated, or redness-prone skin.
- Unit price
- /per

Primary Concerns:
- Compromised Barrier
- Dehydration
- Oil Balancing
- Inflammation

Best For:
- Combination
- Dry
- Normal
- Oily
- Sensitive
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iS Clinical Hydra-Cool Serum
This cooling serum with menthol provides relief to dry, dehydrated, or irritated skin while boosting hydration with hyaluronic acid and providing antioxidant protection. Centella asiatica combines with vitamin B to promote healing and boost overall skin barrier health. The addition of mushroom extract offers further hydrating and skin strengthening benefits while reducing inflammation.
- Ultra-hydrating
- Cools and soothes
- Reduces redness
- Anti-inflammatory
- Provides antioxidant protection
- 6.25 pH +/- 0.5
1 oz or 0.5 oz | Pump
All skin types looking for hydration, soothing, and to even skin tone will love this serum. Especially beneficial for dry or sensitive skin types. Rosacea or redness prone skin will enjoy the anti-inflammatory benefits.
Excellent option for soothing sunburns!
After cleansing and toning, apply a pea-sized amount to face, neck, and chest in morning and evening, layer with your favorite moisturizer. Be sure to follow with SPF when used in the AM.
- Sodium Hyaluronate: The purest, salt form of hyaluronic acid, a master humectant that holds up to 1,000 times its weight in water to provide maximum hydration and plumping benefits to thirsty skin.
- Vitamin B5 (Pantothenic Acid): Demonstrates significant potential to reduce hormonal acne and control oil production. Also shown to help the oxidation process, supporting healthy digestion that can also reduce inflammation and increase nutrient absorption.
- Centella Asiatica Extract: Helps to strengthen and repair the skin's moisture barrier with potent anti-inflammatory benefits and antioxidant protection.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Sodium Hyaluronate, Pantothenic Acid, Pentylene Glycol, Menthol, Phenoxyethanol, Asiaticoside, Polyporus Umbellatus (Mushroom) Extract, Asiatic Acid, Madecassic Acid, Blue 1 (CI 42090).








Explore More Recommendations
iS Clinical Hydra-Cool Serum
- GTGinger T.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 30-39What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Blemish-prone, OilinessRated 4 out of 5 stars1 hour agoGreat, lightweight hydrating serum
I love the cooling effect of this serum and how it helps with redness/irritation. I pair it with a hydrating spray and find that to be the perfect combination for me
Was this helpful? - JJJessica J.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 18-29What are your skin concerns? Blemish-proneRated 5 out of 5 stars1 year agoiS Clinical Hydra-Cool Serum
LOVE
I LOVE this product! One of my absolute favorite staple products for hydration!
Was this helpful? - SPShaila P.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 18-29What are your skin concerns? Blemish-proneRated 5 out of 5 stars1 year agoiS Clinical Hydra-Cool Serum
Best Product for my Acne Prone Skin
I absolutely love the cooling minty feeling this product gives my skin. It provides excellent hydration in addition to my daily moisturizer. When I don't use it, my skin dries out quickly but this product helps maintain that extra layer of moisture that my skin needs to thrive.
Was this helpful? - KBKasey B.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 40-49Rated 5 out of 5 stars2 years agoiS Clinical Hydra-Cool Serum
My teenager loves this product!
My teenager loves this product! She says she likes it bc it has a fast drying time.
Was this helpful? - JVJacky V.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 18-29What are your skin concerns? Blemish-proneRated 5 out of 5 stars2 years agoiS Clinical Hydra-Cool Serum .5oz
Feels nice on skin
I have struggled with my skin for years. I have skin prone to clogging and is very sensitive to products. Hence this serum feels sooo good on my skin, no sticky residue or irritation. I'm healing my skin and this is helping so much.
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Why Art of Skin Care?
At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.