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Smooth, Plump & Rejuvenate: Targeted Regenerative Skincare for Lips & Neck

When it comes to anti-aging skincare , many people focus all their attention on the face—but the lips, mouth area, and neck often show signs of aging first. Fine lines around the lips (sometimes called smoker’s lines ), lip thinning , and crepey neck skin are common concerns that are difficult to treat with traditional skincare products.That’s why we created the AOS Nano Pen Regenerative Treatment for Lips & Neck —a professional-level at-home treatment that uses advanced nano-needling technology , exosome therapy , and an oxygen-infused carboxy mask to smooth, firm, and plump these delicate areas.

Why Focus on Lips & Neck?

Common Concerns:
  • Lip Lines: Vertical lines above the lips, often from sun damage, repetitive movement, or collagen loss.
  • Lip Thinning: Lips naturally lose volume as collagen and hyaluronic acid levels decline with age.
  • Crepey Neck Skin: The thin skin on the neck loses elasticity quickly, leading to sagging and texture changes.
  • Tech Neck Wrinkles: Horizontal lines across the neck caused by constantly looking down at phones and screens.

Because the skin in these areas is thinner and more delicate , it requires specialized care to stimulate collagen while avoiding irritation.

What is the AOS Nano Pen Regenerative Treatment for Lips & Neck?

This at-home treatment combines 3 powerful technologies to rejuvenate and restore the lips, mouth area, and neck:

  1. Nano-needling: Creates thousands of micro-channels to trigger natural collagen production and enhance product absorption.

  2. Exosome Therapy: Delivers powerful growth factors, peptides, and antioxidants to support healing and boost skin regeneration.

  3. CO2Lift Pro Carboxy Mask: Floods the skin with oxygen to calm inflammation , improve elasticity, and plump fine lines.

Step-by-Step Treatment Guide

Step 1: Cleanse & Prep

Always start with clean skin to ensure optimal absorption of products. Cleanse the lips, mouth area, and neck using a gentle, hydrating cleanser such as Dr. esthé Moisture Cleansing Gel.

Optional: Use LED light therapy or microcurrent beforehand to boost ATP production and energize skin cells.

Step 2: Nano-Needling for Lips & Neck


Using the AOS Nano Pen , gently glide over:

  • Lip border (vermillion border)
  • Upper lip area (vertical lines)
  • Smile lines (nasolabial folds)
  • Entire neck (focusing on horizontal lines and crepey skin)

Pro Tip: Keep skin hydrated during nano-needling with Le Mieux Iso Cell Recovery Solution to ensure a smooth glide and prevent irritation.

Recommended Intestity:

  • Level 2 (Green): For delicate areas like the lips.
  • Level 3 (Red): For the neck and lower face.

Step 3: Exosome Infusion

Immediately after nano-needling, apply a Plated Skin Science Intense Serum to kickstart repair.

Step 4: CO2Lift Pro Carboxy Mask

The final step is applying the CO2Lift Pro Carboxy Gel Mask to the lips, mouth area, and neck. This oxygenating mask creates a hyperbaric-like effect , flooding the skin with CO2 to trigger a rush of oxygen-rich blood flow .

Post-Treatment Care


After your treatment, apply:

How Often Should You Treat Lips & Neck?

  • Once every 4 weeks

Why This Treatment Works (Better Than Lip Balms or Neck Creams)

Traditional lip balms and neck creams can only do so much. The AOS Nano Pen Regenerative Treatment works below the surface , using nano-technology to stimulate natural collagen and elastin production while delivering potent ingredients deeper into the skin .The combination of nano-needling, exosome therapy, and carboxy oxygen infusion creates a multi-layered regenerative response —something regular products just can’t match.

Who Should Try This Treatment?

This treatment is perfect for anyone noticing:

  • Fine lines around the mouth 
  • Thinning lips 
  • Crepey neck skin 
  • Tech neck wrinkles 
  • Dull, dehydrated skin on lips or neck