iS Clinical Active Serum
This powerful, botanical serum checks all the boxes. It provides potent healthy aging benefits, reduces blemishes, and evens skin tone and texture. Natural forms of glycolic and salicylic acid provide gentle exfoliation, boosting cell turnover and clarifying the skin to promote clear pores and minimize fine lines and wrinkles. Bilberry and mushroom extracts further encourage collagen production and hydration in the skin to enhance barrier function to plump and firm the skin and improve overall skin health.
- Gently exfoliates
- Diminished appearance of fine lines and wrinkles
- Evens skin tone and texture
- Reduces blemishes
- Refines pores
- 5.6 pH +/- 0.5
1 oz or 0.5 oz | Dropper Bottle
All skin types looking to minimize the visible signs of aging or blemishes while promoting a more even skin tone and texture will love this serum!
The menthol in this serum creates an active tingling sensation. Try mixing in your hand with Hydra-Cool Serum to improve hydration and absorption with a soothing effect.
After cleansing and toning, apply 3-5 drops to face, neck, and chest in morning or evening, layer with your favorite moisturizer. Be sure to follow with SPF when used in the AM.
- Sugar Cane Extract: Natural source of glycolic acid, provides more gentle exfoliation while also acting as a humectant to hydrate the skin.
- Bilberry (Vaccinium Myrtillus) Extract: Antioxidant-rich ingredient that gently exfoliates, promotes healthy blood flow, and increases collagen production with calming effects for overall skin health.
- Willow Bark Extract: A natural form of salicylic acid that exfoliates and refines pores while calming inflammation.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol.
iS Clinical Active Serum is a lightweight, powerful formula that targets blemishes, fine lines, and dullness while brightening skin.
- Unit price
- /per

Primary Concerns:
- Acne
- Large Pores
- Fine Lines
- Wrinkles

Best For:
- Combination
- Dry
- Normal
- Oily
- Sensitive
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iS Clinical Active Serum
This powerful, botanical serum checks all the boxes. It provides potent healthy aging benefits, reduces blemishes, and evens skin tone and texture. Natural forms of glycolic and salicylic acid provide gentle exfoliation, boosting cell turnover and clarifying the skin to promote clear pores and minimize fine lines and wrinkles. Bilberry and mushroom extracts further encourage collagen production and hydration in the skin to enhance barrier function to plump and firm the skin and improve overall skin health.
- Gently exfoliates
- Diminished appearance of fine lines and wrinkles
- Evens skin tone and texture
- Reduces blemishes
- Refines pores
- 5.6 pH +/- 0.5
1 oz or 0.5 oz | Dropper Bottle
All skin types looking to minimize the visible signs of aging or blemishes while promoting a more even skin tone and texture will love this serum!
The menthol in this serum creates an active tingling sensation. Try mixing in your hand with Hydra-Cool Serum to improve hydration and absorption with a soothing effect.
After cleansing and toning, apply 3-5 drops to face, neck, and chest in morning or evening, layer with your favorite moisturizer. Be sure to follow with SPF when used in the AM.
- Sugar Cane Extract: Natural source of glycolic acid, provides more gentle exfoliation while also acting as a humectant to hydrate the skin.
- Bilberry (Vaccinium Myrtillus) Extract: Antioxidant-rich ingredient that gently exfoliates, promotes healthy blood flow, and increases collagen production with calming effects for overall skin health.
- Willow Bark Extract: A natural form of salicylic acid that exfoliates and refines pores while calming inflammation.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol.







Explore More Recommendations
iS Clinical Active Serum
- AWAdrienne W.Verified BuyerReviewingiS Clinical Active SerumI recommend this productHow old are you? 40-49What are your skin concerns? Blemish-proneRated 4 out of 5 stars9 months agoiS Clinical Active Serum
Great serum
One of my favorite serums. This is my first time purchasing. I've used samples in the past and used every last drop! Haha! If it was more affordable I'd rate it 5 stars. Love it! It helps keep my skin clear and healthy looking, and a little goes a long way.
Was this helpful? - JCJ C.Verified BuyerReviewingiS Clinical Active SerumI recommend this productHow old are you? 50-65What are your skin concerns? Blemish-proneRated 5 out of 5 stars9 months agoiS Clinical Active Serum
I have been using this
I have been using this serum for a couple years now for my acne. Rather than picking at my acne, which I did which is why I had acne scars, I put a drop on my breakouts. This serum calms my skin, reduces inflammation and dries up my acne.so I know longer have to irritate it.
Was this helpful? - JRJoseph R.Verified BuyerReviewingiS Clinical Active SerumI recommend this productHow old are you? 30-39Rated 5 out of 5 stars11 months agoiS Clinical Active Serum
Amazing
Amazing stuff , this is a staple in my routine now. I am actually considering switching all of my producta to is clinical, I look awesome!
Was this helpful? - APAnita P.Verified BuyerReviewingiS Clinical Active SerumI recommend this productHow old are you? 30-39Rated 5 out of 5 stars1 year agoiS Clinical Active Serum
Tingly
This is my 5th bottle and I literally will never stop buying it. It's great for breakouts
Was this helpful? - SPShaila P.Verified BuyerReviewingiS Clinical Active SerumI recommend this productHow old are you? 18-29What are your skin concerns? Blemish-proneRated 5 out of 5 stars1 year agoiS Clinical Active Serum
The active serum is one
The active serum is one of my favorites, I can tell a difference in the dark spots and the lines in my skin after incorporating this into my skincare routine. It has a menthol-like burning sensation when it first goes on but that quickly goes away. It comes in very nice packaging and comes sealed up with the dropper inside the box separately.
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Why Art of Skin Care?
At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.
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