Epicutis Lipid Serum
Soothe, Strengthen, and Restore in a Single Step
Formulated with just eight gentle yet powerful ingredients, the Epicutis Lipid Serum is the cornerstone of any healing skincare routine. Powered by a therapeutic concentration of TSC, a patented anti-inflammatory lipid, this silky serum delivers immediate relief for dry, stressed, and post-procedure skin while working over time to calm redness, rebuild the skin barrier, and defend against collagen loss at the cellular level.
Lightweight and fast-absorbing, it melts into the skin with a smooth, non-greasy finish, making it the perfect first step post-cleanse for anyone seeking to restore balance and resilience.
- Instantly calms inflammation and visibly reduces redness
- Deeply hydrates and supports the skin’s lipid barrier
- Helps strengthen skin against environmental stress and collagen breakdown
- Safe and soothing for sensitive, dry, or post-treatment skin
- Lasts 3 months when using a pea sized amount twice per day!
This serum is our estheticians’ go-to skin savior! Keep it in the fridge and press it on post-peel, post-sun, or post-flare-up for an instant cooling calm-down that feels like a reset button for your skin.
Apply to clean, dry skin morning and night. Dispense 1–2 drops into the palms and gently press into the face, neck, and décolleté. Follow with Hyvia® Crème or your preferred moisturizer.
- TSC (Disodium Tetramethylhexadecenyl Succinoyl Cysteine): A breakthrough super-lipid that strengthens the skin’s natural barrier while providing powerful protection against environmental stressors like UV rays and pollution.
- Sodium Hyaluronate: The purest, salt form of hyaluronic acid, a master humectant that holds up to 1,000 times its weight in water to provide maximum hydration and plumping benefits to thirsty skin.
- Propanediol: Moisturizes skin, improves texture, and assists with product absorption. Also contains antimicrobial properties.
- Glycerin: Provides long-lasting, intense moisture retention.
Water, Propanediol, Pentylene Glycol, Glycerin, Sodium Hyaluronate, Disodium Tetramethylhexadecenyl Succinoyl Cysteine, Sodium Phytate, Citric Acid
Epicutis Lipid Serum strengthens the skin barrier, calms inflammation, and reduces fine lines—a powerful, lipid-rich serum for healthy, youthful skin.
- Unit price
- /per
Primary Concerns:
- Compromised Barrier
- Inflammation
- Redness/Rosacea
- Dehydration
Best For:
- Dry
- Normal
- Oily
- Combination
- Sensitive
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Epicutis Lipid Serum
Soothe, Strengthen, and Restore in a Single Step
Formulated with just eight gentle yet powerful ingredients, the Epicutis Lipid Serum is the cornerstone of any healing skincare routine. Powered by a therapeutic concentration of TSC, a patented anti-inflammatory lipid, this silky serum delivers immediate relief for dry, stressed, and post-procedure skin while working over time to calm redness, rebuild the skin barrier, and defend against collagen loss at the cellular level.
Lightweight and fast-absorbing, it melts into the skin with a smooth, non-greasy finish, making it the perfect first step post-cleanse for anyone seeking to restore balance and resilience.
- Instantly calms inflammation and visibly reduces redness
- Deeply hydrates and supports the skin’s lipid barrier
- Helps strengthen skin against environmental stress and collagen breakdown
- Safe and soothing for sensitive, dry, or post-treatment skin
- Lasts 3 months when using a pea sized amount twice per day!
This serum is our estheticians’ go-to skin savior! Keep it in the fridge and press it on post-peel, post-sun, or post-flare-up for an instant cooling calm-down that feels like a reset button for your skin.
Apply to clean, dry skin morning and night. Dispense 1–2 drops into the palms and gently press into the face, neck, and décolleté. Follow with Hyvia® Crème or your preferred moisturizer.
- TSC (Disodium Tetramethylhexadecenyl Succinoyl Cysteine): A breakthrough super-lipid that strengthens the skin’s natural barrier while providing powerful protection against environmental stressors like UV rays and pollution.
- Sodium Hyaluronate: The purest, salt form of hyaluronic acid, a master humectant that holds up to 1,000 times its weight in water to provide maximum hydration and plumping benefits to thirsty skin.
- Propanediol: Moisturizes skin, improves texture, and assists with product absorption. Also contains antimicrobial properties.
- Glycerin: Provides long-lasting, intense moisture retention.
Water, Propanediol, Pentylene Glycol, Glycerin, Sodium Hyaluronate, Disodium Tetramethylhexadecenyl Succinoyl Cysteine, Sodium Phytate, Citric Acid
Explore More Recommendations
Epicutis Lipid Serum
- HSHeidi S.Verified BuyerReviewingEpicutis Lipid SerumI recommend this productHow old are you? 18-29What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Acne, Blemish-prone, Dryness, OilinessRated 5 out of 5 stars15 hours agoLove
Love! So hydrating definitely need to be consistent with use to see a difference but it really does add so much moisture to my skin!
Was this helpful? - YBYulissa B.Verified BuyerReviewingEpicutis Lipid SerumI recommend this productHow old are you? 40-49What is your skin type? OilyWhat is your skin tone? FairWhat are your skin concerns? AgeingRated 5 out of 5 stars1 month agoAbsolutely love it
It is worth every penny!
Was this helpful? - KMKristen M.Verified BuyerReviewingEpicutis Lipid SerumI recommend this productHow old are you? 40-49What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Acne, Ageing, Blemish-prone, Sensitivity, DrynessRated 5 out of 5 stars1 month agoGame changer
Healed post Accutane atopic dermatitis on my face. Expensive but worth it, fantastic product. I use daily and it’s something that I make sure I never run out of.
Was this helpful? - MGMarci G.Verified BuyerReviewingEpicutis Lipid SerumI recommend this productHow old are you? 50-65What is your skin type? NormalWhat is your skin tone? FairWhat are your skin concerns? Ageing, WrinklesRated 5 out of 5 stars1 month agoPricey
The presentation of this product is amazing. However the price point is pretty high. My skin does love it and it feels amazing on my skin. Not sure I’d would repurchase only because of the price. However if my skin was damaged and needed repair and / or relief I would definitely repurchase and feel confident that this product would help
Was this helpful? - DDrakeVerified BuyerReviewingEpicutis Lipid SerumI recommend this productHow old are you? 18-29What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Acne, Blemish-prone, Sensitivity, DrynessRated 5 out of 5 stars4 months agoExpensive but worth it!
I was hesitant to pay $250 for a product, but it did not disappoint. Soothes inflammation better than any product I've ever used.
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Why Art of Skin Care?
At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.