Epicutis Lipid Serum

Soothe, Strengthen, and Restore in a Single Step

Formulated with just eight gentle yet powerful ingredients, the Epicutis Lipid Serum is the cornerstone of any healing skincare routine. Powered by a therapeutic concentration of TSC, a patented anti-inflammatory lipid, this silky serum delivers immediate relief for dry, stressed, and post-procedure skin while working over time to calm redness, rebuild the skin barrier, and defend against collagen loss at the cellular level.

Lightweight and fast-absorbing, it melts into the skin with a smooth, non-greasy finish, making it the perfect first step post-cleanse for anyone seeking to restore balance and resilience.

  • Instantly calms inflammation and visibly reduces redness
  • Deeply hydrates and supports the skin’s lipid barrier
  • Helps strengthen skin against environmental stress and collagen breakdown
  • Safe and soothing for sensitive, dry, or post-treatment skin
  • Lasts 3 months when using a pea sized amount twice per day!
Acne Safe
New

Epicutis Lipid Serum

Epicutis Lipid Serum strengthens the skin barrier, calms inflammation, and reduces fine lines—a powerful, lipid-rich serum for healthy, youthful skin.

5.0
Rated 5.0 out of 5 stars
8 Reviews
Regular price $250.00
Unit price
per 
Availability
 
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Compromised Barrier
  • Inflammation
  • Redness/Rosacea
  • Dehydration
Lotion bottle icons

Best For:

  • Dry
  • Normal
  • Oily
  • Combination
  • Sensitive

Epicutis Lipid Serum

Soothe, Strengthen, and Restore in a Single Step

Formulated with just eight gentle yet powerful ingredients, the Epicutis Lipid Serum is the cornerstone of any healing skincare routine. Powered by a therapeutic concentration of TSC, a patented anti-inflammatory lipid, this silky serum delivers immediate relief for dry, stressed, and post-procedure skin while working over time to calm redness, rebuild the skin barrier, and defend against collagen loss at the cellular level.

Lightweight and fast-absorbing, it melts into the skin with a smooth, non-greasy finish, making it the perfect first step post-cleanse for anyone seeking to restore balance and resilience.

  • Instantly calms inflammation and visibly reduces redness
  • Deeply hydrates and supports the skin’s lipid barrier
  • Helps strengthen skin against environmental stress and collagen breakdown
  • Safe and soothing for sensitive, dry, or post-treatment skin
  • Lasts 3 months when using a pea sized amount twice per day!

Essential Additions

Streamlined solutions for maximum results

Epicutis Oil Cleanser - Art of Skin Care

Epicutis Oil Cleanser

$85.00
Unit price
per 
Epicutis Hyvia Crème - Art of Skin Care

Epicutis Hyvia Crème

$195.00
Unit price
per 
Epicutis Hydrobiome Mist - Art of Skin Care

Epicutis Hydrobiome Mist

$75.00
Unit price
per 
Epicutis Lipid Recovery Mask for Eyes - Art of Skin Care

Epicutis Lipid Recovery Mask for Eyes

$105.00
Unit price
per 
5.0
Rated 5.0 out of 5 stars
Based on 8 reviews
Total 5 star reviews: 8 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
8 reviews
  • AL
    arlene l.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? Over 65
    What is your skin type? Dry
    What is your skin tone? Medium
    What are your skin concerns? Ageing, Dryness
    Rated 5 out of 5 stars
    3 minutes ago
    lipid serum

    love the epicutis serum

  • SA
    Stacy A.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 50-65
    What is your skin type? Normal
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Pigmentation, Wrinkles, Dryness
    Rated 5 out of 5 stars
    1 week ago
    Incredible serum

    The serum was definitely a treat. I added it into my nighttime regiment as my skin was feeling dry at night since starting this serum. I feel like I wake up in my skin is dewier and does not feel dry at all. Some nights, I layer my ISClinical retinol on top of it and other nights I put moisturizer on top of it. Either way in the morning my skin feels really good. It’s definitely pricey, but you don’t need much.

  • HS
    Heidi S.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 18-29
    What is your skin type? Combination
    What is your skin tone? Medium
    What are your skin concerns? Acne, Blemish-prone, Dryness, Oiliness
    Rated 5 out of 5 stars
    1 week ago
    Love

    Love! So hydrating definitely need to be consistent with use to see a difference but it really does add so much moisture to my skin!

  • YB
    Yulissa B.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 40-49
    What is your skin type? Oily
    What is your skin tone? Fair
    What are your skin concerns? Ageing
    Rated 5 out of 5 stars
    1 month ago
    Absolutely love it

    It is worth every penny!

  • KM
    Kristen M.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 40-49
    What is your skin type? Combination
    What is your skin tone? Medium
    What are your skin concerns? Acne, Ageing, Blemish-prone, Sensitivity, Dryness
    Rated 5 out of 5 stars
    2 months ago
    Game changer

    Healed post Accutane atopic dermatitis on my face. Expensive but worth it, fantastic product. I use daily and it’s something that I make sure I never run out of.