Epicutis Lipid Serum

Soothe, Strengthen, and Restore in a Single Step

Formulated with just eight gentle yet powerful ingredients, the Epicutis Lipid Serum is the cornerstone of any healing skincare routine. Powered by a therapeutic concentration of TSC, a patented anti-inflammatory lipid, this silky serum delivers immediate relief for dry, stressed, and post-procedure skin while working over time to calm redness, rebuild the skin barrier, and defend against collagen loss at the cellular level.

Lightweight and fast-absorbing, it melts into the skin with a smooth, non-greasy finish, making it the perfect first step post-cleanse for anyone seeking to restore balance and resilience.

  • Instantly calms inflammation and visibly reduces redness
  • Deeply hydrates and supports the skin’s lipid barrier
  • Helps strengthen skin against environmental stress and collagen breakdown
  • Safe and soothing for sensitive, dry, or post-treatment skin
  • Lasts 3 months when using a pea sized amount twice per day!
Acne Safe
New

Epicutis Lipid Serum

Epicutis Lipid Serum strengthens the skin barrier, calms inflammation, and reduces fine lines—a powerful, lipid-rich serum for healthy, youthful skin.

5.0
Rated 5.0 out of 5 stars
7 Reviews
Regular price $250.00
Unit price
per 
Availability
 
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Compromised Barrier
  • Inflammation
  • Redness/Rosacea
  • Dehydration
Lotion bottle icons

Best For:

  • Dry
  • Normal
  • Oily
  • Combination
  • Sensitive

Epicutis Lipid Serum

Soothe, Strengthen, and Restore in a Single Step

Formulated with just eight gentle yet powerful ingredients, the Epicutis Lipid Serum is the cornerstone of any healing skincare routine. Powered by a therapeutic concentration of TSC, a patented anti-inflammatory lipid, this silky serum delivers immediate relief for dry, stressed, and post-procedure skin while working over time to calm redness, rebuild the skin barrier, and defend against collagen loss at the cellular level.

Lightweight and fast-absorbing, it melts into the skin with a smooth, non-greasy finish, making it the perfect first step post-cleanse for anyone seeking to restore balance and resilience.

  • Instantly calms inflammation and visibly reduces redness
  • Deeply hydrates and supports the skin’s lipid barrier
  • Helps strengthen skin against environmental stress and collagen breakdown
  • Safe and soothing for sensitive, dry, or post-treatment skin
  • Lasts 3 months when using a pea sized amount twice per day!

Essential Additions

Streamlined solutions for maximum results

Epicutis Oil Cleanser - Art of Skin Care

Epicutis Oil Cleanser

$85.00
Unit price
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Epicutis Hyvia Crème - Art of Skin Care

Epicutis Hyvia Crème

$195.00
Unit price
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Epicutis Hydrobiome Mist - Art of Skin Care

Epicutis Hydrobiome Mist

$75.00
Unit price
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Epicutis Lipid Recovery Mask for Eyes - Art of Skin Care

Epicutis Lipid Recovery Mask for Eyes

$105.00
Unit price
per 
5.0
Rated 5.0 out of 5 stars
Based on 7 reviews
Total 5 star reviews: 7 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
7 reviews
  • SA
    Stacy A.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 50-65
    What is your skin type? Normal
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Pigmentation, Wrinkles, Dryness
    Rated 5 out of 5 stars
    22 hours ago
    Incredible serum

    The serum was definitely a treat. I added it into my nighttime regiment as my skin was feeling dry at night since starting this serum. I feel like I wake up in my skin is dewier and does not feel dry at all. Some nights, I layer my ISClinical retinol on top of it and other nights I put moisturizer on top of it. Either way in the morning my skin feels really good. It’s definitely pricey, but you don’t need much.

  • HS
    Heidi S.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 18-29
    What is your skin type? Combination
    What is your skin tone? Medium
    What are your skin concerns? Acne, Blemish-prone, Dryness, Oiliness
    Rated 5 out of 5 stars
    5 days ago
    Love

    Love! So hydrating definitely need to be consistent with use to see a difference but it really does add so much moisture to my skin!

  • YB
    Yulissa B.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 40-49
    What is your skin type? Oily
    What is your skin tone? Fair
    What are your skin concerns? Ageing
    Rated 5 out of 5 stars
    1 month ago
    Absolutely love it

    It is worth every penny!

  • KM
    Kristen M.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 40-49
    What is your skin type? Combination
    What is your skin tone? Medium
    What are your skin concerns? Acne, Ageing, Blemish-prone, Sensitivity, Dryness
    Rated 5 out of 5 stars
    1 month ago
    Game changer

    Healed post Accutane atopic dermatitis on my face. Expensive but worth it, fantastic product. I use daily and it’s something that I make sure I never run out of.

  • MG
    Marci G.
    Verified Buyer
    Reviewing
    Epicutis Lipid Serum
    I recommend this product
    How old are you? 50-65
    What is your skin type? Normal
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Wrinkles
    Rated 5 out of 5 stars
    1 month ago
    Pricey

    The presentation of this product is amazing. However the price point is pretty high. My skin does love it and it feels amazing on my skin. Not sure I’d would repurchase only because of the price. However if my skin was damaged and needed repair and / or relief I would definitely repurchase and feel confident that this product would help