iS Clinical Extra Strength Active Peel System
This professional-grade, two-step botanical peel system delivers 15 at-home treatments designed to exfoliate, brighten, and renew the skin—offering three times the brightening and exfoliating power of the iS Clinical Active Peel System.
Step 1 is an advanced exfoliating formula featuring a potent blend of botanical AHAs, BHAs, and natural extracts to instantly resurface and renew the skin.
Step 2 neutralizes Step 1 while infusing the skin with hydration, antioxidants, and soothing ingredients. It features proprietary Extremozyme® technology to protect DNA, copper peptides to boost healing, and calming botanicals to help strengthen the skin barrier and leave the complexion feeling refreshed and balanced.
2.9 mL each pad | 15 Treatment Sets
- Provides advanced exfoliation
- Brightens pigmentation
- Refines pores
- Improves tone and texture
- Boosts collagen and elastin production
- Reduces appearance of fine lines and wrinkles
- Infuses skin with hydration and antioxidants
In a clinical trial after two weeks:
- 84% of users reported more youthful, luminous looking skin
- 96% of users reported improvements in skin smoothness/texture
- 100% of users reported improvements in oily skin or large pore size
After four weeks:
- 70% of users reported less overall breakouts
- 87% of users reported improvements in unwanted pigmentation
- 90% of users reported a reduction in the appearance of fine lines/wrinkles
*Study completed over a 4 week period of 32 subjects which included use of Cleansing Complex and Eclipse SPF 50+ as part of their regimen throughout the study.
This is a professional-strength brightening peel system. If you're new to peels, we recommend starting with the iS Clinical Active Peel System to help your skin acclimate.
After cleansing, apply Step 1 over entire face and neck and leave on for 3 minutes. DO NOT RINSE. Follow by applying Step 2 over same area, and leave on.
Step 1 and Step 2 will produce a tingling sensation upon application; this is normal.
For optimal results, use every 3-4 days (or as directed by your esthetician), preferably in the evening. Always be sure to apply SPF in the AM when using this product.
- Sugar Cane Extract: Natural source of glycolic acid, provides more gentle exfoliation while also acting as a humectant to hydrate the skin.
- Salicylic Acid: A beta-hydroxy acid that refines texture, clears congested pores, and helps control oil production.
- Willow Bark Extract: A natural form of salicylic acid that exfoliates and refines pores while calming inflammation.
- Bilberry (Vaccinium Myrtillus) Extract: Antioxidant-rich ingredient that gently exfoliates, promotes healthy blood flow, and increases collagen production with calming effects for overall skin health.
- Extremozymes: Proprietary combination of extremophilic enzymes clinically proven to protect and repair DNA in the skin.
- Copper Tripeptide-1: Contains three amino acids (glycine, histidine, and lysine) combined with the mineral copper. Supports healing and regeneration, boosts collagen synthesis, and delivers beneficial epigenetic messages to cells.
- Vitamin C (L-Ascorbic Acid): A powerful antioxidant with anti-inflammatory properties, which helps reduce skin redness, brighten complexion, and even skin tone.
- Imperata Cylindrica Root Extract: Rich in potassium, optimizes and reinforces collagen synthesis and moisture absorption in the skin.
- Colloidal Gold: Formed by suspending small gold particles in liquid so it is biologically usable by the body. Calms inflammation, increases elasticity, and reduces the appearance of fine lines and wrinkles.
- Glutathione: Known to support liver and detoxification, serves as a powerful antioxidant, and helps to brighten the complexion which aids in the appearance of acne scars.
Step 1:
Saccharum Officinarum (Sugarcane) Extract, Alcohol, Water/Aqua/Eau, Propanediol, Hamamelis Virginiana (Witch Hazel) Water, Pentylene Glycol, Citric Acid, Salicylic Acid, Aloe Barbadensis Leaf Juice, Salix Nigra (Willow) Bark Extract, Vaccinium Myrtillus (Bilberry) Fruit Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Citrus Limon (Lemon) Fruit Extract, Camellia Sinensis Leaf Extract, Pyrus Malus (Apple) Fruit Extract, Acer Saccharum (Sugar Maple) Extract, Aminomethyl Propanol, 1,2-Hexanediol, Caprylyl Glycol, Menthol, Fragrance/Parfum, Disodium EDTA
Step 2:
Water/Aqua/Eau, Propanediol, Pentylene Glycol, Scenedesmus Rubescens Extract, Annona Cherimola Fruit Extract, Butylene Glycol, Lentinus Edodes Mycelium Extract, Glycerin, Imperata Cylindrica Root Extract, Maltodextrin, Citrullus Lanatus (Watermelon) Fruit Extract, Pyrus Malus (Apple) Fruit Extract, Leucojum Aestivum Bulb Extract, Lens Esculenta (Lentil) Fruit Extract, Ascorbic Acid, Glycogen, Sodium PCA, Succinic Acid, Glutathione, Tripeptide-1, Gold, Sorbitol, Fragrance/Parfum, PEG-8, 1,2-Hexanediol, Caprylyl Glycol, 1-Methylhydantoin-2-Imide, Sodium Lactate, Dextran, Disodium EDTA, Carbomer, Dipotassium Glycyrrhizate, Xanthan Gum
*While no towelettes are flushable, Extra Strength Active Peel Brightening System towelettes offer a biodegradable solution to plastic-based options and break down safely into the earth. These towelettes are soft and gentle to the skin, made from sustainably sourced bamboo, and are environmentally friendly.
Introducing the newest peel from IS Clinical, a professional-grade two-step system that resurfaces, hydrates, and improves the appearance of fine lines, pigmentation, and texture!
- Unit price
- /per

Primary Concerns:
- Acne
- Dullness
- Fine Lines
- Large Pores
- Loss of Firmness
- Pigmentation
- Wrinkles
- Rough Texture

Best For:
- Dry
- Normal
- Oily
- Combination
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iS Clinical Extra Strength Active Peel System
This professional-grade, two-step botanical peel system delivers 15 at-home treatments designed to exfoliate, brighten, and renew the skin—offering three times the brightening and exfoliating power of the iS Clinical Active Peel System.
Step 1 is an advanced exfoliating formula featuring a potent blend of botanical AHAs, BHAs, and natural extracts to instantly resurface and renew the skin.
Step 2 neutralizes Step 1 while infusing the skin with hydration, antioxidants, and soothing ingredients. It features proprietary Extremozyme® technology to protect DNA, copper peptides to boost healing, and calming botanicals to help strengthen the skin barrier and leave the complexion feeling refreshed and balanced.
2.9 mL each pad | 15 Treatment Sets
- Provides advanced exfoliation
- Brightens pigmentation
- Refines pores
- Improves tone and texture
- Boosts collagen and elastin production
- Reduces appearance of fine lines and wrinkles
- Infuses skin with hydration and antioxidants
In a clinical trial after two weeks:
- 84% of users reported more youthful, luminous looking skin
- 96% of users reported improvements in skin smoothness/texture
- 100% of users reported improvements in oily skin or large pore size
After four weeks:
- 70% of users reported less overall breakouts
- 87% of users reported improvements in unwanted pigmentation
- 90% of users reported a reduction in the appearance of fine lines/wrinkles
*Study completed over a 4 week period of 32 subjects which included use of Cleansing Complex and Eclipse SPF 50+ as part of their regimen throughout the study.
This is a professional-strength brightening peel system. If you're new to peels, we recommend starting with the iS Clinical Active Peel System to help your skin acclimate.
After cleansing, apply Step 1 over entire face and neck and leave on for 3 minutes. DO NOT RINSE. Follow by applying Step 2 over same area, and leave on.
Step 1 and Step 2 will produce a tingling sensation upon application; this is normal.
For optimal results, use every 3-4 days (or as directed by your esthetician), preferably in the evening. Always be sure to apply SPF in the AM when using this product.
- Sugar Cane Extract: Natural source of glycolic acid, provides more gentle exfoliation while also acting as a humectant to hydrate the skin.
- Salicylic Acid: A beta-hydroxy acid that refines texture, clears congested pores, and helps control oil production.
- Willow Bark Extract: A natural form of salicylic acid that exfoliates and refines pores while calming inflammation.
- Bilberry (Vaccinium Myrtillus) Extract: Antioxidant-rich ingredient that gently exfoliates, promotes healthy blood flow, and increases collagen production with calming effects for overall skin health.
- Extremozymes: Proprietary combination of extremophilic enzymes clinically proven to protect and repair DNA in the skin.
- Copper Tripeptide-1: Contains three amino acids (glycine, histidine, and lysine) combined with the mineral copper. Supports healing and regeneration, boosts collagen synthesis, and delivers beneficial epigenetic messages to cells.
- Vitamin C (L-Ascorbic Acid): A powerful antioxidant with anti-inflammatory properties, which helps reduce skin redness, brighten complexion, and even skin tone.
- Imperata Cylindrica Root Extract: Rich in potassium, optimizes and reinforces collagen synthesis and moisture absorption in the skin.
- Colloidal Gold: Formed by suspending small gold particles in liquid so it is biologically usable by the body. Calms inflammation, increases elasticity, and reduces the appearance of fine lines and wrinkles.
- Glutathione: Known to support liver and detoxification, serves as a powerful antioxidant, and helps to brighten the complexion which aids in the appearance of acne scars.
Step 1:
Saccharum Officinarum (Sugarcane) Extract, Alcohol, Water/Aqua/Eau, Propanediol, Hamamelis Virginiana (Witch Hazel) Water, Pentylene Glycol, Citric Acid, Salicylic Acid, Aloe Barbadensis Leaf Juice, Salix Nigra (Willow) Bark Extract, Vaccinium Myrtillus (Bilberry) Fruit Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Citrus Limon (Lemon) Fruit Extract, Camellia Sinensis Leaf Extract, Pyrus Malus (Apple) Fruit Extract, Acer Saccharum (Sugar Maple) Extract, Aminomethyl Propanol, 1,2-Hexanediol, Caprylyl Glycol, Menthol, Fragrance/Parfum, Disodium EDTA
Step 2:
Water/Aqua/Eau, Propanediol, Pentylene Glycol, Scenedesmus Rubescens Extract, Annona Cherimola Fruit Extract, Butylene Glycol, Lentinus Edodes Mycelium Extract, Glycerin, Imperata Cylindrica Root Extract, Maltodextrin, Citrullus Lanatus (Watermelon) Fruit Extract, Pyrus Malus (Apple) Fruit Extract, Leucojum Aestivum Bulb Extract, Lens Esculenta (Lentil) Fruit Extract, Ascorbic Acid, Glycogen, Sodium PCA, Succinic Acid, Glutathione, Tripeptide-1, Gold, Sorbitol, Fragrance/Parfum, PEG-8, 1,2-Hexanediol, Caprylyl Glycol, 1-Methylhydantoin-2-Imide, Sodium Lactate, Dextran, Disodium EDTA, Carbomer, Dipotassium Glycyrrhizate, Xanthan Gum
*While no towelettes are flushable, Extra Strength Active Peel Brightening System towelettes offer a biodegradable solution to plastic-based options and break down safely into the earth. These towelettes are soft and gentle to the skin, made from sustainably sourced bamboo, and are environmentally friendly.






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iS Clinical Extra Strength Active Peel System
- MVMelissa V.Verified BuyerReviewingiS Clinical Extra Strength Active Peel SystemI recommend this productHow old are you? 50-65What is your skin type? NormalWhat is your skin tone? MediumWhat are your skin concerns? AgeingRated 5 out of 5 stars3 days agoNoticeable Results
I've been using and loving the iS Clinical Active Peel System for over a year so I was very excited to try the Extra Strength Peel System. This peel is next level of strength. Definitely spicier than the original but worth the results. I experienced some peeling after the first few applications but nothing too drastic. I am loving the results. My skin looks brighter, feels smoother, and dark spots are fading. Very happy with the treatments and look forward to future results with continued use. Hoping there will be another community Peel-A-Thon in the near future with the Extra Strength!
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Why Art of Skin Care?
At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.
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