iS Clinical Active Serum is a lightweight, multi-tasking botanical serum that addresses blemishes, fine lines, and uneven skin tone within a single clarifying formula. It carries a clean, subtle menthol scent and a cooling sensation on application, with a skin-compatible pH of 5.6 that works with your barrier rather than against it. The formula draws on botanical sources of both glycolic and salicylic acid, pairing them with brightening, collagen-supporting, and hydrating ingredients to deliver real results across multiple skin concerns at once.

Key Benefits

Dual-acid exfoliation that clears pores and smooths texture Sugarcane extract delivers glycolic acid and willow bark extract provides salicylic acid, working together to dissolve surface buildup, decongest pores, and refine rough skin without the irritation of synthetic acid concentrations.

Reduces blemishes and keeps skin clear Salicylic acid from willow bark penetrates into pores to dissolve oil and debris, making this an effective daily option for acne-prone skin that still wants a gentle touch.

Softens fine lines and supports collagen Mushroom extract (polyporus umbellatus) and bilberry (vaccinium myrtillus) encourage collagen synthesis and cell renewal, visibly reducing the appearance of fine lines with continued use.

Fades discoloration and evens tone Arbutin works to inhibit melanin production and fade post-inflammatory hyperpigmentation, helping skin look more uniform and consistent in tone over time.

Supports moisture retention and barrier resilience Glycerin and mushroom extract work together to reinforce the skin's moisture barrier, keeping skin hydrated, firm, and balanced even as the exfoliating actives do their work.

Clinically Proven Results (3 months/using twice daily in combination with Cleansing Complex):

• 94% improvement in active acne
• 83% improvement in acne scars
• 82% improvement in appearance of pore size
• 73% improvement in skin texture
• 64% improvement in fine lines and wrinkles
• 56% improvement in pigment irregularities

If your skin is dealing with breakouts and fine lines at the same time, iS Clinical Active Serum is built for exactly that. It's ideal for combination, oily, or acne-prone skin types who want the clarifying power of salicylic and glycolic acid alongside real anti-aging support, without having to layer multiple treatment products.

It's also a strong fit for anyone working through uneven skin tone, enlarged pores, rough texture, or post-acne discoloration. The botanical delivery of both exfoliating acids makes it more tolerable than many traditional acid treatments, though those with sensitive skin may want to ease in slowly and monitor their response to the menthol cooling sensation.

If you're looking to simplify your routine without trading down on results, this serum covers a lot of ground in one step.

The menthol in this serum creates a noticeable tingling sensation that tells you it's working, but if you find it too intense at first, try warming one to two drops between your palms before pressing them gently onto skin rather than spreading the serum directly. This slows the delivery slightly and makes the initial adjustment period more comfortable.

Prepare: Cleanse and tone skin, then allow it to dry completely before applying.

Apply: Dispense 3 to 5 drops and spread evenly over face, neck, and chest.

Frequency: Begin with once daily use and increase to twice daily as your skin adjusts. Always follow morning use with a broad-spectrum SPF, as exfoliating acids increase sensitivity to UV exposure.