Circadia Serum 71 Renewal Serum 0.5 fl oz (15ml) - deep blue frosted glass dropper bottle

Circadia Serum 71 Renewal Serum close-up texture swatch showing lightweight clear gel with a soft silver tone and micro-bubbles

Hand dispensing Circadia Serum 71 Renewal Serum from dropper bottle, a high-performance brightening serum that improves tone, reduces redness, and boosts collagen and elastin for firmer skin

Circadia Serum 71 Renewal Serum dropper bottle with key ingredients: Tranexamic Acid to fade dark spots and even tone, Azelaic Acid to reduce redness and acne, Mandelic Acid to refine texture, CM-Glucan Forte to support healing, and NeoDermyl peptide for firming and elasticity

Woman with even radiant skin showing Circadia Serum 71 Renewal Serum is best for hyperpigmented, red and sensitive, acne-prone, and aging or dull skin

Five-star verified customer review for Circadia Serum 71 Renewal Serum praising its ability to reduce breakouts, even skin tone, and reduce redness

Acne Safe

Circadia Serum 71

Name: Circadia Serum 71
Brand: Circadia
SKU: CIR004155

Circadia

A brightening serum with tranexamic acid to fade dark spots, smooth texture, calm breakouts, and firm skin in one evening step.

5.0

Rated 5.0 out of 5 stars

16 Reviews

Size: 0.5 oz

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Circadia Serum 71 is a multitasking treatment serum that targets hyperpigmentation, adult acne, uneven texture, and early loss of firmness in a single evening step. Built around a trio of clinically recognized brightening acids, 2% tranexamic acid, 5% mandelic acid, and 0.3% azelaic acid, it addresses the full spectrum of pigment and breakout concerns while remaining gentle enough for sensitive skin. This serum is fragrance-free.
Key Benefits
Fades Dark Spots and Melasma Transexamic acid works at 2% to interrupt the signaling pathways that trigger excess melanin production, making it one of the most effective non-hydroquinone options for melasma and stubborn post-acne marks.
Gently Exfoliates and Clears Pores Mandelic acid at 5% delivers controlled exfoliation with a larger molecular size than most acids, meaning it penetrates more slowly and is less likely to cause irritation while still refining texture and keeping pores clear.
Controls Redness and Breakouts Azelaic acid at 0.3% supports the formula's acne-fighting action by calming inflammation and reducing the presence of acne-causing bacteria, making it particularly useful for adult acne and rosacea-prone skin.
Firms and Supports Collagen Production Neodermyl, a next-generation copper peptide complex present as copper lysinate/prolinate and methylglucoside phosphate, is clinically recognized to stimulate collagen and elastin synthesis, improving skin density and elasticity over time.
Calms Inflammation and Strengthens the Barrier Magnesium carboxymethyl beta-glucan, the active form of CM-Glucan Forte, helps neutralize inflammation and reinforce the skin barrier, making this formula well-suited for reactive and sensitive skin types.
Circadia Serum 71 is suitable for all skin types, including sensitive, oily, combination, and mature skin. Its non-inflammatory formula is designed to deliver real brightening and firming results without the irritation, peeling, or redness that often comes with traditional acid treatments or peels.
This serum is especially well-matched for anyone dealing with melasma, post-inflammatory hyperpigmentation, adult acne, or early skin laxity. Because it addresses multiple concerns in one formula, it is a practical choice for those who want to simplify their routine without sacrificing results.
It also works well as a maintenance step between professional chemical peels or enzyme treatments, helping to extend and protect the results you get in the treatment room.
Start with three evenings per week during your first two weeks to allow your skin to acclimate, then gradually build toward nightly use. Because tranexamic acid, mandelic acid, and azelaic acid are all working together overnight, consistency matters more than frequency at the start. Patience in the adjustment period is what leads to the clearest, most even results long term.
Prepare: Cleanse and lightly mist skin.
Apply: Dispense 3 to 5 drops into your fingertips.
Technique: Press gently into the face, neck, and chest.
Follow: Layer a moisturizer over the serum to seal in hydration.
Frequency: Begin with 3 times per week for the first two weeks, then increase to nightly as tolerated. Always apply SPF the following morning.
Key Ingredients

Tranexamic Acid: Derived from an essential amino acid, this mega-brightening ingredient possesses potent anti-inflammatory properties and inhibits pigment formation while fading current dark spots as well.
Mandelic Acid: An alpha-hydroxy acid that brightens, suppresses hyperpigmentation, and enhances cell turnover.
Azelaic Acid: Gently clears pores of bacteria while diminishing hyperpigmentation by reducing melanin production and calming inflammation.
Neodermyl®: A copper-based peptide that accelerates wound healing and cell regeneration while stimulating collagen and elastin for firming benefits.
CM-Glucan Forte: A stabilized form of beta-glucan that rebalances the skin's immune system, soothes irritation, and strengthens the skin barrier.

Aqua/Water, Propanediol, Mandelic Acid, Butylene Glycol, Tranexamic Acid, Phenoxyethanol, Sodium PCA, Hydroxyethylcellulose, Sodium Hydroxide, Azelaic Acid, Glycerin, Magnesium Carboxymethyl Beta-Glucan, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Alcohol, Sodium Hydroxide.
What skin concerns does Circadia Serum 71 address?

Circadia Serum 71 is formulated to treat hyperpigmentation, melasma, post-acne dark spots (PIH), adult acne, redness, uneven texture, and early skin laxity in one formula. The combination of tranexamic acid, mandelic acid, azelaic acid, and Neodermyl copper peptide makes it one of the more comprehensive single-step evening treatments available. It is designed for those who want to address both pigment and firmness without stacking multiple products.

Is Circadia Serum 71 effective for melasma?

Yes. Circadia Serum 71 contains 2% tranexamic acid, which works by blocking the communication between UV-damaged skin cells and the melanocytes that produce pigment. This makes it a well-supported, non-hydroquinone option for both melasma and stubborn dark patches. Consistent evening use is key, and pairing it with a broad-spectrum SPF each morning will help prevent new pigmentation from forming.

Is Circadia Serum 71 safe for acne-prone skin?

Yes. The 5% mandelic acid in Circadia Serum 71 has natural antibacterial properties and a larger molecular structure than many other AHAs, making it effective without being harsh on breakout-prone skin. The 0.3% azelaic acid adds anti-inflammatory and pore-clarifying support. Together, these actives help reduce active breakouts and fade the dark marks they leave behind.

Will Circadia Serum 71 cause visible peeling or flaking?

Most users do not experience visible peeling with Circadia Serum 71. The mandelic acid exfoliates at a cellular level rather than causing surface flaking, which means texture improvement happens without obvious downtime. If you are new to acid serums or have very sensitive skin, starting with three evenings per week gives your skin time to adjust comfortably.

Can Circadia Serum 71 be used alongside retinol?

Yes, but not on the same night. Alternating evenings is the safest approach: use Circadia Serum 71 on one night and your retinol on the next. This prevents cumulative irritation from layering two exfoliating actives and allows each ingredient to work effectively without compromising your barrier.

Is Circadia Serum 71 appropriate for sensitive skin?

Yes. Circadia Serum 71 includes magnesium carboxymethyl beta-glucan, the active component of CM-Glucan Forte, which helps calm inflammation and reinforce the skin barrier. This makes the formula considerably more tolerable than traditional acid treatments for those with sensitivity or reactive skin. Starting at a lower frequency and building up gradually further reduces the likelihood of irritation.

How long does it take to see results from Circadia Serum 71?

Many users notice smoother texture and a more even skin tone within the first one to two weeks of consistent use. Fading of deeper pigmentation, melasma, and visible improvement in firmness typically become apparent between four and eight weeks. Because Neodermyl works by stimulating collagen and elastin production, the firming benefits build gradually and tend to become more noticeable over time.

Why buy Circadia Serum 71 from Art of Skin Care?

Art of Skin Care is an authorized retailer of Circadia, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if Circadia Serum 71 is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.

Learn More

Circadia Serum 71 is a multitasking treatment serum that targets hyperpigmentation, adult acne, uneven texture, and early loss of firmness in a single evening step. Built around a trio of clinically recognized brightening acids, 2% tranexamic acid, 5% mandelic acid, and 0.3% azelaic acid, it addresses the full spectrum of pigment and breakout concerns while remaining gentle enough for sensitive skin. This serum is fragrance-free.

Key Benefits

Fades Dark Spots and Melasma Transexamic acid works at 2% to interrupt the signaling pathways that trigger excess melanin production, making it one of the most effective non-hydroquinone options for melasma and stubborn post-acne marks.

Gently Exfoliates and Clears Pores Mandelic acid at 5% delivers controlled exfoliation with a larger molecular size than most acids, meaning it penetrates more slowly and is less likely to cause irritation while still refining texture and keeping pores clear.

Controls Redness and Breakouts Azelaic acid at 0.3% supports the formula's acne-fighting action by calming inflammation and reducing the presence of acne-causing bacteria, making it particularly useful for adult acne and rosacea-prone skin.

Firms and Supports Collagen Production Neodermyl, a next-generation copper peptide complex present as copper lysinate/prolinate and methylglucoside phosphate, is clinically recognized to stimulate collagen and elastin synthesis, improving skin density and elasticity over time.

Calms Inflammation and Strengthens the Barrier Magnesium carboxymethyl beta-glucan, the active form of CM-Glucan Forte, helps neutralize inflammation and reinforce the skin barrier, making this formula well-suited for reactive and sensitive skin types.

Who it's For

Esthetician Recommendations

How to Use

Ingredients

Frequently Asked Questions

What skin concerns does Circadia Serum 71 address?

Circadia Serum 71 is formulated to treat hyperpigmentation, melasma, post-acne dark spots (PIH), adult acne, redness, uneven texture, and early skin laxity in one formula. The combination of tranexamic acid, mandelic acid, azelaic acid, and Neodermyl copper peptide makes it one of the more comprehensive single-step evening treatments available. It is designed for those who want to address both pigment and firmness without stacking multiple products.

Is Circadia Serum 71 effective for melasma?

Yes. Circadia Serum 71 contains 2% tranexamic acid, which works by blocking the communication between UV-damaged skin cells and the melanocytes that produce pigment. This makes it a well-supported, non-hydroquinone option for both melasma and stubborn dark patches. Consistent evening use is key, and pairing it with a broad-spectrum SPF each morning will help prevent new pigmentation from forming.

Is Circadia Serum 71 safe for acne-prone skin?

Yes. The 5% mandelic acid in Circadia Serum 71 has natural antibacterial properties and a larger molecular structure than many other AHAs, making it effective without being harsh on breakout-prone skin. The 0.3% azelaic acid adds anti-inflammatory and pore-clarifying support. Together, these actives help reduce active breakouts and fade the dark marks they leave behind.

Will Circadia Serum 71 cause visible peeling or flaking?

Most users do not experience visible peeling with Circadia Serum 71. The mandelic acid exfoliates at a cellular level rather than causing surface flaking, which means texture improvement happens without obvious downtime. If you are new to acid serums or have very sensitive skin, starting with three evenings per week gives your skin time to adjust comfortably.

Can Circadia Serum 71 be used alongside retinol?

Yes, but not on the same night. Alternating evenings is the safest approach: use Circadia Serum 71 on one night and your retinol on the next. This prevents cumulative irritation from layering two exfoliating actives and allows each ingredient to work effectively without compromising your barrier.

Is Circadia Serum 71 appropriate for sensitive skin?

Yes. Circadia Serum 71 includes magnesium carboxymethyl beta-glucan, the active component of CM-Glucan Forte, which helps calm inflammation and reinforce the skin barrier. This makes the formula considerably more tolerable than traditional acid treatments for those with sensitivity or reactive skin. Starting at a lower frequency and building up gradually further reduces the likelihood of irritation.

How long does it take to see results from Circadia Serum 71?

Many users notice smoother texture and a more even skin tone within the first one to two weeks of consistent use. Fading of deeper pigmentation, melasma, and visible improvement in firmness typically become apparent between four and eight weeks. Because Neodermyl works by stimulating collagen and elastin production, the firming benefits build gradually and tend to become more noticeable over time.

Why buy Circadia Serum 71 from Art of Skin Care?

Art of Skin Care is an authorized retailer of Circadia, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if Circadia Serum 71 is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.