GlyMed Plus Bio Renewal Serum
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GlyMed Plus Bio Renewal Serum is a peptide-rich gel serum designed to accelerate the skin's natural renewal cycle, refine texture, and restore clarity to dull or aging skin. At the heart of this formula is Hexanoyl Dipeptide-3 Norleucine Acetate, a specialized multi-functional peptide that works by mimicking the skin's natural exfoliation signal, encouraging the release of dead, damaged cells while supporting re-densification of the skin's structure from within. The formula carries a soft, subtle luminosity from mica with warm yellow undertones, which visually neutralizes purplish or sallow discoloration while the actives work beneath the surface.
Key Benefits
Accelerates Cell Renewal Hexanoyl Dipeptide-3 Norleucine Acetate mimics the skin's own exfoliation signals, prompting the shedding of damaged surface cells and speeding up cellular turnover for a visibly more even, refined complexion.
Firms and Re-Densifies Skin Structure Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, a peptide pair clinically studied under the trade name Matrixyl 3000, work together to support collagen synthesis and help restore the skin's structural density, reducing the appearance of fine lines and wrinkles.
Relaxes Expression Lines Acetyl Hexapeptide-8 targets the repetitive muscle contractions that deepen dynamic lines around the eyes, forehead, and mouth, softening their appearance with consistent use.
Delivers Lasting Hydration Sodium hyaluronate draws moisture into the skin while panthenol and glycerin reinforce the barrier and help skin hold that hydration throughout the day.
Brightens and Defends Against Oxidative Stress Tetrahexyldecyl ascorbate, a highly stable, oil-soluble form of vitamin C, works alongside green tea leaf extract and grape seed extract to neutralize free radical damage and support a more even, luminous skin tone.
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If your skin has started to look dull, feel rough in texture, or show the early signs of aging like fine lines, uneven tone, or a loss of firmness, this serum was formulated for you. It works best for normal, dry, combination, and mature skin types looking to accelerate their skin's natural renewal without the irritation that often comes with exfoliating acids.
This is also an excellent option for anyone whose skin has become congested with damaged or stagnant surface cells but cannot tolerate glycolic or lactic acid. Because the exfoliation mechanism here is peptide-driven rather than acid-driven, it is suitable for sensitive skin types who still want measurable results.
If you are dealing with pigmentation concerns, early texture changes, or a complexion that has lost its clarity over time, the combination of cellular renewal peptides, stable vitamin C, and antioxidant botanicals in this formula addresses the issue from multiple angles.
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Layer this serum directly under your moisturizer at night and, on days when you plan to wear makeup, you can use it as a morning base as well. The mica in the formula has warm yellow undertones that visually cancel out purplish or grayish discoloration in the skin, so it does double duty while the peptides work beneath the surface.
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Cleanse and tone your skin as usual before applying.
Apply one pump to the face, neck, and chest.
Technique Press and smooth gently into skin, allowing the serum to absorb before layering your moisturizer on top.
Frequency Use in the evening. Apply a broad-spectrum SPF every morning while using this serum.
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Key Ingredients
- Hexanoyl Dipeptide-3 Norleucine Acetate: This tripeptide is specially targeted to increase cell turnover and the skin shedding process to renew tone and texture.
- Palmitoyl Tripeptide-1: Stimulates production of collagen, elastin, and hyaluronic acid, with a proven lifting effect and reduction of wrinkle volume.
- Palmitoyl Tetrapeptide-7: A soothing peptide that helps reduce inflammation and supports the breakdown of blood-derived pigments under the eyes, visibly diminishing dark circles and promoting a brighter, more even-toned appearance.
- Argireline (Acetyl Hexapeptide-8): A powerful peptide that inhibits wrinkle formation with a relaxing effect on facial expression muscles.
- Copper Tripeptide-1: Contains three amino acids (glycine, histidine, and lysine) combined with the mineral copper. Supports healing and regeneration, boosts collagen synthesis, and delivers beneficial epigenetic messages to cells.
- Green Tea Extract: Calms, soothes, and moisturizes, while providing antioxidant and anti-microbial support.
- Proprietary Fruit Blend (cranberry, papaya, and pineapple): These active fruit enzymes are high in antioxidants and provide gentle exfoliation, unclogging the pores and brightening the skin for an overall refreshed appearance.
Water, Acetyl Hexapeptide-8, Glycerin, Polysorbate 20, Pentylene Glycol, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Hexanoyl Dipeptide-3 Norleucine Acetate, Panthenol, Glycine, Sorbitol, Dimethyl Mea, Hydrolyzed Soy Protein, Propanediol, Butylene Glycol, Mucor Miehei Extract, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Olea Europaea (Olive) Leaf Extract, Carica Papaya Fruit Extract, Citrus Limon (Lemon) Peel Oil, Moringa Oleifera Seed Oil, Vitis Vinifera (Grape) Seed Oil, Citrus Aurantifolia (Lime) Peel Oil, Tocopherol, Tetrahexyldecyl Ascorbate, Lecithin, Carbomer, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Mica, Titanium Dioxide, Blue 1, Yellow 5
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What makes GlyMed Plus Bio Renewal Serum different from a traditional exfoliating serum?
Most exfoliating serums rely on acids like glycolic or lactic acid to dissolve the bonds between dead skin cells. GlyMed Plus Bio Renewal Serum uses Hexanoyl Dipeptide-3 Norleucine Acetate, a peptide that signals the skin to initiate its own natural shedding process instead of chemically dissolving surface cells. This makes it a gentler, more biomimetic approach to cellular renewal, with less risk of irritation, sensitivity, or disruption to the skin barrier.
Which peptides are in GlyMed Plus Bio Renewal Serum and what does each one do?
The formula contains four distinct peptides, each targeting a different function. Hexanoyl Dipeptide-3 Norleucine Acetate drives cellular renewal by mimicking the skin's natural exfoliation signal. Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 support collagen synthesis and help restore firmness and skin density. Acetyl Hexapeptide-8 relaxes the repetitive muscle contractions responsible for expression lines. Together, they create a multi-layered approach to skin renewal that a single-peptide formula cannot match.
Is GlyMed Plus Bio Renewal Serum safe for sensitive skin?
Yes, it is a good fit for sensitive skin that still wants renewal results. Because the exfoliation mechanism is driven by peptides rather than acids, there is no risk of the pH-related irritation that acid-based exfoliants can cause. Copper Tripeptide-1 in the formula also has known skin-calming and regenerative properties that support the skin's barrier during the renewal process.
What form of vitamin C does GlyMed Plus Bio Renewal Serum contain?
The formula uses tetrahexyldecyl ascorbate, which is an oil-soluble, highly stable ester form of vitamin C. Unlike L-ascorbic acid, it does not oxidize quickly on contact with air or light, making it significantly more shelf-stable. It penetrates effectively into the skin and converts to active vitamin C once absorbed, where it works to neutralize free radicals and support a more even, clearer tone.
Can GlyMed Plus Bio Renewal Serum be used in the morning as well as at night?
The recommended use is in the evening, and that is when the peptides can work most effectively alongside the skin's natural overnight renewal cycle. However, because the formula does not contain exfoliating acids or retinoids, it is not inherently photosensitizing. If you choose to use it in the morning, apply a broad-spectrum SPF afterward to protect the skin and support the brightening results the vitamin C and antioxidants in the formula are working toward.
What antioxidant ingredients are included in GlyMed Plus Bio Renewal Serum?
The formula includes green tea leaf extract, grape seed extract, olive leaf extract, and tocopherol, a form of vitamin E, alongside tetrahexyldecyl ascorbate. Together, they provide multi-pathway antioxidant protection against environmental damage, which is one of the primary drivers of uneven tone, dullness, and accelerated skin aging. Moringa oleifera seed oil adds additional protective and nourishing properties to the formula.
How long before results are visible with GlyMed Plus Bio Renewal Serum?
Because this serum works by supporting the skin's natural cellular turnover rather than forcing surface exfoliation, results build gradually. Most users begin to notice improved texture and a clearer, more even tone within four to six weeks of consistent nightly use. Firmness and visible reduction in fine lines typically become more apparent after eight to twelve weeks, as collagen-supporting peptides require sustained use to show structural changes.
Why buy GlyMed Plus Bio Renewal Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of GlyMed Plus, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if GlyMed Plus Bio Renewal Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
GlyMed Plus Bio Renewal Serum is a peptide-rich gel serum designed to accelerate the skin's natural renewal cycle, refine texture, and restore clarity to dull or aging skin. At the heart of this formula is Hexanoyl Dipeptide-3 Norleucine Acetate, a specialized multi-functional peptide that works by mimicking the skin's natural exfoliation signal, encouraging the release of dead, damaged cells while supporting re-densification of the skin's structure from within. The formula carries a soft, subtle luminosity from mica with warm yellow undertones, which visually neutralizes purplish or sallow discoloration while the actives work beneath the surface.
Key Benefits
Accelerates Cell Renewal Hexanoyl Dipeptide-3 Norleucine Acetate mimics the skin's own exfoliation signals, prompting the shedding of damaged surface cells and speeding up cellular turnover for a visibly more even, refined complexion.
Firms and Re-Densifies Skin Structure Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, a peptide pair clinically studied under the trade name Matrixyl 3000, work together to support collagen synthesis and help restore the skin's structural density, reducing the appearance of fine lines and wrinkles.
Relaxes Expression Lines Acetyl Hexapeptide-8 targets the repetitive muscle contractions that deepen dynamic lines around the eyes, forehead, and mouth, softening their appearance with consistent use.
Delivers Lasting Hydration Sodium hyaluronate draws moisture into the skin while panthenol and glycerin reinforce the barrier and help skin hold that hydration throughout the day.
Brightens and Defends Against Oxidative Stress Tetrahexyldecyl ascorbate, a highly stable, oil-soluble form of vitamin C, works alongside green tea leaf extract and grape seed extract to neutralize free radical damage and support a more even, luminous skin tone.
If your skin has started to look dull, feel rough in texture, or show the early signs of aging like fine lines, uneven tone, or a loss of firmness, this serum was formulated for you. It works best for normal, dry, combination, and mature skin types looking to accelerate their skin's natural renewal without the irritation that often comes with exfoliating acids.
This is also an excellent option for anyone whose skin has become congested with damaged or stagnant surface cells but cannot tolerate glycolic or lactic acid. Because the exfoliation mechanism here is peptide-driven rather than acid-driven, it is suitable for sensitive skin types who still want measurable results.
If you are dealing with pigmentation concerns, early texture changes, or a complexion that has lost its clarity over time, the combination of cellular renewal peptides, stable vitamin C, and antioxidant botanicals in this formula addresses the issue from multiple angles.
Layer this serum directly under your moisturizer at night and, on days when you plan to wear makeup, you can use it as a morning base as well. The mica in the formula has warm yellow undertones that visually cancel out purplish or grayish discoloration in the skin, so it does double duty while the peptides work beneath the surface.
Cleanse and tone your skin as usual before applying.
Apply one pump to the face, neck, and chest.
Technique Press and smooth gently into skin, allowing the serum to absorb before layering your moisturizer on top.
Frequency Use in the evening. Apply a broad-spectrum SPF every morning while using this serum.
- Hexanoyl Dipeptide-3 Norleucine Acetate: This tripeptide is specially targeted to increase cell turnover and the skin shedding process to renew tone and texture.
- Palmitoyl Tripeptide-1: Stimulates production of collagen, elastin, and hyaluronic acid, with a proven lifting effect and reduction of wrinkle volume.
- Palmitoyl Tetrapeptide-7: A soothing peptide that helps reduce inflammation and supports the breakdown of blood-derived pigments under the eyes, visibly diminishing dark circles and promoting a brighter, more even-toned appearance.
- Argireline (Acetyl Hexapeptide-8): A powerful peptide that inhibits wrinkle formation with a relaxing effect on facial expression muscles.
- Copper Tripeptide-1: Contains three amino acids (glycine, histidine, and lysine) combined with the mineral copper. Supports healing and regeneration, boosts collagen synthesis, and delivers beneficial epigenetic messages to cells.
- Green Tea Extract: Calms, soothes, and moisturizes, while providing antioxidant and anti-microbial support.
- Proprietary Fruit Blend (cranberry, papaya, and pineapple): These active fruit enzymes are high in antioxidants and provide gentle exfoliation, unclogging the pores and brightening the skin for an overall refreshed appearance.
Water, Acetyl Hexapeptide-8, Glycerin, Polysorbate 20, Pentylene Glycol, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Hexanoyl Dipeptide-3 Norleucine Acetate, Panthenol, Glycine, Sorbitol, Dimethyl Mea, Hydrolyzed Soy Protein, Propanediol, Butylene Glycol, Mucor Miehei Extract, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Olea Europaea (Olive) Leaf Extract, Carica Papaya Fruit Extract, Citrus Limon (Lemon) Peel Oil, Moringa Oleifera Seed Oil, Vitis Vinifera (Grape) Seed Oil, Citrus Aurantifolia (Lime) Peel Oil, Tocopherol, Tetrahexyldecyl Ascorbate, Lecithin, Carbomer, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Mica, Titanium Dioxide, Blue 1, Yellow 5
What makes GlyMed Plus Bio Renewal Serum different from a traditional exfoliating serum?
Most exfoliating serums rely on acids like glycolic or lactic acid to dissolve the bonds between dead skin cells. GlyMed Plus Bio Renewal Serum uses Hexanoyl Dipeptide-3 Norleucine Acetate, a peptide that signals the skin to initiate its own natural shedding process instead of chemically dissolving surface cells. This makes it a gentler, more biomimetic approach to cellular renewal, with less risk of irritation, sensitivity, or disruption to the skin barrier.
Which peptides are in GlyMed Plus Bio Renewal Serum and what does each one do?
The formula contains four distinct peptides, each targeting a different function. Hexanoyl Dipeptide-3 Norleucine Acetate drives cellular renewal by mimicking the skin's natural exfoliation signal. Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 support collagen synthesis and help restore firmness and skin density. Acetyl Hexapeptide-8 relaxes the repetitive muscle contractions responsible for expression lines. Together, they create a multi-layered approach to skin renewal that a single-peptide formula cannot match.
Is GlyMed Plus Bio Renewal Serum safe for sensitive skin?
Yes, it is a good fit for sensitive skin that still wants renewal results. Because the exfoliation mechanism is driven by peptides rather than acids, there is no risk of the pH-related irritation that acid-based exfoliants can cause. Copper Tripeptide-1 in the formula also has known skin-calming and regenerative properties that support the skin's barrier during the renewal process.
What form of vitamin C does GlyMed Plus Bio Renewal Serum contain?
The formula uses tetrahexyldecyl ascorbate, which is an oil-soluble, highly stable ester form of vitamin C. Unlike L-ascorbic acid, it does not oxidize quickly on contact with air or light, making it significantly more shelf-stable. It penetrates effectively into the skin and converts to active vitamin C once absorbed, where it works to neutralize free radicals and support a more even, clearer tone.
Can GlyMed Plus Bio Renewal Serum be used in the morning as well as at night?
The recommended use is in the evening, and that is when the peptides can work most effectively alongside the skin's natural overnight renewal cycle. However, because the formula does not contain exfoliating acids or retinoids, it is not inherently photosensitizing. If you choose to use it in the morning, apply a broad-spectrum SPF afterward to protect the skin and support the brightening results the vitamin C and antioxidants in the formula are working toward.
What antioxidant ingredients are included in GlyMed Plus Bio Renewal Serum?
The formula includes green tea leaf extract, grape seed extract, olive leaf extract, and tocopherol, a form of vitamin E, alongside tetrahexyldecyl ascorbate. Together, they provide multi-pathway antioxidant protection against environmental damage, which is one of the primary drivers of uneven tone, dullness, and accelerated skin aging. Moringa oleifera seed oil adds additional protective and nourishing properties to the formula.
How long before results are visible with GlyMed Plus Bio Renewal Serum?
Because this serum works by supporting the skin's natural cellular turnover rather than forcing surface exfoliation, results build gradually. Most users begin to notice improved texture and a clearer, more even tone within four to six weeks of consistent nightly use. Firmness and visible reduction in fine lines typically become more apparent after eight to twelve weeks, as collagen-supporting peptides require sustained use to show structural changes.
Why buy GlyMed Plus Bio Renewal Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of GlyMed Plus, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if GlyMed Plus Bio Renewal Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
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GlyMed Plus Bio Renewal Serum
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- KUKaren U.Verified BuyerReviewingGlyMed Plus Bio Renewal SerumI recommend this productHow old are you? 50-65What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Ageing, Pigmentation, Wrinkles, Sun DamageRated 5 out of 5 stars1 year agoGreat way to end Jeana's skin cycling routine...
I use this on day 4 of my skin cycling. It make my skin soft and plump!
Was this helpful? - MVMelissa V.Verified BuyerReviewingGlyMed Plus Bio Renewal SerumI recommend this productHow old are you? 50-65What is your skin type? CombinationWhat is your skin tone? FairRated 5 out of 5 stars1 year agoRenewing serum
This is a great new addition to my evening skin cycling routine. This serum is a part of my nourishing nights. I think it helps elevate the results.
Was this helpful? - SShelleyReviewingGlyMed Plus Bio Renewal SerumI recommend this productRated 5 out of 5 stars1 year ago5 Stars
I love the smell of this serum.
Was this helpful? - KGKalin G.Verified BuyerReviewingGlyMed Plus Bio Renewal SerumI recommend this productHow old are you? 30-39What are your skin concerns? Blemish-proneRated 5 out of 5 stars1 year agoGlyMed Plus Bio Renewal Serum
Best serum I've ever used
My new go to night serum. I have a noticeable difference just after one use. Less redness, smaller pores.
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