Most vitamin C serums deliver antioxidant protection and brightening through ascorbic acid alone. iS Clinical GeneXC Serum goes further by combining ascorbic acid with Extremozymes, a proprietary blend of DNA-repairing enzymes that protect and restore cellular integrity damaged by UV and environmental exposure. This means the serum is not just defending your skin in the moment but actively supporting its ability to repair itself at a cellular level for longer-term results.

Yes. The plankton extract in iS Clinical GeneXC Serum is lab-grown and isolated without iodized sea salt, making it safe for acne-prone skin. The gentle exfoliating action from fruit acids derived from sugarcane, lemon, orange, and apple also helps improve cell turnover without clogging pores, which can benefit acne-prone skin looking to address both breakouts and early signs of aging at the same time.

Most users notice improved radiance and hydration within the first few weeks of consistent use. Visible improvements in firmness, elasticity, and tone correction typically become more apparent after 6 to 8 weeks, as the formula works to support collagen synthesis and cellular repair over time. Results build with daily use, so consistency is key.

For best results, use iS Clinical GeneXC Serum both morning and evening. The antioxidant protection from ascorbic acid, green tea extract, and arginine ferulate is especially valuable during the day when your skin faces environmental stressors and UV exposure. Overnight, the regenerative ingredients, including the Extremozymes and collagen-supporting amino acids, can work alongside your skin's natural repair cycle. Always follow with a broad-spectrum SPF in the morning.

iS Clinical GeneXC Serum is formulated at a pH of approximately 3.0, which allows the ascorbic acid to remain effective but may cause mild tingling on first use, particularly on sensitive or reactive skin. If you have easily reactive skin, start by applying every other evening and gradually increase to daily use as your skin adjusts. Pairing it with a soothing, hydrating serum can also help ease the transition.

Yes, iS Clinical GeneXC Serum layers well with most actives. If you are using a retinol, apply GeneXC Serum first and allow it to fully absorb before applying your retinol product. The antioxidants, Extremozymes, and amino acids in this formula can actually complement retinol by supporting skin barrier integrity and helping to offset potential irritation from stronger exfoliating actives.

Refrigeration is not required, but storing iS Clinical GeneXC Serum in a cool, dark location will help preserve the potency of the ascorbic acid and other active ingredients. Keep the cap tightly closed between uses and avoid prolonged exposure to direct sunlight or heat, both of which can accelerate oxidation and reduce the effectiveness of vitamin C over time.

Art of Skin Care is an authorized retailer of iS Clinical, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if iS Clinical GeneXC Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.