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GlyMed Plus Retinol Rejuvenation Serum is a corrective gel serum formulated with a maximum concentration of 5% retinol to visibly reduce fine lines, wrinkles, uneven pigmentation, and breakouts over time. The retinol is micro-encapsulated, meaning it penetrates quickly and releases gradually into the skin, which helps minimize the dryness and irritation that often comes with high-strength retinol formulas. It carries a light herbal scent from rosemary leaf oil and geranium oil.
Key Benefits
Speeds Up Cell Turnover A 5% concentration of micro-encapsulated retinol accelerates the rate at which your skin sheds and renews itself, which gradually fades pigmentation, smooths rough texture, and reduces the frequency of breakouts.
Stimulates Collagen Production Retinol signals the skin to produce more collagen, which means fine lines and wrinkles become less defined with consistent use over time.
Firms and Strengthens Skin Two peptides, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine and palmitoyl dipeptide-5 diaminohydroxybutyrate, work alongside retinol to support the skin's structural proteins, improving firmness and resilience.
Draws In and Holds Moisture Hyaluronic acid pulls water into the skin and helps retain it, so the serum delivers active correction without leaving skin feeling tight or stripped.
Delivers Antioxidant Support Tocopheryl acetate (vitamin E) and acne-safe refined olive oil help neutralize environmental damage while supporting the skin barrier throughout the renewal process.
If you are ready to address fine lines, wrinkles, uneven skin tone, or recurring breakouts with a high-strength retinol, this serum is built for that goal. It is best suited for skin that has some previous experience with retinol and is ready to step up to a maximum-concentration formula.
Ideal for normal, oily, combination, or acne-prone skin types looking for visible correction over time. The micro-encapsulated delivery makes the high retinol concentration more tolerable than traditional formulas, but this is still a potent serum that requires a gradual introduction.
This serum is not recommended for very sensitive, reactive, rosacea-prone, or eczema-prone skin without guidance from a skincare professional.
Start with every 2 to 3 nights for the first two weeks, then build toward nightly use only once your skin has adjusted without significant dryness or flaking. If irritation does appear, scale back frequency rather than stopping entirely, consistency at a lower cadence still delivers results.
Cleanse and tone your skin before applying.
Apply 1 pump to the face, neck, and chest in the evening.
Layer a moisturizer on top to support the skin barrier.
Frequency: Begin by applying every 2 to 3 days for the first 1 to 2 weeks, then gradually increase to nightly use as tolerated. Some initial redness, dryness, or peeling is normal as your skin adjusts.
Morning routine: Always apply a broad-spectrum SPF the following morning and for at least one week after use, as retinol increases sun sensitivity.
Important: Avoid combining with other exfoliants or acids, including AHAs, BHAs, and vitamin C, unless directed by a skincare professional.
Aqua (Water), Cetearyl Ethylhexanoate, Caprylic/Capric Triglyceride, Hyaluronic Acid, Retinol (Vitamin A), Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, *Olea Europaea (Olive) Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Tocopheryl Acetate (Vitamin E Acetate), Retinyl Palmitate (Vitamin A Ester), Glycerin, Sucrose Tristearate, Bis-Diglyceryl Polyacyladipate -2, Polysorbate 60, PEG-20, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Rosmarinus Officinalis (Rosemary) Leaf Oil, Pelargonium Graveolens (Geranium) Oil, Phenoxyethanol, Ethylhexylglycerin, Triethanolamine *Refined to be acne safe
How does the micro-encapsulated retinol in GlyMed Plus Retinol Rejuvenation Serum reduce irritation?
Micro-encapsulation wraps the retinol in a protective coating that allows it to absorb into the skin quickly and then release slowly over time. This controlled delivery means less immediate exposure to the surface of the skin, which significantly reduces the dryness, redness, and peeling that high-concentration retinol formulas often cause. It is what makes a 5% retinol serum approachable for more skin types.
What skin concerns does GlyMed Plus Retinol Rejuvenation Serum address?
This serum targets fine lines, wrinkles, uneven skin tone, hyperpigmentation, rough texture, and acne. The 5% retinol drives accelerated cell turnover, which gradually resurfaces the skin and fades discoloration, while also stimulating collagen production to soften the appearance of lines and wrinkles over time.
What peptides are in GlyMed Plus Retinol Rejuvenation Serum and what do they do?
The serum contains palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine and palmitoyl dipeptide-5 diaminohydroxybutyrate, two peptides known for supporting the skin's structural proteins. They work alongside retinol to improve firmness and skin resilience, making this more than a single-active formula.
Is GlyMed Plus Retinol Rejuvenation Serum appropriate for acne-prone skin?
Yes, retinol is one of the most well-supported ingredients for reducing breakouts because it keeps pores clear by accelerating cell turnover. The olive oil in this formula has also been refined to be acne-safe, so it delivers emollient support without contributing to congestion. If you are actively breaking out and new to retinol, starting with a lower frequency is a smart approach.
Can GlyMed Plus Retinol Rejuvenation Serum be used with other active ingredients?
It is best not to layer this serum with other exfoliants or acids, including AHAs, BHAs, and vitamin C, on the same night. These combinations can push retinol's irritation potential higher than most skin tolerates. If you use other actives in your routine, a skincare professional can help you stagger them in a way that works for your skin. You can reach out to our team through a free skincare consultation for personalized guidance.
How long does it take to see results from GlyMed Plus Retinol Rejuvenation Serum?
Most people begin to notice smoother texture and a reduction in breakouts within four to six weeks of consistent use. Visible improvement in fine lines, wrinkles, and pigmentation typically takes eight to twelve weeks, as those changes rely on collagen remodeling and completed skin cycles. Consistency is what drives results with retinol.
Does GlyMed Plus Retinol Rejuvenation Serum contain fragrance?
The serum contains rosemary leaf oil and geranium oil, which contribute a light herbal scent. These are naturally derived botanical oils rather than synthetic fragrance compounds. If your skin is highly reactive or fragrance-sensitive, this is worth noting before use.
Why buy GlyMed Plus Retinol Rejuvenation Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of GlyMed Plus, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if GlyMed Plus Retinol Rejuvenation Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
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GlyMed Plus Retinol Rejuvenation Serum is a corrective gel serum formulated with a maximum concentration of 5% retinol to visibly reduce fine lines, wrinkles, uneven pigmentation, and breakouts over time. The retinol is micro-encapsulated, meaning it penetrates quickly and releases gradually into the skin, which helps minimize the dryness and irritation that often comes with high-strength retinol formulas. It carries a light herbal scent from rosemary leaf oil and geranium oil.
Key Benefits
Speeds Up Cell Turnover A 5% concentration of micro-encapsulated retinol accelerates the rate at which your skin sheds and renews itself, which gradually fades pigmentation, smooths rough texture, and reduces the frequency of breakouts.
Stimulates Collagen Production Retinol signals the skin to produce more collagen, which means fine lines and wrinkles become less defined with consistent use over time.
Firms and Strengthens Skin Two peptides, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine and palmitoyl dipeptide-5 diaminohydroxybutyrate, work alongside retinol to support the skin's structural proteins, improving firmness and resilience.
Draws In and Holds Moisture Hyaluronic acid pulls water into the skin and helps retain it, so the serum delivers active correction without leaving skin feeling tight or stripped.
Delivers Antioxidant Support Tocopheryl acetate (vitamin E) and acne-safe refined olive oil help neutralize environmental damage while supporting the skin barrier throughout the renewal process.
If you are ready to address fine lines, wrinkles, uneven skin tone, or recurring breakouts with a high-strength retinol, this serum is built for that goal. It is best suited for skin that has some previous experience with retinol and is ready to step up to a maximum-concentration formula.
Ideal for normal, oily, combination, or acne-prone skin types looking for visible correction over time. The micro-encapsulated delivery makes the high retinol concentration more tolerable than traditional formulas, but this is still a potent serum that requires a gradual introduction.
This serum is not recommended for very sensitive, reactive, rosacea-prone, or eczema-prone skin without guidance from a skincare professional.
Start with every 2 to 3 nights for the first two weeks, then build toward nightly use only once your skin has adjusted without significant dryness or flaking. If irritation does appear, scale back frequency rather than stopping entirely, consistency at a lower cadence still delivers results.
Cleanse and tone your skin before applying.
Apply 1 pump to the face, neck, and chest in the evening.
Layer a moisturizer on top to support the skin barrier.
Frequency: Begin by applying every 2 to 3 days for the first 1 to 2 weeks, then gradually increase to nightly use as tolerated. Some initial redness, dryness, or peeling is normal as your skin adjusts.
Morning routine: Always apply a broad-spectrum SPF the following morning and for at least one week after use, as retinol increases sun sensitivity.
Important: Avoid combining with other exfoliants or acids, including AHAs, BHAs, and vitamin C, unless directed by a skincare professional.
Aqua (Water), Cetearyl Ethylhexanoate, Caprylic/Capric Triglyceride, Hyaluronic Acid, Retinol (Vitamin A), Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, *Olea Europaea (Olive) Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Tocopheryl Acetate (Vitamin E Acetate), Retinyl Palmitate (Vitamin A Ester), Glycerin, Sucrose Tristearate, Bis-Diglyceryl Polyacyladipate -2, Polysorbate 60, PEG-20, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Rosmarinus Officinalis (Rosemary) Leaf Oil, Pelargonium Graveolens (Geranium) Oil, Phenoxyethanol, Ethylhexylglycerin, Triethanolamine *Refined to be acne safe
How does the micro-encapsulated retinol in GlyMed Plus Retinol Rejuvenation Serum reduce irritation?
Micro-encapsulation wraps the retinol in a protective coating that allows it to absorb into the skin quickly and then release slowly over time. This controlled delivery means less immediate exposure to the surface of the skin, which significantly reduces the dryness, redness, and peeling that high-concentration retinol formulas often cause. It is what makes a 5% retinol serum approachable for more skin types.
What skin concerns does GlyMed Plus Retinol Rejuvenation Serum address?
This serum targets fine lines, wrinkles, uneven skin tone, hyperpigmentation, rough texture, and acne. The 5% retinol drives accelerated cell turnover, which gradually resurfaces the skin and fades discoloration, while also stimulating collagen production to soften the appearance of lines and wrinkles over time.
What peptides are in GlyMed Plus Retinol Rejuvenation Serum and what do they do?
The serum contains palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine and palmitoyl dipeptide-5 diaminohydroxybutyrate, two peptides known for supporting the skin's structural proteins. They work alongside retinol to improve firmness and skin resilience, making this more than a single-active formula.
Is GlyMed Plus Retinol Rejuvenation Serum appropriate for acne-prone skin?
Yes, retinol is one of the most well-supported ingredients for reducing breakouts because it keeps pores clear by accelerating cell turnover. The olive oil in this formula has also been refined to be acne-safe, so it delivers emollient support without contributing to congestion. If you are actively breaking out and new to retinol, starting with a lower frequency is a smart approach.
Can GlyMed Plus Retinol Rejuvenation Serum be used with other active ingredients?
It is best not to layer this serum with other exfoliants or acids, including AHAs, BHAs, and vitamin C, on the same night. These combinations can push retinol's irritation potential higher than most skin tolerates. If you use other actives in your routine, a skincare professional can help you stagger them in a way that works for your skin. You can reach out to our team through a free skincare consultation for personalized guidance.
How long does it take to see results from GlyMed Plus Retinol Rejuvenation Serum?
Most people begin to notice smoother texture and a reduction in breakouts within four to six weeks of consistent use. Visible improvement in fine lines, wrinkles, and pigmentation typically takes eight to twelve weeks, as those changes rely on collagen remodeling and completed skin cycles. Consistency is what drives results with retinol.
Does GlyMed Plus Retinol Rejuvenation Serum contain fragrance?
The serum contains rosemary leaf oil and geranium oil, which contribute a light herbal scent. These are naturally derived botanical oils rather than synthetic fragrance compounds. If your skin is highly reactive or fragrance-sensitive, this is worth noting before use.
Why buy GlyMed Plus Retinol Rejuvenation Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of GlyMed Plus, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if GlyMed Plus Retinol Rejuvenation Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
I am still in the "introductory" phase of using this product. Began with every 3 days, then every other day. So far, it is only a tiny bit stingly, so I will move up to using every night this week. I cannot speak to the results yet, but I trust it is doing the job!!!
Glymed Plus Retinol Rejuvenation Serum
Serum feels very silky and has a wonderful scent.
Delayed perfection
I feel the product is probably wonderful, but still trying to figure out how to use