iS Clinical Hydra-Cool Serum
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The iS Clinical Hydra-Cool Serum is a lightweight, fast-absorbing serum designed to deliver immediate hydration, visible calming of redness, and long-term moisture barrier repair for sensitive, reactive, or post-procedure skin. It features a noticeable cooling sensation from menthol that provides instant relief on contact, making it one of the few hydrating serums that addresses both acute skin discomfort and the underlying causes of barrier compromise. The formula is fragrance-free aside from the functional menthol and free of parabens.
Key Benefits
Immediate, deep hydration Sodium hyaluronate draws moisture into the skin and binds up to 1,000 times its weight in water, quickly relieving tightness and dehydration while plumping the look of the skin.
Moisture barrier reinforcement Polyporus umbellatus (mushroom) extract works alongside pantothenic acid (vitamin B5) to strengthen the skin's natural barrier, reduce transepidermal water loss, and protect against the environmental stressors that trigger sensitivity.
Visible reduction in redness and inflammation Three bioactive compounds derived from centella asiatica, asiaticoside, asiatic acid, and madecassic acid, work together to calm active inflammation, reduce redness, and support the skin's natural healing process.
Instant cooling relief Menthol provides a cooling effect the moment the serum touches skin, soothing reactive, overheated, or sun-exposed skin and easing visible discomfort without causing irritation at its formulated concentration.
Accelerated skin recovery Pantothenic acid (vitamin B5) supports cellular repair and healing, making this serum especially effective after chemical peels, microneedling, laser treatments, or any procedure that leaves skin sensitized.
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If your skin tends to run reactive, feels tight or uncomfortable after cleansing, or flushes easily in response to temperature, products, or stress, this serum was built for how your skin behaves. It is particularly well-suited for those managing rosacea, chronic redness, or a compromised moisture barrier that keeps skin stuck in a cycle of irritation.
This serum is also an excellent fit for anyone in a post-procedure recovery phase. After chemical peels, microneedling, laser resurfacing, or extractions, skin needs hydration and anti-inflammatory support simultaneously, and this formula provides both without overwhelming sensitized skin.
Despite its calming focus, the lightweight texture makes it a strong choice for combination and oily skin types who want moisture without weight. It absorbs cleanly, layers well under other products, and does not contribute to congestion.
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Store this serum in the refrigerator. The cooling effect from the menthol is already noticeable at room temperature, but a chilled application takes it noticeably further and is especially comforting after sun exposure, professional treatments, or any time skin feels hot and reactive.
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Prepare: Cleanse and tone skin, then apply to a clean, slightly damp face.
Apply: Dispense a pea-sized amount and smooth evenly over the face, neck, and chest.
Frequency: Use morning and evening. Layer with your preferred moisturizer and follow with broad-spectrum SPF during daytime use.
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Key Ingredients
- Sodium Hyaluronate: The purest, salt form of hyaluronic acid, a master humectant that holds up to 1,000 times its weight in water to provide maximum hydration and plumping benefits to thirsty skin.
- Vitamin B5 (Pantothenic Acid): Demonstrates significant potential to reduce hormonal acne and control oil production. Also shown to help the oxidation process, supporting healthy digestion that can also reduce inflammation and increase nutrient absorption.
- Centella Asiatica Extract: Helps to strengthen and repair the skin's moisture barrier with potent anti-inflammatory benefits and antioxidant protection.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Sodium Hyaluronate, Pantothenic Acid, Pentylene Glycol, Menthol, Phenoxyethanol, Asiaticoside, Polyporus Umbellatus (Mushroom) Extract, Asiatic Acid, Madecassic Acid, Blue 1 (CI 42090).
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Will the menthol in iS Clinical Hydra-Cool Serum irritate sensitive skin?
The menthol in iS Clinical Hydra-Cool Serum is included at a concentration calibrated to deliver a cooling sensation without triggering irritation for most sensitive skin types. The centella asiatica bioactives (asiaticoside, asiatic acid, and madecassic acid) alongside pantothenic acid actively work to calm inflammation, which offsets any potential reactivity. If your skin is extremely reactive, a patch test on a small area before full application is a good first step.
Can I use iS Clinical Hydra-Cool Serum immediately after professional treatments like chemical peels or microneedling?
Yes, iS Clinical Hydra-Cool Serum is one of the most appropriate serums to reach for in a post-procedure setting. The menthol cools and soothes on contact, sodium hyaluronate restores hydration to compromised skin, and the centella asiatica bioactives help reduce redness and support tissue repair. Many estheticians recommend it specifically for the days following peels, microneedling, laser treatments, or extractions.
How is iS Clinical Hydra-Cool Serum different from a standard hyaluronic acid serum?
Where a standard hyaluronic acid serum focuses primarily on surface hydration, iS Clinical Hydra-Cool Serum layers in multiple additional functions. Sodium hyaluronate handles moisture delivery, while polyporus umbellatus mushroom extract and pantothenic acid reinforce the barrier to keep that moisture in. The centella asiatica bioactives (asiaticoside, asiatic acid, and madecassic acid) reduce active inflammation, and the menthol provides immediate cooling relief that no basic hyaluronic serum offers. It is a multi-action formula, not a single-ingredient hydrator.
Is iS Clinical Hydra-Cool Serum appropriate for rosacea-prone skin?
iS Clinical Hydra-Cool Serum is well-suited for rosacea-prone skin. The three centella asiatica bioactives work to reduce the visible redness and inflammatory response that characterize rosacea, while polyporus umbellatus mushroom extract and pantothenic acid help rebuild the barrier integrity that is often weakened in rosacea. The cooling sensation from the menthol can also provide noticeable comfort during flare-ups. Introduce it gradually if your skin is currently in an active flare.
What does iS Clinical Hydra-Cool Serum feel like when applied?
The texture is lightweight and water-like, and it absorbs quickly without leaving any sticky or heavy residue. Within seconds of application, you will notice a distinct cooling sensation from the menthol that feels refreshing rather than intense. It layers cleanly under moisturizer and does not pill or interfere with other products in your routine.
Is iS Clinical Hydra-Cool Serum safe for oily or acne-prone skin?
Yes, the serum's lightweight, fast-absorbing formula makes it suitable for oily and acne-prone skin types that still need hydration. It delivers moisture without heaviness and does not contain occlusive or pore-clogging ingredients. The anti-inflammatory properties of the centella asiatica bioactives and pantothenic acid can also be beneficial for skin that experiences redness or irritation alongside breakouts.
How should iS Clinical Hydra-Cool Serum be layered in a skincare routine?
Apply iS Clinical Hydra-Cool Serum after cleansing and any toning steps, while skin is still slightly damp. As a water-based serum, it should go on before thicker creams or oils. Follow with your preferred moisturizer to seal in the hydration, and in the morning, always finish with a broad-spectrum SPF. It pairs well with calming or barrier-repair moisturizers for added benefit.
Why buy iS Clinical Hydra-Cool Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of iS Clinical, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if iS Clinical Hydra-Cool Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
The iS Clinical Hydra-Cool Serum is a lightweight, fast-absorbing serum designed to deliver immediate hydration, visible calming of redness, and long-term moisture barrier repair for sensitive, reactive, or post-procedure skin. It features a noticeable cooling sensation from menthol that provides instant relief on contact, making it one of the few hydrating serums that addresses both acute skin discomfort and the underlying causes of barrier compromise. The formula is fragrance-free aside from the functional menthol and free of parabens.
Key Benefits
Immediate, deep hydration Sodium hyaluronate draws moisture into the skin and binds up to 1,000 times its weight in water, quickly relieving tightness and dehydration while plumping the look of the skin.
Moisture barrier reinforcement Polyporus umbellatus (mushroom) extract works alongside pantothenic acid (vitamin B5) to strengthen the skin's natural barrier, reduce transepidermal water loss, and protect against the environmental stressors that trigger sensitivity.
Visible reduction in redness and inflammation Three bioactive compounds derived from centella asiatica, asiaticoside, asiatic acid, and madecassic acid, work together to calm active inflammation, reduce redness, and support the skin's natural healing process.
Instant cooling relief Menthol provides a cooling effect the moment the serum touches skin, soothing reactive, overheated, or sun-exposed skin and easing visible discomfort without causing irritation at its formulated concentration.
Accelerated skin recovery Pantothenic acid (vitamin B5) supports cellular repair and healing, making this serum especially effective after chemical peels, microneedling, laser treatments, or any procedure that leaves skin sensitized.
If your skin tends to run reactive, feels tight or uncomfortable after cleansing, or flushes easily in response to temperature, products, or stress, this serum was built for how your skin behaves. It is particularly well-suited for those managing rosacea, chronic redness, or a compromised moisture barrier that keeps skin stuck in a cycle of irritation.
This serum is also an excellent fit for anyone in a post-procedure recovery phase. After chemical peels, microneedling, laser resurfacing, or extractions, skin needs hydration and anti-inflammatory support simultaneously, and this formula provides both without overwhelming sensitized skin.
Despite its calming focus, the lightweight texture makes it a strong choice for combination and oily skin types who want moisture without weight. It absorbs cleanly, layers well under other products, and does not contribute to congestion.
Store this serum in the refrigerator. The cooling effect from the menthol is already noticeable at room temperature, but a chilled application takes it noticeably further and is especially comforting after sun exposure, professional treatments, or any time skin feels hot and reactive.
Prepare: Cleanse and tone skin, then apply to a clean, slightly damp face.
Apply: Dispense a pea-sized amount and smooth evenly over the face, neck, and chest.
Frequency: Use morning and evening. Layer with your preferred moisturizer and follow with broad-spectrum SPF during daytime use.
- Sodium Hyaluronate: The purest, salt form of hyaluronic acid, a master humectant that holds up to 1,000 times its weight in water to provide maximum hydration and plumping benefits to thirsty skin.
- Vitamin B5 (Pantothenic Acid): Demonstrates significant potential to reduce hormonal acne and control oil production. Also shown to help the oxidation process, supporting healthy digestion that can also reduce inflammation and increase nutrient absorption.
- Centella Asiatica Extract: Helps to strengthen and repair the skin's moisture barrier with potent anti-inflammatory benefits and antioxidant protection.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Sodium Hyaluronate, Pantothenic Acid, Pentylene Glycol, Menthol, Phenoxyethanol, Asiaticoside, Polyporus Umbellatus (Mushroom) Extract, Asiatic Acid, Madecassic Acid, Blue 1 (CI 42090).
Will the menthol in iS Clinical Hydra-Cool Serum irritate sensitive skin?
The menthol in iS Clinical Hydra-Cool Serum is included at a concentration calibrated to deliver a cooling sensation without triggering irritation for most sensitive skin types. The centella asiatica bioactives (asiaticoside, asiatic acid, and madecassic acid) alongside pantothenic acid actively work to calm inflammation, which offsets any potential reactivity. If your skin is extremely reactive, a patch test on a small area before full application is a good first step.
Can I use iS Clinical Hydra-Cool Serum immediately after professional treatments like chemical peels or microneedling?
Yes, iS Clinical Hydra-Cool Serum is one of the most appropriate serums to reach for in a post-procedure setting. The menthol cools and soothes on contact, sodium hyaluronate restores hydration to compromised skin, and the centella asiatica bioactives help reduce redness and support tissue repair. Many estheticians recommend it specifically for the days following peels, microneedling, laser treatments, or extractions.
How is iS Clinical Hydra-Cool Serum different from a standard hyaluronic acid serum?
Where a standard hyaluronic acid serum focuses primarily on surface hydration, iS Clinical Hydra-Cool Serum layers in multiple additional functions. Sodium hyaluronate handles moisture delivery, while polyporus umbellatus mushroom extract and pantothenic acid reinforce the barrier to keep that moisture in. The centella asiatica bioactives (asiaticoside, asiatic acid, and madecassic acid) reduce active inflammation, and the menthol provides immediate cooling relief that no basic hyaluronic serum offers. It is a multi-action formula, not a single-ingredient hydrator.
Is iS Clinical Hydra-Cool Serum appropriate for rosacea-prone skin?
iS Clinical Hydra-Cool Serum is well-suited for rosacea-prone skin. The three centella asiatica bioactives work to reduce the visible redness and inflammatory response that characterize rosacea, while polyporus umbellatus mushroom extract and pantothenic acid help rebuild the barrier integrity that is often weakened in rosacea. The cooling sensation from the menthol can also provide noticeable comfort during flare-ups. Introduce it gradually if your skin is currently in an active flare.
What does iS Clinical Hydra-Cool Serum feel like when applied?
The texture is lightweight and water-like, and it absorbs quickly without leaving any sticky or heavy residue. Within seconds of application, you will notice a distinct cooling sensation from the menthol that feels refreshing rather than intense. It layers cleanly under moisturizer and does not pill or interfere with other products in your routine.
Is iS Clinical Hydra-Cool Serum safe for oily or acne-prone skin?
Yes, the serum's lightweight, fast-absorbing formula makes it suitable for oily and acne-prone skin types that still need hydration. It delivers moisture without heaviness and does not contain occlusive or pore-clogging ingredients. The anti-inflammatory properties of the centella asiatica bioactives and pantothenic acid can also be beneficial for skin that experiences redness or irritation alongside breakouts.
How should iS Clinical Hydra-Cool Serum be layered in a skincare routine?
Apply iS Clinical Hydra-Cool Serum after cleansing and any toning steps, while skin is still slightly damp. As a water-based serum, it should go on before thicker creams or oils. Follow with your preferred moisturizer to seal in the hydration, and in the morning, always finish with a broad-spectrum SPF. It pairs well with calming or barrier-repair moisturizers for added benefit.
Why buy iS Clinical Hydra-Cool Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of iS Clinical, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if iS Clinical Hydra-Cool Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
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iS Clinical Hydra-Cool Serum
- GTGinger T.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 30-39What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Blemish-prone, OilinessRated 4 out of 5 stars12 months agoGreat, lightweight hydrating serum
I love the cooling effect of this serum and how it helps with redness/irritation. I pair it with a hydrating spray and find that to be the perfect combination for me
Was this helpful? - MMelissaReviewingiS Clinical Hydra-Cool SerumI recommend this productRated 5 out of 5 stars1 year ago5 Stars
Great product
Was this helpful? - JJJessica J.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 18-29What are your skin concerns? Blemish-proneRated 5 out of 5 stars2 years agoiS Clinical Hydra-Cool Serum
LOVE
I LOVE this product! One of my absolute favorite staple products for hydration!
Was this helpful? - SPShaila P.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 18-29What are your skin concerns? Blemish-proneRated 5 out of 5 stars2 years agoiS Clinical Hydra-Cool Serum
Best Product for my Acne Prone Skin
I absolutely love the cooling minty feeling this product gives my skin. It provides excellent hydration in addition to my daily moisturizer. When I don't use it, my skin dries out quickly but this product helps maintain that extra layer of moisture that my skin needs to thrive.
Was this helpful? - KBKasey B.Verified BuyerReviewingiS Clinical Hydra-Cool SerumI recommend this productHow old are you? 40-49Rated 5 out of 5 stars3 years agoiS Clinical Hydra-Cool Serum
My teenager loves this product!
My teenager loves this product! She says she likes it bc it has a fast drying time.
Was this helpful?