FREE U.S. SHIPPING ON ORDERS $49+

iS Clinical Pro-Heal Serum Advance+

iS Clinical Pro-Heal Serum Advance+ is a targeted antioxidant serum from iS Clinical that calms reactive skin, reduces visible redness, and rebuilds a compromised barrier without relying on harsh actives. It carries a mild herbal scent from the olive leaf and mushroom extracts that fades quickly after application.

Key Benefits

Reduces visible redness and soothes reactive skin Ascorbic acid and olive leaf extract work together to quiet inflammation, making this especially effective for rosacea-prone or chronically sensitized skin.

Rebuilds a weakened skin barrier Polyporus umbellatus mushroom extract reinforces the skin's protective layer while improving its ability to retain moisture, so skin becomes more resilient with continued use.

Delivers broad-spectrum antioxidant protection Tocopherol and ascorbic acid work synergistically to neutralize free radicals before they can trigger sensitivity or accelerate visible signs of aging.

Fades post-inflammatory discoloration without irritation Arbutin gently targets uneven tone caused by past breakouts or inflammation, and the formula's low pH of 3.1 optimizes absorption while keeping tolerance high.

Supports cellular health through antioxidant-form retinol The retinol in this formula functions as a protective antioxidant, not an exfoliant, preserving cellular integrity without causing the peeling or sensitivity associated with traditional retinoids.

iS Clinical Pro-Heal Serum Advance+

Antioxidant serum with vitamin C that calms redness, restores barrier function, and soothes sensitive or rosacea-prone skin daily.
4.8
Rated 4.8 out of 5 stars
17 Reviews
Regular price $104.00
Unit price
per 
Earn points for this product!
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Compromised Barrier
  • Redness/Rosacea
  • Inflammation
Lotion bottle icons

Best For:

  • Combination
  • Dry
  • Normal
  • Oily
  • Sensitive

iS Clinical Pro-Heal Serum Advance+

iS Clinical Pro-Heal Serum Advance+ is a targeted antioxidant serum from iS Clinical that calms reactive skin, reduces visible redness, and rebuilds a compromised barrier without relying on harsh actives. It carries a mild herbal scent from the olive leaf and mushroom extracts that fades quickly after application.

Key Benefits

Reduces visible redness and soothes reactive skin Ascorbic acid and olive leaf extract work together to quiet inflammation, making this especially effective for rosacea-prone or chronically sensitized skin.

Rebuilds a weakened skin barrier Polyporus umbellatus mushroom extract reinforces the skin's protective layer while improving its ability to retain moisture, so skin becomes more resilient with continued use.

Delivers broad-spectrum antioxidant protection Tocopherol and ascorbic acid work synergistically to neutralize free radicals before they can trigger sensitivity or accelerate visible signs of aging.

Fades post-inflammatory discoloration without irritation Arbutin gently targets uneven tone caused by past breakouts or inflammation, and the formula's low pH of 3.1 optimizes absorption while keeping tolerance high.

Supports cellular health through antioxidant-form retinol The retinol in this formula functions as a protective antioxidant, not an exfoliant, preserving cellular integrity without causing the peeling or sensitivity associated with traditional retinoids.

iS Clinical Pro-Heal Serum Advance+

4.8
Rated 4.8 out of 5 stars
Based on 17 reviews
Total 5 star reviews: 14 Total 4 star reviews: 2 Total 3 star reviews: 1 Total 2 star reviews: 0 Total 1 star reviews: 0
17 reviews
  • JA
    Julie A. C.
    Verified Buyer
    Reviewing
    iS Clinical Pro-Heal Serum Advance+
    I recommend this product
    How old are you? 40-49
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Pigmentation, Blemish-prone
    Rated 5 out of 5 stars
    2 days ago
    Fabulous for acne prone skin

    I had been using is clinical serums for a few years when last fall, I was influenced to try another hyped skin care line. The other line gave me horrible acne. Something I was not expecting to be dealing with at 46! Especially because the other line swore it would not affect my skin that way! But I had horrible clogged pores on my chin and forehead -- something I've never had before. I switched back to IS clinical, and my skin cleared up immediately. This serum is fantastic for anti-aging, as well as fighting acne.

  • MM
    Madeline M.
    Verified Buyer
    Reviewing
    iS Clinical Pro-Heal Serum Advance+
    I recommend this product
    How old are you? 30-39
    What is your skin type? Normal
    What is your skin tone? Fair
    What are your skin concerns? Sensitivity, Redness, Dryness, Pigmentation, Wrinkles
    Rated 5 out of 5 stars
    5 months ago
    3rd repurchase

    This is my third repurchase. This is the best vit c serum. And it has the added benefit of helping me clear break outs quickly.

  • LB
    Lisa B.
    Verified Buyer
    Reviewing
    iS Clinical Pro-Heal Serum Advance+
    I recommend this product
    How old are you? 40-49
    What is your skin type? Dry
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Sensitivity, Wrinkles
    Rated 5 out of 5 stars
    5 months ago
    Pretty good

    I read reviews that this was more gentle than other vitamin C brands, so I thought I would try it as I have sensitive skin. I use sparingly because it seems strong. I don’t notice a difference, but do like being able to use a Vitamin C without a reaction

  • LF
    Lisa F.
    Verified Buyer
    Reviewing
    iS Clinical Pro-Heal Serum Advance+
    I recommend this product
    How old are you? 40-49
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Acne, Ageing, Redness, Sensitivity, Wrinkles
    Rated 5 out of 5 stars
    10 months ago
    Best Vitamin C Product!

    Amazing product! My skin is so much better after using it. Love this product.

  • VC
    Vivian C.
    Verified Buyer
    Reviewing
    iS Clinical Pro-Heal Serum Advance+
    I recommend this product
    How old are you? 30-39
    What is your skin type? Combination
    What is your skin tone? Tan
    What are your skin concerns? Redness, Acne, Ageing, Pigmentation, Sun Damage
    Rated 4 out of 5 stars
    1 year ago
    Vit c obsessed

    I love the “non” smell vitamin c has. It makes my skin so bright and the pores smaller.