iS Clinical Pro-Heal Serum Advance+
iS Clinical Pro-Heal Serum Advance+ is a targeted antioxidant serum from iS Clinical that calms reactive skin, reduces visible redness, and rebuilds a compromised barrier without relying on harsh actives. It carries a mild herbal scent from the olive leaf and mushroom extracts that fades quickly after application.
Key Benefits
Reduces visible redness and soothes reactive skin Ascorbic acid and olive leaf extract work together to quiet inflammation, making this especially effective for rosacea-prone or chronically sensitized skin.
Rebuilds a weakened skin barrier Polyporus umbellatus mushroom extract reinforces the skin's protective layer while improving its ability to retain moisture, so skin becomes more resilient with continued use.
Delivers broad-spectrum antioxidant protection Tocopherol and ascorbic acid work synergistically to neutralize free radicals before they can trigger sensitivity or accelerate visible signs of aging.
Fades post-inflammatory discoloration without irritation Arbutin gently targets uneven tone caused by past breakouts or inflammation, and the formula's low pH of 3.1 optimizes absorption while keeping tolerance high.
Supports cellular health through antioxidant-form retinol The retinol in this formula functions as a protective antioxidant, not an exfoliant, preserving cellular integrity without causing the peeling or sensitivity associated with traditional retinoids.
If your skin flares easily, stays persistently red, or has become sensitized from over-exfoliation, environmental exposure, or chronic inflammation, this serum addresses those concerns without adding more stress to your skin. It is particularly well-suited for rosacea-prone skin, barrier-compromised skin, and anyone in recovery following a chemical peel, microneedling, or laser treatment.
Mature skin that has grown more reactive over time will also benefit from the combination of antioxidant protection and barrier support this serum provides. If you have avoided vitamin C serums in the past because they caused stinging or redness, the calming botanicals here make ascorbic acid genuinely tolerable, even for highly sensitive skin types.
The retinol in this formula is doing something different than what most people expect. It functions as an antioxidant that protects cellular health rather than as an exfoliant that drives cell turnover, so you won't experience any flaking, purging, or adjustment period. This makes it safe to use daily, even during your skin's most reactive phases.
Prepare: After cleansing and toning, ensure skin is completely dry before applying.
Apply: Dispense 3-5 drops into your palm and press gently onto the face, neck, and chest.
Frequency: Use morning and evening. Follow with a moisturizer, and apply SPF every morning.
- Vitamin C (L-Ascorbic Acid): A powerful antioxidant with anti-inflammatory properties, which helps reduce skin redness, brighten complexion, and even skin tone.
- Vitamin E (Tocopherol): Soothes, brightens, and helps reverse and protect against environmental damage.
- Olive Leaf Extract: Nutrient-dense antioxidant that promotes wound healing and helps nourish and strengthen blemish-prone or compromised skin.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Ascorbic Acid, Laureth-4, Alcohol Denat., Pentylene Glycol, Propylene Glycol, Triethanolamine, Tocopherol, Glycerin, Bioflavonoids, Retinol, Olea Europaea (Olive) Leaf Extract, Zinc Sulfate, Polyporus Umbellatus (Mushroom) Extract, Arbutin, Polysorbate 20, Phenoxyethanol.
Can I use iS Clinical Pro-Heal Serum Advance+ if I have active rosacea?
Yes. iS Clinical Pro-Heal Serum Advance+ is formulated specifically to address the visible redness, inflammation, and sensitivity that characterize rosacea-prone skin. Ascorbic acid, olive leaf extract, and Polyporus umbellatus mushroom extract work together to calm reactivity and gradually strengthen your skin's ability to handle everyday stressors.
Will iS Clinical Pro-Heal Serum Advance+ cause purging or peeling?
No. The retinol in iS Clinical Pro-Heal Serum Advance+ acts as a cellular antioxidant rather than an exfoliant, so it does not trigger cell turnover or the purging phase associated with traditional retinoids. Sensitive or compromised skin can use this daily without any adjustment period.
How does iS Clinical Pro-Heal Serum Advance+ compare to other vitamin C serums?
Most high-strength vitamin C serums rely solely on ascorbic acid at a low pH, which can cause stinging or redness in reactive skin. iS Clinical Pro-Heal Serum Advance+ pairs ascorbic acid with olive leaf extract, mushroom extract, and bioflavonoids to deliver antioxidant benefits without triggering irritation. The low pH of 3.1 optimizes absorption while the calming botanicals help counteract any potential reactivity.
Can I layer iS Clinical Pro-Heal Serum Advance+ with other active ingredients?
Yes. Because iS Clinical Pro-Heal Serum Advance+ is formulated around sensitive and compromised skin, it layers well with most treatments. If you are using prescription retinoids or exfoliating acids, applying Pro-Heal Serum Advance+ first creates a protective, calming base that can improve your skin's tolerance for stronger actives.
How quickly will I see results with iS Clinical Pro-Heal Serum Advance+?
Many users notice a reduction in redness and irritation within the first few days of consistent use. More significant improvements in barrier strength, skin resilience, and uneven tone typically become visible within 4-6 weeks as the antioxidants accumulate and repair processes build on one another.
Does iS Clinical Pro-Heal Serum Advance+ have a fragrance or scent?
iS Clinical Pro-Heal Serum Advance+ has a mild herbal scent that comes naturally from the olive leaf and Polyporus umbellatus mushroom extracts in the formula. It is not artificially fragranced, and the scent dissipates quickly after application.
Can I use iS Clinical Pro-Heal Serum Advance+ after professional skin treatments?
Yes, and it is an excellent choice for post-procedure recovery. Following peels, microneedling, or laser treatments, skin is more vulnerable to inflammation and environmental stress. The antioxidants in iS Clinical Pro-Heal Serum Advance+ support the healing process while the calming botanicals reduce visible inflammation and help minimize downtime.
Why buy iS Clinical Pro-Heal Serum Advance+ from Art of Skin Care?
Art of Skin Care is an authorized retailer of iS Clinical, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if iS Clinical Pro-Heal Serum Advance+ is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
- Unit price
- /per
Primary Concerns:
- Compromised Barrier
- Redness/Rosacea
- Inflammation
Best For:
- Combination
- Dry
- Normal
- Oily
- Sensitive
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iS Clinical Pro-Heal Serum Advance+
iS Clinical Pro-Heal Serum Advance+ is a targeted antioxidant serum from iS Clinical that calms reactive skin, reduces visible redness, and rebuilds a compromised barrier without relying on harsh actives. It carries a mild herbal scent from the olive leaf and mushroom extracts that fades quickly after application.
Key Benefits
Reduces visible redness and soothes reactive skin Ascorbic acid and olive leaf extract work together to quiet inflammation, making this especially effective for rosacea-prone or chronically sensitized skin.
Rebuilds a weakened skin barrier Polyporus umbellatus mushroom extract reinforces the skin's protective layer while improving its ability to retain moisture, so skin becomes more resilient with continued use.
Delivers broad-spectrum antioxidant protection Tocopherol and ascorbic acid work synergistically to neutralize free radicals before they can trigger sensitivity or accelerate visible signs of aging.
Fades post-inflammatory discoloration without irritation Arbutin gently targets uneven tone caused by past breakouts or inflammation, and the formula's low pH of 3.1 optimizes absorption while keeping tolerance high.
Supports cellular health through antioxidant-form retinol The retinol in this formula functions as a protective antioxidant, not an exfoliant, preserving cellular integrity without causing the peeling or sensitivity associated with traditional retinoids.
If your skin flares easily, stays persistently red, or has become sensitized from over-exfoliation, environmental exposure, or chronic inflammation, this serum addresses those concerns without adding more stress to your skin. It is particularly well-suited for rosacea-prone skin, barrier-compromised skin, and anyone in recovery following a chemical peel, microneedling, or laser treatment.
Mature skin that has grown more reactive over time will also benefit from the combination of antioxidant protection and barrier support this serum provides. If you have avoided vitamin C serums in the past because they caused stinging or redness, the calming botanicals here make ascorbic acid genuinely tolerable, even for highly sensitive skin types.
The retinol in this formula is doing something different than what most people expect. It functions as an antioxidant that protects cellular health rather than as an exfoliant that drives cell turnover, so you won't experience any flaking, purging, or adjustment period. This makes it safe to use daily, even during your skin's most reactive phases.
Prepare: After cleansing and toning, ensure skin is completely dry before applying.
Apply: Dispense 3-5 drops into your palm and press gently onto the face, neck, and chest.
Frequency: Use morning and evening. Follow with a moisturizer, and apply SPF every morning.
- Vitamin C (L-Ascorbic Acid): A powerful antioxidant with anti-inflammatory properties, which helps reduce skin redness, brighten complexion, and even skin tone.
- Vitamin E (Tocopherol): Soothes, brightens, and helps reverse and protect against environmental damage.
- Olive Leaf Extract: Nutrient-dense antioxidant that promotes wound healing and helps nourish and strengthen blemish-prone or compromised skin.
- Mushroom Extract: Rich in fatty acids, improves the ability of the skin to retain moisture and maintain a healthy skin barrier, while boosting collagen and calming inflammation.
Water/Aqua/Eau, Ascorbic Acid, Laureth-4, Alcohol Denat., Pentylene Glycol, Propylene Glycol, Triethanolamine, Tocopherol, Glycerin, Bioflavonoids, Retinol, Olea Europaea (Olive) Leaf Extract, Zinc Sulfate, Polyporus Umbellatus (Mushroom) Extract, Arbutin, Polysorbate 20, Phenoxyethanol.
Can I use iS Clinical Pro-Heal Serum Advance+ if I have active rosacea?
Yes. iS Clinical Pro-Heal Serum Advance+ is formulated specifically to address the visible redness, inflammation, and sensitivity that characterize rosacea-prone skin. Ascorbic acid, olive leaf extract, and Polyporus umbellatus mushroom extract work together to calm reactivity and gradually strengthen your skin's ability to handle everyday stressors.
Will iS Clinical Pro-Heal Serum Advance+ cause purging or peeling?
No. The retinol in iS Clinical Pro-Heal Serum Advance+ acts as a cellular antioxidant rather than an exfoliant, so it does not trigger cell turnover or the purging phase associated with traditional retinoids. Sensitive or compromised skin can use this daily without any adjustment period.
How does iS Clinical Pro-Heal Serum Advance+ compare to other vitamin C serums?
Most high-strength vitamin C serums rely solely on ascorbic acid at a low pH, which can cause stinging or redness in reactive skin. iS Clinical Pro-Heal Serum Advance+ pairs ascorbic acid with olive leaf extract, mushroom extract, and bioflavonoids to deliver antioxidant benefits without triggering irritation. The low pH of 3.1 optimizes absorption while the calming botanicals help counteract any potential reactivity.
Can I layer iS Clinical Pro-Heal Serum Advance+ with other active ingredients?
Yes. Because iS Clinical Pro-Heal Serum Advance+ is formulated around sensitive and compromised skin, it layers well with most treatments. If you are using prescription retinoids or exfoliating acids, applying Pro-Heal Serum Advance+ first creates a protective, calming base that can improve your skin's tolerance for stronger actives.
How quickly will I see results with iS Clinical Pro-Heal Serum Advance+?
Many users notice a reduction in redness and irritation within the first few days of consistent use. More significant improvements in barrier strength, skin resilience, and uneven tone typically become visible within 4-6 weeks as the antioxidants accumulate and repair processes build on one another.
Does iS Clinical Pro-Heal Serum Advance+ have a fragrance or scent?
iS Clinical Pro-Heal Serum Advance+ has a mild herbal scent that comes naturally from the olive leaf and Polyporus umbellatus mushroom extracts in the formula. It is not artificially fragranced, and the scent dissipates quickly after application.
Can I use iS Clinical Pro-Heal Serum Advance+ after professional skin treatments?
Yes, and it is an excellent choice for post-procedure recovery. Following peels, microneedling, or laser treatments, skin is more vulnerable to inflammation and environmental stress. The antioxidants in iS Clinical Pro-Heal Serum Advance+ support the healing process while the calming botanicals reduce visible inflammation and help minimize downtime.
Why buy iS Clinical Pro-Heal Serum Advance+ from Art of Skin Care?
Art of Skin Care is an authorized retailer of iS Clinical, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if iS Clinical Pro-Heal Serum Advance+ is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
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iS Clinical Pro-Heal Serum Advance+
- JAJulie A. C.Verified BuyerReviewingiS Clinical Pro-Heal Serum Advance+I recommend this productHow old are you? 40-49What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Ageing, Pigmentation, Blemish-proneRated 5 out of 5 stars2 days agoFabulous for acne prone skin
I had been using is clinical serums for a few years when last fall, I was influenced to try another hyped skin care line. The other line gave me horrible acne. Something I was not expecting to be dealing with at 46! Especially because the other line swore it would not affect my skin that way! But I had horrible clogged pores on my chin and forehead -- something I've never had before. I switched back to IS clinical, and my skin cleared up immediately. This serum is fantastic for anti-aging, as well as fighting acne.
Was this helpful? - MMMadeline M.Verified BuyerReviewingiS Clinical Pro-Heal Serum Advance+I recommend this productHow old are you? 30-39What is your skin type? NormalWhat is your skin tone? FairWhat are your skin concerns? Sensitivity, Redness, Dryness, Pigmentation, WrinklesRated 5 out of 5 stars5 months ago3rd repurchase
This is my third repurchase. This is the best vit c serum. And it has the added benefit of helping me clear break outs quickly.
Was this helpful? - LBLisa B.Verified BuyerReviewingiS Clinical Pro-Heal Serum Advance+I recommend this productHow old are you? 40-49What is your skin type? DryWhat is your skin tone? FairWhat are your skin concerns? Ageing, Sensitivity, WrinklesRated 5 out of 5 stars5 months agoPretty good
I read reviews that this was more gentle than other vitamin C brands, so I thought I would try it as I have sensitive skin. I use sparingly because it seems strong. I don’t notice a difference, but do like being able to use a Vitamin C without a reaction
Was this helpful? - LFLisa F.Verified BuyerReviewingiS Clinical Pro-Heal Serum Advance+I recommend this productHow old are you? 40-49What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Acne, Ageing, Redness, Sensitivity, WrinklesRated 5 out of 5 stars10 months agoBest Vitamin C Product!
Amazing product! My skin is so much better after using it. Love this product.
Was this helpful? - VCVivian C.Verified BuyerReviewingiS Clinical Pro-Heal Serum Advance+I recommend this productHow old are you? 30-39What is your skin type? CombinationWhat is your skin tone? TanWhat are your skin concerns? Redness, Acne, Ageing, Pigmentation, Sun DamageRated 4 out of 5 stars1 year agoVit c obsessed
I love the “non” smell vitamin c has. It makes my skin so bright and the pores smaller.
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