iS Clinical Retinol+ Emulsion 0.3%
This innovative 0.3% retinol emulsion is formulated with iS Clinical’s proprietary Extremozyme® technology and is encapsulated with bio-identical lipids for a dynamic delivery system. A triad of boosters that include rice bran, vitamin E, and rosemary increases the potency of the retinol by more than 30% while also acting as a natural preservative. The addition of supporting ingredients such as vitamin C, shea butter, peptides, and mushroom extract boost cell turnover benefits and provide the skin with vital nutrition and anti-inflammatory benefits, making this the ultimate, well-rounded all-star in your skincare lineup.
- Provides mild exfoliation
- Diminishes fine lines and wrinkles
- Increases firmness and elasticity
- Promotes a more even tone and texture
- Improves dull complexion
- Reduces effects from environmental damage
- Protects with DNA-repairing (Extremeozyme®) technology
- 6.0 pH +/- 0.5
1 oz | Airless Pump
Those looking for a well-rounded formulation of retinol to treat fine lines and wrinkles, promote a more even skin tone, and improve texture while providing vital nutrition using a unique delivery system.
In Clinical Studies, iS Clinical Retinol+ Emulsion 0.3% is proven to:
- Improve Fine Lines and Wrinkles by 22% after 84 days
- Improve Skin Elasticity by 22% after 84 days
- Improve Skin Hydration by 18% after 84 days
- Strongly activate genes involved in the maintenance and repair of the Dermal Epidermal Junction (DEJ)*, for important anti-aging and wound-healing applications.
*The DEJ is the important attachment between the epidermis and the dermis and is vital for the structure of the skin
We recommend following the iS Clinical boosted nighttime routine for renewed texture and glow:
Step 1: iS Clinical Youth Serum
Step 2: iS Clinical Retinol Emulsion 0.3%
Step 3: For Combo/Normal Skin Types: iS Clinical Reparative Moisture Emulsion; For Dry Skin Types: iS Clinical SHEALD Recovery Balm
After cleansing and toning apply 2-3 pumps to face, neck, and chest in the evening only, layer with your favorite moisturizer. Be sure to add SPF protection in the AM when using this product, as retinol increases sensitivity to the sun.
*Use every 3 days for 3 weeks, then if well tolerated, bump up application to every other evening.
- Retinol (0.3%): A derivative of vitamin A that provides exfoliation and stimulates collagen production, reducing the appearance of fine lines and wrinkles.
- Shea Butter: Softens, seals in moisture, and helps protect against environmental damage.
- Bakuchiol: A plant-based retinol alternative that promotes a vibrant, refined, taut, and renewed complexion.
- Rice Bran Extract: Clarifies the skin with nourishing, hydrating, and brightening benefits.
- Rosemary Leaf Extract: A powerful antioxidant that provides anti-inflammatory and anti-microbial benefits with a clarifying boost.
- Vitamin E (Tocopherol): Soothes, brightens, and helps reverse and protect against environmental damage.
- Ectoin: Works to provide a protective shield for the skin and is a natural moisture binder, improving the health of the skin barrier and protecting against transepidermal water loss.
- Colloidal Gold: Formed by suspending small gold particles in liquid so it is biologically usable by the body. Calms inflammation, increases elasticity, and reduces the appearance of fine lines and wrinkles.
- Copper Tripeptide-1: Contains three amino acids (glycine, histidine, and lysine) combined with the mineral copper. Supports healing and regeneration, boosts collagen synthesis, and delivers beneficial epigenetic messages to cells.
- Poria Cocos Extract: A mushroom extract well-known for its ability to reduce the appearance of aging skin, boost collagen synthesis, and reduce inflammation.
- Squalane: Keeps skin hydrated and balances oil production by mimicking the skin’s acid mantle while also reducing inflammation, soothing skin irritation, and improving elasticity.
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/ Lactate/ Linoleate/ Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/ Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.
iS Clinical Retinol+ Emulsion 0.3% is a highly active, encapsulated retinol cream that provides mild exfoliating benefits to reduce fine lines and wrinkles, promote a more even skin tone, and improve overall texture.
- Unit price
- /per
Primary Concerns:
- Wrinkles
- Large Pores
- Fine Lines
- Loss of Firmness
- Sun Damage
Best For:
- Combination
- Dry
- Normal
- Oily
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iS Clinical Retinol+ Emulsion 0.3%
This innovative 0.3% retinol emulsion is formulated with iS Clinical’s proprietary Extremozyme® technology and is encapsulated with bio-identical lipids for a dynamic delivery system. A triad of boosters that include rice bran, vitamin E, and rosemary increases the potency of the retinol by more than 30% while also acting as a natural preservative. The addition of supporting ingredients such as vitamin C, shea butter, peptides, and mushroom extract boost cell turnover benefits and provide the skin with vital nutrition and anti-inflammatory benefits, making this the ultimate, well-rounded all-star in your skincare lineup.
- Provides mild exfoliation
- Diminishes fine lines and wrinkles
- Increases firmness and elasticity
- Promotes a more even tone and texture
- Improves dull complexion
- Reduces effects from environmental damage
- Protects with DNA-repairing (Extremeozyme®) technology
- 6.0 pH +/- 0.5
1 oz | Airless Pump
Those looking for a well-rounded formulation of retinol to treat fine lines and wrinkles, promote a more even skin tone, and improve texture while providing vital nutrition using a unique delivery system.
In Clinical Studies, iS Clinical Retinol+ Emulsion 0.3% is proven to:
- Improve Fine Lines and Wrinkles by 22% after 84 days
- Improve Skin Elasticity by 22% after 84 days
- Improve Skin Hydration by 18% after 84 days
- Strongly activate genes involved in the maintenance and repair of the Dermal Epidermal Junction (DEJ)*, for important anti-aging and wound-healing applications.
*The DEJ is the important attachment between the epidermis and the dermis and is vital for the structure of the skin
We recommend following the iS Clinical boosted nighttime routine for renewed texture and glow:
Step 1: iS Clinical Youth Serum
Step 2: iS Clinical Retinol Emulsion 0.3%
Step 3: For Combo/Normal Skin Types: iS Clinical Reparative Moisture Emulsion; For Dry Skin Types: iS Clinical SHEALD Recovery Balm
After cleansing and toning apply 2-3 pumps to face, neck, and chest in the evening only, layer with your favorite moisturizer. Be sure to add SPF protection in the AM when using this product, as retinol increases sensitivity to the sun.
*Use every 3 days for 3 weeks, then if well tolerated, bump up application to every other evening.
- Retinol (0.3%): A derivative of vitamin A that provides exfoliation and stimulates collagen production, reducing the appearance of fine lines and wrinkles.
- Shea Butter: Softens, seals in moisture, and helps protect against environmental damage.
- Bakuchiol: A plant-based retinol alternative that promotes a vibrant, refined, taut, and renewed complexion.
- Rice Bran Extract: Clarifies the skin with nourishing, hydrating, and brightening benefits.
- Rosemary Leaf Extract: A powerful antioxidant that provides anti-inflammatory and anti-microbial benefits with a clarifying boost.
- Vitamin E (Tocopherol): Soothes, brightens, and helps reverse and protect against environmental damage.
- Ectoin: Works to provide a protective shield for the skin and is a natural moisture binder, improving the health of the skin barrier and protecting against transepidermal water loss.
- Colloidal Gold: Formed by suspending small gold particles in liquid so it is biologically usable by the body. Calms inflammation, increases elasticity, and reduces the appearance of fine lines and wrinkles.
- Copper Tripeptide-1: Contains three amino acids (glycine, histidine, and lysine) combined with the mineral copper. Supports healing and regeneration, boosts collagen synthesis, and delivers beneficial epigenetic messages to cells.
- Poria Cocos Extract: A mushroom extract well-known for its ability to reduce the appearance of aging skin, boost collagen synthesis, and reduce inflammation.
- Squalane: Keeps skin hydrated and balances oil production by mimicking the skin’s acid mantle while also reducing inflammation, soothing skin irritation, and improving elasticity.
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/ Lactate/ Linoleate/ Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/ Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.
Explore More Recommendations
iS Clinical Retinol+ Emulsion 0.3%
- DSDebbie S.Verified BuyerReviewingiS Clinical Retinol+ Emulsion 0.3%I recommend this productHow old are you? Over 65Rated 5 out of 5 stars5 months agoiS Clinical Retinol+ Emulsion 0.3%
Gentle for a retinol
I just started using the IS CLINICAL retinol emulsion. I like how it doesn't dry my skin out as much as other retinols I've used. I've only been using it 2 weeks and so far so good. I'll give another update once I've used it for longer.
Was this helpful? - ASAllison S.Verified BuyerReviewingiS Clinical Retinol+ Emulsion 0.3%I recommend this productHow old are you? 40-49Rated 5 out of 5 stars5 months agoiS Clinical Retinol+ Emulsion 0.3%
Love this retinol. Has not
Love this retinol. Has not given me any issues at all. Mild but effective.
Was this helpful? - LWLinell W.Verified BuyerReviewingiS Clinical Retinol+ Emulsion 0.3%I recommend this productHow old are you? 50-65Rated 5 out of 5 stars5 months agoiS Clinical Retinol+ Emulsion 0.3%
Reduce Fine Lines.
I think this helps with fine lines. Have backed off this summer.
Was this helpful? - MVMelissa V.Verified BuyerReviewingiS Clinical Retinol+ Emulsion 0.3%I recommend this productHow old are you? 50-65Rated 5 out of 5 stars5 months agoiS Clinical Retinol+ Emulsion 0.3%
Gentle
My favorite new find from iS Clinical. Luxurious and creamy texture. Absorbs quickly. I apply one small pump of this retinol in the evening as my final step in my skincare routine. Skin feels hydrated and sealed for bedtime. In the morning my skin feels soft and supple, and looks radiant. I am very happy with my results from the iS Clinical line. Look forward to experimenting with whatever they produce.
Was this helpful? - SYSuzanne Y.Verified BuyerReviewingiS Clinical Retinol+ Emulsion 0.3%I recommend this productHow old are you? Over 65Rated 5 out of 5 stars5 months agoiS Clinical Retinol+ Emulsion 0.3%
The Retinal is very gentle
The Retinal is very gentle to the skin..I started using it a month ago, 3 times a week...to introduce it to skin..All good to go to use daily now at night. Skins feeling and looking better. Glad I started using it ..
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Why Art of Skincare?
At Art of Skincare we don’t believe in a one-size-fits-all approach. Our philosophy is to meet you where you are and partner with you to create results that work for your individual needs. We exist to inspire you to experience your most radiant and unique self. From acne solutions to healthy aging routines, our team of seasoned estheticians will be here every step of the way. Art of Skin Care is more than just a skincare brand. It’s a journey, a lifestyle, and, most importantly, a commitment to the unique beauty of each individual.