Senté Dermal Repair Ultra-Nourish

Senté Dermal Repair Ultra-Nourish is a deeply restorative moisturizer built around Senté's patented Heparan Sulfate Analog (HSA) technology, a triple ceramide complex, and concentrated barrier-restoring lipids to deliver rescue-level hydration for very dry, dehydrated, or barrier-compromised skin. It addresses the persistent tightness, roughness, and sensitivity that come from chronic dryness, over-exfoliation, post-procedure healing, or harsh seasonal conditions. This fragrance-free formula works as a daily moisturizer for extremely dry skin or as an intensive overnight treatment when your barrier needs serious repair.

Restores and Reinforces the Skin Barrier: A triple ceramide complex (ceramide NP, ceramide AP, ceramide EOP) combined with phytosphingosine, cholesterol, and phytosterols rebuilds the skin's natural lipid structure, locking in moisture and reducing the chronic water loss behind persistent dryness and sensitivity.

Delivers Deep, Sustained Hydration: Glycerin, squalene, jojoba/macadamia seed oil esters, and camelina sativa seed oil create a concentrated emollient base that keeps skin continuously hydrated throughout the day and overnight, eliminating the tight, flaky feeling that lighter moisturizers leave behind.

Calms Inflammation and Skin Reactivity: Heparan Sulfate Analog reduces inflammation at a cellular level, making this formula especially well suited for skin recovering from aggressive treatments, over-exfoliation, or conditions like rosacea where chronic reactivity undermines barrier health.

Supports Natural Skin Renewal: HSA encourages the skin's own repair cycle, progressively improving texture, resilience, and overall skin quality with continued use, so your barrier grows stronger rather than just temporarily patched.

Fragrance-Free and Gentle for Reactive Skin: Free of fragrance and common irritants, with a formula gentle enough for eczema-prone, rosacea-affected, and post-procedure skin where minimizing irritation is essential.

In a clinical study over 2 weeks:

• 95% of subjects agreed that their skin felt more nourished
• 94% of subjects agreed that their skin was less dry

*Data on file, Sente

Senté Dermal Repair Ultra-Nourish is made for skin that needs more than a standard moisturizer can deliver. If your skin feels perpetually tight, rough, or flaky despite regular moisturizing, or if you are managing a compromised barrier from over-exfoliation, harsh treatments, or environmental damage, this is the formula that addresses those concerns directly.

It is also an excellent choice for mature skin that has lost significant natural lipid content, as well as for anyone experiencing post-procedure dryness after chemical peels, laser resurfacing, or intensive facials. The fragrance-free, ceramide-rich formula is gentle enough for eczema-prone or rosacea-affected skin, where barrier repair is the foundation before any corrective treatment can begin.

If you live in a dry or cold climate and find that standard moisturizers fall short through the winter months, Senté Dermal Repair Ultra-Nourish delivers the deep, lasting hydration that thinner formulas cannot provide.

Layer Senté Dermal Repair Ultra-Nourish as the final step in your evening routine over active serums to create an occlusive seal that locks everything in. Clients with very dry or compromised skin see the fastest barrier recovery when this cream is pressed into slightly damp skin, trapping surface moisture and driving deeper hydration all night.

Prepare: Apply to clean skin after serums and treatments, morning and evening. For best results, apply while skin is slightly damp to boost moisture absorption.

Apply: Warm a generous amount between the palms and press gently into the face, neck, and any areas of particular dryness or irritation.

Technique: Use upward pressing motions rather than rubbing to avoid disrupting sensitized or compromised skin. Can be applied in a thicker layer as an overnight mask for intensive repair.

Frequency: Use morning and evening as a daily moisturizer, or apply at night as an intensive overnight treatment. In the morning, follow with a broad-spectrum SPF of 30 or higher.

We offer free shipping on every order $50+ (just $7 flat-rate below that). Orders placed before 1pm PST Monday through Friday ship out the same day. Orders placed outside of that window are shipped the very next business day!

Changed your mind? We get it. That's why our return window is generous: 30 days even if you've opened and tried it, or a full 60 days if it's still sealed. Some exclusions apply. See our full return policy for details.