NeoGenesis Barrier Renewal Cream

The NeoGenesis Barrier Renewal Cream is a moisturizer booster designed to lock in hydration and strengthen the skin barrier, preventing transepidermal water loss (TEWL). Formulated with the perfect balance of ceramides and cholesterol-free fatty acids, this lightweight yet powerful finishing layer helps seal in moisture for long-lasting hydration and improved skin resilience.

Designed to be used over your favorite hydrating moisturizer, this barrier-fortifying cream is ideal for dry, sensitive, rosacea-prone, and compromised skin. With regular use, it supports skin repair, reduces irritation, and enhances firmness, making it a must-have for moisture retention and overall skin health.

  • Boosts hydration retention by sealing in moisture
  • Strengthens and repairs the skin barrier to prevent moisture loss
  • Provides essential ceramides and lipids for long-term resilience
  • Lightweight, non-greasy formula, perfect as a finishing layer
  • Unscented and oncology-approved, safe for even the most sensitive skin

30 mL | Airless Pump

120 mL or 5 mL | Pump

Acne Safe

NeoGenesis Barrier Renewal Cream

NeoGenesis Barrier Renewal Cream – The Ultimate Moisture Lock Booster

4.8
Rated 4.8 out of 5 stars
232 Reviews
Regular price $52.00
Unit price
per 
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Compromised Barrier
  • Dehydration
  • Dryness
  • Dullness
  • Redness/Rosacea
Lotion bottle icons

Best For:

  • Dry
  • Normal
  • Sensitive

NeoGenesis Barrier Renewal Cream

The NeoGenesis Barrier Renewal Cream is a moisturizer booster designed to lock in hydration and strengthen the skin barrier, preventing transepidermal water loss (TEWL). Formulated with the perfect balance of ceramides and cholesterol-free fatty acids, this lightweight yet powerful finishing layer helps seal in moisture for long-lasting hydration and improved skin resilience.

Designed to be used over your favorite hydrating moisturizer, this barrier-fortifying cream is ideal for dry, sensitive, rosacea-prone, and compromised skin. With regular use, it supports skin repair, reduces irritation, and enhances firmness, making it a must-have for moisture retention and overall skin health.

  • Boosts hydration retention by sealing in moisture
  • Strengthens and repairs the skin barrier to prevent moisture loss
  • Provides essential ceramides and lipids for long-term resilience
  • Lightweight, non-greasy formula, perfect as a finishing layer
  • Unscented and oncology-approved, safe for even the most sensitive skin

30 mL | Airless Pump

120 mL or 5 mL | Pump

NeoGenesis Barrier Renewal Cream

4.8
Rated 4.8 out of 5 stars
Based on 232 reviews
Total 5 star reviews: 201 Total 4 star reviews: 20 Total 3 star reviews: 11 Total 2 star reviews: 0 Total 1 star reviews: 0
232 reviews
  • KU
    Karen U.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 50-65
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Pigmentation, Wrinkles, Sun Damage
    Rated 5 out of 5 stars
    1 month ago
    Very Nice

    This is a great daytime moisturizer. I use it on before my sun screen.

  • KW
    Karolina W.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 30-39
    What is your skin type? Oily
    What is your skin tone? Medium
    What are your skin concerns? Oiliness, Acne
    Rated 5 out of 5 stars
    2 months ago
    Barrier renewal cream

    It's amazing product I love my skin

  • GC
    Gina C.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 50-65
    What is your skin type? Combination
    What is your skin tone? Medium
    What are your skin concerns? Blemish-prone, Ageing, Wrinkles, Pigmentation, Sensitivity
    Rated 5 out of 5 stars
    5 months ago
    Love

    I really love this cream. It is very hydrating without being heavy.

    It goes on nice and feels good on the skin. It has also helped my dry itchy skin I was experiencing at the base of my neck.

  • P
    Patty
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 30-39
    What is your skin type? Dry
    What is your skin tone? Medium
    What are your skin concerns? Dryness, Sensitivity, Redness, Blemish-prone, Ageing
    Rated 5 out of 5 stars
    5 months ago
    Amazing Cream Moisturizer for Dry Skin

    I love this product so much! This cream definitely helped my dry skin. I have tried face reality and skinscript moisturizers, while they are really great & credible brands, none of their moisturizer had helped me with my dry skin. With the NeoGenesis Barrier Cream you don't have to use a whole ton of product. The 30ml will last me 2.5 months! Worth the price.

  • P
    Pam
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? Over 65
    What is your skin type? Dry
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Sensitivity, Dryness, Wrinkles
    Rated 5 out of 5 stars
    7 months ago
    Really effective moisturizer & barrier cream

    The ingredients in this cream are exactly what my mature, dry, dehydrated skin craves. It is not a heavy cream application, but it remains supremely nourishing and protective on top of my serums. I especially love using it at night because it keeps my skin moist and supple and seals in all my serums while I sleep. (Since I am a side-sleeper, that is critical.) When I awake in the morning, my skin feels and looks great.

Why Art of Skin Care?

At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.