iS Clinical Brightening Complex

iS Clinical Brightening Complex takes a holistic, science-backed approach to enhancing skin brightness and overall health. This powerful daytime formula utilizes pharmaceutical-grade botanicals, stabilized vitamin C, and advanced DNA-repairing enzymes (Extremozymes) to visibly diminish dark spots, even out skin tone, and promote long-term skin resilience.

Designed to work synergistically with iS Clinical Brightening Serum, this duo creates a complete AM/PM regimen for tackling hyperpigmentation, rough texture, and dullness. Use the Brightening Complex in the morning to protect, hydrate, and prepare the skin, then follow with the Brightening Serum at night for gentle exfoliation and deeper pigment correction.

Tip: Many normal to oily skin types enjoy Brightening Complex as their daytime moisturizer, thanks to its lightweight, fast-absorbing texture and multi-action benefits.

  • Brightens and evens skin tone
  • Diminishes dark spots and hyperpigmentation
  • Provides gentle exfoliation for a smoother texture
  • Deeply hydrates and supports barrier health
  • Defends against environmental damage with Extremozymes®
  • Ideal AM partner to iS Clinical Brightening Serum
  • pH 3.3 ± 0.5

1 oz | Airless Pump

Acne Safe

iS Clinical Brightening Complex

A multitasking morning treatment that brightens, hydrates, and protects, while setting the stage for your evening brightening routine.

4.6
Rated 4.6 out of 5 stars
14 Reviews
Regular price $159.00
Unit price
per 
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Dullness
  • Pigmentation
  • Sun Damage
  • Fine Lines
Lotion bottle icons

Best For:

  • Combination
  • Dry
  • Normal
  • Oily

iS Clinical Brightening Complex

iS Clinical Brightening Complex takes a holistic, science-backed approach to enhancing skin brightness and overall health. This powerful daytime formula utilizes pharmaceutical-grade botanicals, stabilized vitamin C, and advanced DNA-repairing enzymes (Extremozymes) to visibly diminish dark spots, even out skin tone, and promote long-term skin resilience.

Designed to work synergistically with iS Clinical Brightening Serum, this duo creates a complete AM/PM regimen for tackling hyperpigmentation, rough texture, and dullness. Use the Brightening Complex in the morning to protect, hydrate, and prepare the skin, then follow with the Brightening Serum at night for gentle exfoliation and deeper pigment correction.

Tip: Many normal to oily skin types enjoy Brightening Complex as their daytime moisturizer, thanks to its lightweight, fast-absorbing texture and multi-action benefits.

  • Brightens and evens skin tone
  • Diminishes dark spots and hyperpigmentation
  • Provides gentle exfoliation for a smoother texture
  • Deeply hydrates and supports barrier health
  • Defends against environmental damage with Extremozymes®
  • Ideal AM partner to iS Clinical Brightening Serum
  • pH 3.3 ± 0.5

1 oz | Airless Pump

iS Clinical Brightening Complex

4.6
Rated 4.6 out of 5 stars
Based on 14 reviews
Total 5 star reviews: 11 Total 4 star reviews: 2 Total 3 star reviews: 0 Total 2 star reviews: 1 Total 1 star reviews: 0
14 reviews
  • MG
    Marci G.
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 50-65
    What is your skin type? Normal
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Wrinkles
    Rated 5 out of 5 stars
    1 month ago
    Great product

    Feels very nice on skin. Haven’t noticed a big difference in brightening however I am using in connection with the IS Clinical Peel. The peel at night and this is the AM. IS Clinical makes amazing effective products

  • JA
    Jason A.
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 40-49
    What is your skin type? Combination
    What is your skin tone? Tan
    What are your skin concerns? Ageing, Pigmentation, Redness, Sensitivity, Wrinkles
    Rated 5 out of 5 stars
    2 months ago
    Amazing

    Amazing product! I look and feel healthier and younger! That is amazing.

  • HR
    Hilary R.
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I do not recommend this product
    How old are you? 30-39
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Acne, Ageing, Pigmentation, Blemish-prone
    Rated 2 out of 5 stars
    3 months ago
    Caused Breakouts

    I wanted to love this serum as I could see some brightening effects taking place and was looking for something a bit more hydrating. However, within a week I noticed I was getting clogged pores and acne around my mouth and chin. I should have checked the ingredients more thoroughly as Ascophyllum Nodosum Extract is a pore clogging ingredient.

  • KV
    Kelli V. V.
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 50-65
    What is your skin type? Dry
    What is your skin tone? Medium
    What are your skin concerns? Ageing, Pigmentation, Sun Damage
    Rated 5 out of 5 stars
    5 months ago
    Impressive

    I have only been using this for 2 weeks per MJ's recommendation for my hyperpigmentation. I already see an improvement along with color science serum.

  • AS
    Allison S.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Brightening Complex
    I recommend this product
    How old are you? 40-49
    Rated 5 out of 5 stars
    1 year ago
    iS Clinical Brightening Complex

    Slight burning after applying. Have

    Slight burning after applying. Have not had any other issues.

Why Art of Skin Care?

At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.