Rhonda Allison Peptide 38

Rhonda Allison Peptide 38 is a targeted peptide serum formulated to visibly reduce the appearance of fine lines, deep wrinkles, and loss of firmness caused by photo-aging, environmental exposure, and the natural aging process. At the center of this formula is palmitoyl tripeptide-38, sold under the trademarked name Matrixyl Synthe'6, a peptide clinically shown to stimulate the synthesis of six key components of the skin matrix including collagen I, III, and IV, fibronectin, hyaluronic acid, and laminin 5, addressing the structural causes of aging rather than just the surface appearance. This serum carries a warm, grounding scent from lavender, patchouli, sandalwood, cedar, and orange peel oils.

Key Benefits

Visibly Reduces Fine Lines and Deep Wrinkles Palmitoyl tripeptide-38 (Matrixyl Synthe'6) works by stimulating six structural proteins in the skin matrix, targeting both surface lines and deeper wrinkles at their source.

Supports Collagen and Elastin Production By signaling fibroblast activity, Matrixyl Synthe'6 helps restore the collagen and elastin your skin produces less of with age and UV exposure, improving firmness and structural resilience over time.

Restores Hyaluronic Acid in the Skin Matrix Unlike a topical hyaluronic acid, this formula uses peptide signaling to encourage the skin to rebuild its own hyaluronic acid reserves within the dermal matrix, supporting plumpness from within.

Neuropeptide Anti-Wrinkle Action Acetyl hexapeptide-30 delivers a neuropeptide-like effect, helping to soften the appearance of expression lines by relaxing repetitive facial muscle tension over time.

Antioxidant and Hydration Support Goji berry fruit extract delivers antioxidant protection against environmental stressors, while glycerin and glycosaminoglycans help maintain hydration levels and support the skin's natural barrier function.

Peptide 38 is ideal for anyone dealing with visible signs of photo-aging including fine lines, deep wrinkles, loss of firmness, or skin that feels thin and less resilient than it used to. If years of sun exposure, environmental stress, or an inconsistent skincare routine have left your skin looking aged beyond where you want it, this serum addresses the structural reasons why.

This serum works well for normal, dry, combination, and mature skin types. It is also a strong choice for anyone who has done laser, resurfacing, or professional treatments and wants to support long-term collagen rebuilding between appointments.

If your skin is sensitive but still showing significant signs of aging, the gluconolactone in this formula offers a gentle touch of exfoliation without the irritation of stronger acids, making it a well-tolerated option even for reactive skin.

For best results with Peptide 38, be consistent with nightly use rather than applying it occasionally. Peptide-based formulas work cumulatively, meaning the collagen and elastin benefits build over weeks of steady use, so giving it a full 8 to 12 weeks before judging results will give you a much clearer picture of what it can do for your skin.

Frequency: Use in the evening as part of your PM routine.

Prepare: Apply to clean, dry skin after cleansing and any toning steps.

Apply: Dispense 1-2 pumps onto fingertips.

Technique: Gently massage into the face and neck until fully absorbed. Follow with your moisturizer.