Skinbetter AlphaRet Overnight Cream is a 16-time award-winning anti-aging night cream built around patented AlphaRet Technology, which bonds a retinoid (ethyl lactyl retinoate) directly to an alpha hydroxy acid (lactic acid) at the molecular level. Unlike traditional retinol creams that deliver a retinoid and an exfoliant separately, this patented conjugate works as a single molecule, delivering visible improvement in lines, wrinkles, uneven tone, and rough texture while producing little-to-no irritation. The formula is fragrance-free, paraben-free, and dye-free.

Key Benefits

Reduces Wrinkles and Fine Lines with Minimal Irritation
Patented AlphaRet Technology fuses a retinoid and an AHA into a single molecule, significantly reducing the appearance of wrinkles in as little as four weeks without the redness and peeling common with conventional retinoids.

Brightens and Evens Skin Tone
Glycolic acid and tetrahexyldecyl ascorbate (a stable, lipid-soluble form of vitamin C) work together to refine tone, reduce dullness, and fade the look of discoloration over time.

Strengthens the Skin Barrier While You Sleep
Niacinamide, ceramide NP, squalane, and shea butter reinforce the moisture barrier, while portulaca oleracea extract and bisabolol help calm and soothe skin, counteracting the dryness that retinoid-based products often cause.

Supports Firmer-Looking, Resilient Skin
Peptides palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, combined with the antioxidants ubiquinone (CoQ10) and superoxide dismutase, help defend against environmental stress and promote a visibly firmer appearance.

Keeps Skin Hydrated and Comfortable Overnight
Hyaluronic acid, panthenol, glycerin, and allantoin attract and lock in moisture so skin feels soft and calm by morning.

33% Reduction of fine lines and wrinkles after 12 weeks*

28% Reduction of the appearance of visible skin redness after 12 weeks*

Patient Satisfaction

97% of users agree AlphaRet feels gentle enough for daily use*

*A 12-week split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging. N=48.

If fine lines, wrinkles, uneven tone, or rough texture are your primary concerns and you want the benefits of a retinoid without the harsh adjustment period, this cream was designed for you. It is especially well-suited for anyone who has tried traditional retinol products in the past and experienced excessive dryness, flaking, or irritation. If you're trying a retinoid for the first time, this is one of the most approachable options available.

All skin types can benefit, including sensitive skin that typically cannot tolerate retinoids. If you already use active exfoliants, introduce this cream gradually and monitor your skin's response to avoid over-exfoliation.

Pair this cream with a hydrating serum containing hyaluronic acid applied underneath on the nights you use it. The extra layer of hydration helps buffer any initial sensitivity and keeps your skin barrier supported while the AlphaRet Technology does its work overnight.

Apply: After cleansing and any treatment serums, smooth a thin layer over the entire face, avoiding the eye area.

Frequency: Use every evening as part of your nighttime skincare routine. If you are new to retinoid products, start with every other night for the first two weeks, then increase to nightly use as tolerated.

Protect: Apply a broad-spectrum sunscreen every morning. AHA ingredients increase sun sensitivity, so consistent daily SPF protection is essential while using this cream.