Senté Hydrate+ Serum
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Senté Hydrate+ Serum is a multi-weight hyaluronic acid serum built on Senté's patented Heparan Sulfate Analog (HSA) technology to deliver hydration that reaches beyond the skin's surface. Rather than relying on a single form of hyaluronic acid, this lightweight, fast-absorbing formula combines sodium hyaluronate, sodium acetylated hyaluronate, hydrolyzed sodium hyaluronate, and sodium hyaluronate crosspolymer to target multiple layers of the skin simultaneously, plumping dehydration lines, reinforcing moisture retention, and creating a visibly smoother, more comfortable complexion.
Multi-Depth Hydration from Four Forms of Hyaluronic Acid: Different molecular weights of hyaluronic acid saturate multiple layers of the skin at once, delivering immediate surface plumping while drawing lasting hydration into deeper tissue where dehydration lines originate.
Longer-Lasting Moisture Retention with HSA: Senté's patented Heparan Sulfate Analog supports the skin's ability to hold onto moisture at a cellular level, so hydration benefits build over time rather than evaporating after application.
Visible Reduction in Dehydration Lines: The concentrated hyaluronic acid complex fills in fine lines caused by moisture loss within minutes of application, creating a smoother, more rested appearance that improves with continued use.
Barrier-Strengthening Support: Panthenol and biosaccharide gum-1 work alongside the hyaluronic acid complex to calm the skin and reinforce the moisture barrier, reducing the cycle of chronic tightness and dehydration.
Lightweight, Layer-Friendly Formula: The water-based texture absorbs quickly with no residue, making it compatible with every skin type, moisturizer, and SPF without adding heaviness or contributing to breakouts.
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Senté Hydrate+ Serum is ideal for anyone whose skin feels tight, looks flat, or shows fine lines that worsen with dryness rather than age. If your skin still feels thirsty shortly after moisturizing, a dedicated hydrating serum addresses the deeper moisture deficit that a moisturizer alone cannot fix.
It works across all skin types, including oily and combination skin that is dehydrated beneath a surface layer of excess oil. Because the formula is lightweight and non-occlusive, it layers seamlessly under any moisturizer or SPF without adding heaviness or triggering congestion.
This serum is also a strong choice for anyone using retinol, chemical exfoliants, or other corrective actives that can deplete hydration, as well as anyone preparing their skin for professional treatments like chemical peels or microneedling, where well-hydrated skin responds more effectively and recovers faster.
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Apply Senté Hydrate+ Serum to skin that is still slightly damp from cleansing or toning. Hyaluronic acid draws moisture from the environment and surrounding layers, so applying it to damp skin ensures it pulls that surface water inward rather than drawing from deeper tissue, giving you a noticeably plumper, more comfortable result.
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Prepare: Apply to clean, slightly damp skin morning and evening after cleansing and toning, before moisturizer.
Apply: Dispense 5 to 7 drops into the palm of your hand and gently press the serum across the face, neck, and décolleté.
Technique: Use pressing and patting motions rather than rubbing to allow the hyaluronic acid complex to absorb evenly. Follow immediately with a moisturizer to seal in the hydration.
Frequency: Use morning and evening for best results. In the morning, layer beneath your moisturizer and broad-spectrum SPF. Always seal hyaluronic acid serums with a moisturizer to prevent moisture from evaporating back out of the skin.
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Key Ingredients
- Heparan Sulfate Analog (HSA): Senté's breakthrough patented molecule is clinically proven to go beyond surface hydration to deeply replenish moisture, reduce visible redness, and support the skin's natural ability to repair itself at a cellular level, delivering profound and lasting rejuvenation.
- Multi-Weight Hyaluronic Acid: A blend of hyaluronic acid molecules in varying sizes that hydrate multiple layers of the skin at once. This complex draws in lasting moisture, plumps the appearance of fine lines, and helps maintain a soft, supple, well cushioned complexion.
- Beta Glucan: A deeply hydrating, barrier-strengthening ingredient that helps calm redness, support skin recovery, and improve resilience, making it ideal for sensitive or acne-prone skin.
Aqua/Water/Eau, Acetamidoethoxyethanol, Glycerin, Panthenol, Heparan Sulfate, Polyacrylate Crosspolymer-6, Sodium PCA, Hydroxyacetophenone, 1,2-Hexanediol, Caprylyl Glycol, Erythritol, *Carrageenan, Pentylene Glycol, Biosaccharide Gum-1, Sodium Carboxymethyl Beta-Glucan, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hydroxide, Sodium Hyaluronate Crosspolymer, Sodium Anisate, Hydrolyzed Sodium Hyaluronate, Sodium Levulinate, Citric Acid, Benzoic Acid, Xanthan Gum, Glyceryl Caprylate, Sorbic Acid, Disodium EDTA, Ethylhexylglycerin
*Refined to be acne safe. -
We offer free shipping on every order $50+ (just $7 flat-rate below that). Orders placed before 1pm PST Monday through Friday ship out the same day. Orders placed outside of that window are shipped the very next day!
Changed your mind? We get it. That's why our return window is generous: 30 days even if you've opened and tried it, or a full 60 days if it's still sealed. Some exclusions apply. See our full return policy for details. -
How is Senté Hydrate+ Serum different from a regular hyaluronic acid serum?
Most hyaluronic acid serums use one or two molecular weights of HA for surface-level plumping. Senté Hydrate+ Serum combines four forms of hyaluronic acid with Senté's patented Heparan Sulfate Analog (HSA), which supports long-term moisture retention at a cellular level. This means hydration benefits are both immediate and cumulative, improving the skin's ability to hold onto moisture over time rather than requiring constant reapplication.
Can I use Senté Hydrate+ Serum if I have oily skin?
Yes. Senté Hydrate+ Serum is lightweight and water-based, so it absorbs quickly without adding oiliness or heaviness. Dehydration is common even in oily skin and can actually trigger excess oil production, so adding a hydrating serum often helps balance the skin rather than making it oilier.
How many drops of Senté Hydrate+ Serum should I use per application?
Use 5 to 7 drops per application, pressed gently across the face and neck. This is typically enough for even coverage without oversaturating the skin. If you are also covering the décolleté, you may need an additional drop or two.
Should I apply Senté Hydrate+ Serum before or after my other serums?
Apply Senté Hydrate+ Serum after any water-based treatment serums and before oil-based serums or moisturizers. Lighter, water-based formulas absorb best when applied to clean or freshly treated skin first, with heavier textures layered on top to seal everything in.
Is Senté Hydrate+ Serum safe to use around the eye area?
Yes, the gentle, water-based formula is appropriate for use around the orbital bone and can help reduce the appearance of fine dehydration lines around the eyes. For more targeted concerns like dark circles or puffiness, pairing it with a dedicated eye treatment delivers the best results.
Can I use Senté Hydrate+ Serum with retinol or chemical exfoliants?
Absolutely. Senté Hydrate+ Serum is an excellent hydration layer for routines that include retinol, AHAs, BHAs, or other actives that can dry or sensitize the skin. Apply it after your actives and before your moisturizer to restore hydration and reduce the transient dryness that corrective treatments often cause.
How quickly will I see results with Senté Hydrate+ Serum?
Most users notice an immediate improvement in plumpness, comfort, and surface smoothness with the first application. Fine lines caused by dehydration visibly diminish within minutes. Cumulative improvements in overall skin texture and the skin's ability to retain moisture develop over 4 to 8 weeks of consistent use.
Why buy Senté Hydrate+ Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of Senté, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if Senté Hydrate+ Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
Senté Hydrate+ Serum is a multi-weight hyaluronic acid serum built on Senté's patented Heparan Sulfate Analog (HSA) technology to deliver hydration that reaches beyond the skin's surface. Rather than relying on a single form of hyaluronic acid, this lightweight, fast-absorbing formula combines sodium hyaluronate, sodium acetylated hyaluronate, hydrolyzed sodium hyaluronate, and sodium hyaluronate crosspolymer to target multiple layers of the skin simultaneously, plumping dehydration lines, reinforcing moisture retention, and creating a visibly smoother, more comfortable complexion.
Multi-Depth Hydration from Four Forms of Hyaluronic Acid: Different molecular weights of hyaluronic acid saturate multiple layers of the skin at once, delivering immediate surface plumping while drawing lasting hydration into deeper tissue where dehydration lines originate.
Longer-Lasting Moisture Retention with HSA: Senté's patented Heparan Sulfate Analog supports the skin's ability to hold onto moisture at a cellular level, so hydration benefits build over time rather than evaporating after application.
Visible Reduction in Dehydration Lines: The concentrated hyaluronic acid complex fills in fine lines caused by moisture loss within minutes of application, creating a smoother, more rested appearance that improves with continued use.
Barrier-Strengthening Support: Panthenol and biosaccharide gum-1 work alongside the hyaluronic acid complex to calm the skin and reinforce the moisture barrier, reducing the cycle of chronic tightness and dehydration.
Lightweight, Layer-Friendly Formula: The water-based texture absorbs quickly with no residue, making it compatible with every skin type, moisturizer, and SPF without adding heaviness or contributing to breakouts.
Senté Hydrate+ Serum is ideal for anyone whose skin feels tight, looks flat, or shows fine lines that worsen with dryness rather than age. If your skin still feels thirsty shortly after moisturizing, a dedicated hydrating serum addresses the deeper moisture deficit that a moisturizer alone cannot fix.
It works across all skin types, including oily and combination skin that is dehydrated beneath a surface layer of excess oil. Because the formula is lightweight and non-occlusive, it layers seamlessly under any moisturizer or SPF without adding heaviness or triggering congestion.
This serum is also a strong choice for anyone using retinol, chemical exfoliants, or other corrective actives that can deplete hydration, as well as anyone preparing their skin for professional treatments like chemical peels or microneedling, where well-hydrated skin responds more effectively and recovers faster.
Apply Senté Hydrate+ Serum to skin that is still slightly damp from cleansing or toning. Hyaluronic acid draws moisture from the environment and surrounding layers, so applying it to damp skin ensures it pulls that surface water inward rather than drawing from deeper tissue, giving you a noticeably plumper, more comfortable result.
Prepare: Apply to clean, slightly damp skin morning and evening after cleansing and toning, before moisturizer.
Apply: Dispense 5 to 7 drops into the palm of your hand and gently press the serum across the face, neck, and décolleté.
Technique: Use pressing and patting motions rather than rubbing to allow the hyaluronic acid complex to absorb evenly. Follow immediately with a moisturizer to seal in the hydration.
Frequency: Use morning and evening for best results. In the morning, layer beneath your moisturizer and broad-spectrum SPF. Always seal hyaluronic acid serums with a moisturizer to prevent moisture from evaporating back out of the skin.
- Heparan Sulfate Analog (HSA): Senté's breakthrough patented molecule is clinically proven to go beyond surface hydration to deeply replenish moisture, reduce visible redness, and support the skin's natural ability to repair itself at a cellular level, delivering profound and lasting rejuvenation.
- Multi-Weight Hyaluronic Acid: A blend of hyaluronic acid molecules in varying sizes that hydrate multiple layers of the skin at once. This complex draws in lasting moisture, plumps the appearance of fine lines, and helps maintain a soft, supple, well cushioned complexion.
- Beta Glucan: A deeply hydrating, barrier-strengthening ingredient that helps calm redness, support skin recovery, and improve resilience, making it ideal for sensitive or acne-prone skin.
Aqua/Water/Eau, Acetamidoethoxyethanol, Glycerin, Panthenol, Heparan Sulfate, Polyacrylate Crosspolymer-6, Sodium PCA, Hydroxyacetophenone, 1,2-Hexanediol, Caprylyl Glycol, Erythritol, *Carrageenan, Pentylene Glycol, Biosaccharide Gum-1, Sodium Carboxymethyl Beta-Glucan, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hydroxide, Sodium Hyaluronate Crosspolymer, Sodium Anisate, Hydrolyzed Sodium Hyaluronate, Sodium Levulinate, Citric Acid, Benzoic Acid, Xanthan Gum, Glyceryl Caprylate, Sorbic Acid, Disodium EDTA, Ethylhexylglycerin
*Refined to be acne safe.
We offer free shipping on every order $50+ (just $7 flat-rate below that). Orders placed before 1pm PST Monday through Friday ship out the same day. Orders placed outside of that window are shipped the very next day!
Changed your mind? We get it. That's why our return window is generous: 30 days even if you've opened and tried it, or a full 60 days if it's still sealed. Some exclusions apply. See our full return policy for details.
How is Senté Hydrate+ Serum different from a regular hyaluronic acid serum?
Most hyaluronic acid serums use one or two molecular weights of HA for surface-level plumping. Senté Hydrate+ Serum combines four forms of hyaluronic acid with Senté's patented Heparan Sulfate Analog (HSA), which supports long-term moisture retention at a cellular level. This means hydration benefits are both immediate and cumulative, improving the skin's ability to hold onto moisture over time rather than requiring constant reapplication.
Can I use Senté Hydrate+ Serum if I have oily skin?
Yes. Senté Hydrate+ Serum is lightweight and water-based, so it absorbs quickly without adding oiliness or heaviness. Dehydration is common even in oily skin and can actually trigger excess oil production, so adding a hydrating serum often helps balance the skin rather than making it oilier.
How many drops of Senté Hydrate+ Serum should I use per application?
Use 5 to 7 drops per application, pressed gently across the face and neck. This is typically enough for even coverage without oversaturating the skin. If you are also covering the décolleté, you may need an additional drop or two.
Should I apply Senté Hydrate+ Serum before or after my other serums?
Apply Senté Hydrate+ Serum after any water-based treatment serums and before oil-based serums or moisturizers. Lighter, water-based formulas absorb best when applied to clean or freshly treated skin first, with heavier textures layered on top to seal everything in.
Is Senté Hydrate+ Serum safe to use around the eye area?
Yes, the gentle, water-based formula is appropriate for use around the orbital bone and can help reduce the appearance of fine dehydration lines around the eyes. For more targeted concerns like dark circles or puffiness, pairing it with a dedicated eye treatment delivers the best results.
Can I use Senté Hydrate+ Serum with retinol or chemical exfoliants?
Absolutely. Senté Hydrate+ Serum is an excellent hydration layer for routines that include retinol, AHAs, BHAs, or other actives that can dry or sensitize the skin. Apply it after your actives and before your moisturizer to restore hydration and reduce the transient dryness that corrective treatments often cause.
How quickly will I see results with Senté Hydrate+ Serum?
Most users notice an immediate improvement in plumpness, comfort, and surface smoothness with the first application. Fine lines caused by dehydration visibly diminish within minutes. Cumulative improvements in overall skin texture and the skin's ability to retain moisture develop over 4 to 8 weeks of consistent use.
Why buy Senté Hydrate+ Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of Senté, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if Senté Hydrate+ Serum is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
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Senté Hydrate+ Serum
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- KLKsusha L.Verified ReviewerReviewingSenté Hydrate+ SerumI recommend this productHow old are you? 18-29What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Acne, Blemish-prone, Pigmentation, Redness, SensitivityRated 5 out of 5 starsYesterdayHoly Grail Tier
I am VERY expressive with my face, and I find after multiple hours of wearing makeup, I'll have little makeup expression lines on areas like my forehead, and my least of all favorite, the "bunny line" on the nose crease, which literally drives me nuts! Well, when I use this serum consistently, it just doesn't happen! It's honestly crazy because I thought I was doomed! This keeps my skin smooth, plump, and dehydration fine line free. I also love how supportive and reparative it is with the heparan sulfate analog. It helps my skin tolerate all my other potent active corrective products a lot better! Truly a staple in my routine. :)
Was this helpful? - SESusan E.Verified BuyerReviewingSenté Hydrate+ SerumI recommend this productHow old are you? 50-65What is your skin type? DryWhat is your skin tone? MediumWhat are your skin concerns? Sensitivity, Dryness, Ageing, Blemish-proneRated 5 out of 5 stars1 month agoAbsolutely love this!
I decided to give this a try as an alternative to the Hydrinity HA serums and am so glad I made the switch. This provides me with noticeable moisture that I find I wasn't getting from the Hydrinity products. Highly recommend!
Was this helpful? - EKElisabeth K.Verified BuyerReviewingSenté Hydrate+ SerumI recommend this productHow old are you? 50-65What is your skin type? NormalWhat is your skin tone? FairWhat are your skin concerns? Ageing, Sun Damage, WrinklesRated 5 out of 5 stars1 month agoFeels great!
As a big fan of HA, this product does not disappoint. I especially appreciate how light and nonsticky it is. I’ve had a small dry spot on my cheek which is almost gone after two weeks of use.
Was this helpful? - JjusticeVerified ReviewerReviewingSenté Hydrate+ SerumI recommend this productHow old are you? 30-39What is your skin type? DryWhat is your skin tone? FairWhat are your skin concerns? Acne, Ageing, Blemish-prone, Pigmentation, DrynessRated 5 out of 5 stars3 months agoNew favorite serum
I have used many HA serums in the past and nothing gives me the glow that this does! So soothing and hydrating. It might even replace a serum that costs 3x as much for me!
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