Senté Defense C Serum
Senté Defense C Serum is a nourishing vitamin C serum powered by THD Ascorbate and HSA to brighten, protect against environmental damage, and strengthen the skin's natural defenses.
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Senté Defense C Serum is a brightening and antioxidant vitamin C serum built for skin that needs both tone correction and genuine healing support. Powered by Tetrahexyldecyl Ascorbate, a stable oil-soluble form of vitamin C that penetrates more deeply than traditional formulas, alongside Senté's patented Heparan Sulfate Analog, it brightens dark spots, neutralizes daily environmental damage, and supports the skin's natural repair process in a single lightweight step. It works for all skin types, including those who have found conventional vitamin C serums too harsh or too unstable to trust.
Key Benefits
Brightens and Fades Dark Spots
Tetrahexyldecyl Ascorbate penetrates deeply to inhibit melanin production at the source, visibly fading sun damage, post-acne marks, and uneven tone over time.Heals and Repairs
HSA supports the skin's natural cellular repair cycle, helping to reduce visible redness, calm reactive skin, and restore a healthier, more even-looking complexion alongside the vitamin C.Antioxidant Defense Every Day
Neutralizes the free radical damage caused by UV exposure, pollution, and environmental stress that accumulates over time and accelerates visible aging.Supports Collagen Production
Vitamin C is a key cofactor in collagen synthesis, helping to maintain firmness and reduce the appearance of fine lines with consistent daily use.Stable and Skin-Friendly
Unlike L-ascorbic acid, Tetrahexyldecyl Ascorbate resists oxidation and does not cause the stinging or irritation that makes traditional vitamin C serums difficult to tolerate. -
In a clinical 8 week study:
- 94% of subjects showed improvement in skin brightness
- 87% of subjects showed improvement in skin evenness
- 87% of subjects showed improvement in skin luminosity
*Data on file, Sente
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Senté Defense C Serum is for anyone dealing with dullness, uneven skin tone, sun damage, or dark spots who wants real brightening results without the irritation that traditional vitamin C serums often bring. Because Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of vitamin C, it suits sensitive, rosacea-prone, and reactive skin types that have struggled with standard ascorbic acid formulas.
Dry skin types especially love this serum for the deeply hydrating, luminous finish it leaves behind, giving skin a healthy, lit-from-within glow rather than the tight or stripped feeling that water-based vitamin C formulas can cause.
It works beautifully as a morning serum layered beneath SPF for daily antioxidant protection, and pairs seamlessly with the rest of the Senté lineup for anyone focused on both brightening and long-term prevention.
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Apply Sente Defense C Serum every morning before SPF for maximum antioxidant benefit. Because IAA is stable and non-irritating, you can comfortably layer it with niacinamide, peptides, and even prescription actives without the reactivity that traditional L-ascorbic acid formulas sometimes cause.
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Prepare: Apply to clean, dry skin in the morning after cleansing and toning.
Apply: Dispense 3 to 5 drops into your palm or fingertips and gently press the serum into the face, neck, and upper chest.
Technique: Pat gently rather than rubbing to preserve the serum's integrity and encourage even absorption. Allow 30 to 60 seconds to absorb before applying the next step.
Frequency: Use every morning as part of your AM routine. Follow with a moisturizer and a broad-spectrum SPF of 30 or higher to maximize antioxidant protection throughout the day.
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Key Ingredients
- Vitamin C (Tetrahexyldecyl Ascorbate): A deeply penetrating, oil-soluble form of Vitamin C that brightens dark spots, evens skin tone, and boosts collagen production without the irritation or instability of traditional Vitamin C.
- Heparan Sulfate Analog (HSA): Senté's breakthrough patented molecule is clinically proven to go beyond surface hydration to deeply replenish moisture, reduce visible redness, and support the skin's natural ability to repair itself at a cellular level, delivering profound and lasting rejuvenation.
- Terminalia Chebula Fruit Extract: A potent antioxidant derived from one of Ayurveda's most revered botanicals, it neutralizes free radical damage, supports collagen integrity, and helps visibly firm and brighten skin with consistent use.
- Acetyl Glucosamine: A skin-identical sugar molecule that inhibits melanin production at the source, visibly fading dark spots and uneven tone while simultaneously supporting skin hydration and barrier repair.
Water/Aqua/Eau, Tetrahexyldecyl Ascorbate, Ethylhexyl Olivate, Dimethicone/Vinyl Dimethicone Crosspolymer, Glycerin, Acetyl Glucosamine, Polyacrylate-13, Dimethicone, Heparan Sulfate, Terminalia Chebula Fruit Extract, Polyisobutene, Oryza Sativa Bran Extract, Polyacrylate Crosspolymer-6, Tocopheryl Acetate, Helianthus Annuus Extract, C12-14 Alketh-12, Polysorbate 20, Sorbitan Isostearate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Chlorphenesin, Phenoxyethanol, Ethylhexylglycerin, Disodium EDTA
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What makes Sente Defense C Serum different from other vitamin C serums?
Sente Defense C Serum uses THD Ascorbate, a gentle form of vitamin C that is significantly more stable and better tolerated than L-ascorbic acid, which is the most common form used in vitamin C serums. THD Ascorbate does not oxidize as quickly, remains potent throughout the life of the product, and is far less likely to cause stinging or irritation, making it a superior choice for sensitive or reactive skin.
What is HSA and why is it in a vitamin C serum?
HSA stands for Heparan Sulfate Analog, Sente's patented ingredient that mimics the naturally occurring glycosaminoglycan heparan sulfate in skin. HSA supports cellular communication, barrier function, and skin renewal, enhancing how the skin receives and responds to the vitamin C complex in Defense C Serum for stronger overall results.
Can I use Sente Defense C Serum if I have sensitive skin?
Yes, Sente Defense C Serum is well suited for sensitive and reactive skin types. THD Ascorbate is far less irritating than L-ascorbic acid, and the formula is free of the harsh acidic pH environments that make traditional vitamin C serums difficult for sensitive skin to tolerate.
When in my routine should I use Sente Defense C Serum?
Apply Sente Defense C Serum in the morning after cleansing and before moisturizer and SPF. Pairing antioxidant vitamin C with sunscreen creates a synergistic layer of defense against UV and environmental free radical damage that neither product can fully provide alone.
Can I use Sente Defense C Serum with retinol or other actives?
Yes, the THD Ascorbate in Defense C Serum is compatible with most actives including niacinamide, peptides, and hyaluronic acid in the morning routine. If you use retinol in the evening, Sente Defense C Serum in the morning provides a complementary antioxidant step that supports skin repair throughout the day.
How long does it take to see brightening results with Sente Defense C Serum?
Most users begin to notice a more luminous, even complexion within 4 to 6 weeks of consistent daily use. Darker spots and areas of sun damage typically show visible improvement between 8 and 12 weeks, depending on the depth of the discoloration and how consistently SPF is used alongside the serum.
Is Sente Defense C Serum safe to use during and after professional treatments?
Sente Defense C Serum is generally well tolerated alongside professional treatments, but always follow post-care guidelines from your provider before reintroducing any active serum after a chemical peel, laser, or microneedling session. Its gentle, non-acidic formula typically allows for earlier reintroduction than traditional vitamin C serums.
Why buy Sente Defense C Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of Sente Labs, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if this product is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
Senté Defense C Serum is a brightening and antioxidant vitamin C serum built for skin that needs both tone correction and genuine healing support. Powered by Tetrahexyldecyl Ascorbate, a stable oil-soluble form of vitamin C that penetrates more deeply than traditional formulas, alongside Senté's patented Heparan Sulfate Analog, it brightens dark spots, neutralizes daily environmental damage, and supports the skin's natural repair process in a single lightweight step. It works for all skin types, including those who have found conventional vitamin C serums too harsh or too unstable to trust.
Key Benefits
Brightens and Fades Dark Spots
Tetrahexyldecyl Ascorbate penetrates deeply to inhibit melanin production at the source, visibly fading sun damage, post-acne marks, and uneven tone over time.
Heals and Repairs
HSA supports the skin's natural cellular repair cycle, helping to reduce visible redness, calm reactive skin, and restore a healthier, more even-looking complexion alongside the vitamin C.
Antioxidant Defense Every Day
Neutralizes the free radical damage caused by UV exposure, pollution, and environmental stress that accumulates over time and accelerates visible aging.
Supports Collagen Production
Vitamin C is a key cofactor in collagen synthesis, helping to maintain firmness and reduce the appearance of fine lines with consistent daily use.
Stable and Skin-Friendly
Unlike L-ascorbic acid, Tetrahexyldecyl Ascorbate resists oxidation and does not cause the stinging or irritation that makes traditional vitamin C serums difficult to tolerate.
In a clinical 8 week study:
- 94% of subjects showed improvement in skin brightness
- 87% of subjects showed improvement in skin evenness
- 87% of subjects showed improvement in skin luminosity
*Data on file, Sente
Senté Defense C Serum is for anyone dealing with dullness, uneven skin tone, sun damage, or dark spots who wants real brightening results without the irritation that traditional vitamin C serums often bring. Because Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of vitamin C, it suits sensitive, rosacea-prone, and reactive skin types that have struggled with standard ascorbic acid formulas.
Dry skin types especially love this serum for the deeply hydrating, luminous finish it leaves behind, giving skin a healthy, lit-from-within glow rather than the tight or stripped feeling that water-based vitamin C formulas can cause.
It works beautifully as a morning serum layered beneath SPF for daily antioxidant protection, and pairs seamlessly with the rest of the Senté lineup for anyone focused on both brightening and long-term prevention.
Apply Sente Defense C Serum every morning before SPF for maximum antioxidant benefit. Because IAA is stable and non-irritating, you can comfortably layer it with niacinamide, peptides, and even prescription actives without the reactivity that traditional L-ascorbic acid formulas sometimes cause.
Prepare: Apply to clean, dry skin in the morning after cleansing and toning.
Apply: Dispense 3 to 5 drops into your palm or fingertips and gently press the serum into the face, neck, and upper chest.
Technique: Pat gently rather than rubbing to preserve the serum's integrity and encourage even absorption. Allow 30 to 60 seconds to absorb before applying the next step.
Frequency: Use every morning as part of your AM routine. Follow with a moisturizer and a broad-spectrum SPF of 30 or higher to maximize antioxidant protection throughout the day.
- Vitamin C (Tetrahexyldecyl Ascorbate): A deeply penetrating, oil-soluble form of Vitamin C that brightens dark spots, evens skin tone, and boosts collagen production without the irritation or instability of traditional Vitamin C.
- Heparan Sulfate Analog (HSA): Senté's breakthrough patented molecule is clinically proven to go beyond surface hydration to deeply replenish moisture, reduce visible redness, and support the skin's natural ability to repair itself at a cellular level, delivering profound and lasting rejuvenation.
- Terminalia Chebula Fruit Extract: A potent antioxidant derived from one of Ayurveda's most revered botanicals, it neutralizes free radical damage, supports collagen integrity, and helps visibly firm and brighten skin with consistent use.
- Acetyl Glucosamine: A skin-identical sugar molecule that inhibits melanin production at the source, visibly fading dark spots and uneven tone while simultaneously supporting skin hydration and barrier repair.
Water/Aqua/Eau, Tetrahexyldecyl Ascorbate, Ethylhexyl Olivate, Dimethicone/Vinyl Dimethicone Crosspolymer, Glycerin, Acetyl Glucosamine, Polyacrylate-13, Dimethicone, Heparan Sulfate, Terminalia Chebula Fruit Extract, Polyisobutene, Oryza Sativa Bran Extract, Polyacrylate Crosspolymer-6, Tocopheryl Acetate, Helianthus Annuus Extract, C12-14 Alketh-12, Polysorbate 20, Sorbitan Isostearate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Chlorphenesin, Phenoxyethanol, Ethylhexylglycerin, Disodium EDTA
What makes Sente Defense C Serum different from other vitamin C serums?
Sente Defense C Serum uses THD Ascorbate, a gentle form of vitamin C that is significantly more stable and better tolerated than L-ascorbic acid, which is the most common form used in vitamin C serums. THD Ascorbate does not oxidize as quickly, remains potent throughout the life of the product, and is far less likely to cause stinging or irritation, making it a superior choice for sensitive or reactive skin.
What is HSA and why is it in a vitamin C serum?
HSA stands for Heparan Sulfate Analog, Sente's patented ingredient that mimics the naturally occurring glycosaminoglycan heparan sulfate in skin. HSA supports cellular communication, barrier function, and skin renewal, enhancing how the skin receives and responds to the vitamin C complex in Defense C Serum for stronger overall results.
Can I use Sente Defense C Serum if I have sensitive skin?
Yes, Sente Defense C Serum is well suited for sensitive and reactive skin types. THD Ascorbate is far less irritating than L-ascorbic acid, and the formula is free of the harsh acidic pH environments that make traditional vitamin C serums difficult for sensitive skin to tolerate.
When in my routine should I use Sente Defense C Serum?
Apply Sente Defense C Serum in the morning after cleansing and before moisturizer and SPF. Pairing antioxidant vitamin C with sunscreen creates a synergistic layer of defense against UV and environmental free radical damage that neither product can fully provide alone.
Can I use Sente Defense C Serum with retinol or other actives?
Yes, the THD Ascorbate in Defense C Serum is compatible with most actives including niacinamide, peptides, and hyaluronic acid in the morning routine. If you use retinol in the evening, Sente Defense C Serum in the morning provides a complementary antioxidant step that supports skin repair throughout the day.
How long does it take to see brightening results with Sente Defense C Serum?
Most users begin to notice a more luminous, even complexion within 4 to 6 weeks of consistent daily use. Darker spots and areas of sun damage typically show visible improvement between 8 and 12 weeks, depending on the depth of the discoloration and how consistently SPF is used alongside the serum.
Is Sente Defense C Serum safe to use during and after professional treatments?
Sente Defense C Serum is generally well tolerated alongside professional treatments, but always follow post-care guidelines from your provider before reintroducing any active serum after a chemical peel, laser, or microneedling session. Its gentle, non-acidic formula typically allows for earlier reintroduction than traditional vitamin C serums.
Why buy Sente Defense C Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of Sente Labs, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if this product is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
