Circadia Nighttime Repair is a restorative night cream from Circadia by Dr. Pugliese, formulated to support visible skin renewal while you sleep through a carefully balanced blend of vitamin A, peptides, ceramides, and antioxidant botanicals. It is designed for those who want the benefits of a retinoid without the irritation that can come with higher-strength formulas, making it a well-tolerated entry point into vitamin A therapy. The cream carries a subtle, warm vanilla note from vanilla planifolia fruit extract.

Key Benefits

Supports cell turnover without irritation Retinyl acetate delivers a gentle, well-tolerated form of vitamin A that encourages skin to renew itself overnight, helping to smooth texture and refine uneven tone with continued use.

Firms skin and softens the look of fine lines Palmitoyl tripeptide-38 and palmitoyl tetrapeptide-7 work together to stimulate collagen and reduce the visible depth of fine lines, helping skin feel firmer over time.

Reinforces the skin barrier A trio of ceramides, ceramide NP, ceramide AP, and ceramide EOP, combined with cholesterol and phytosphingosine, mirrors the skin's own lipid matrix to strengthen the barrier, reduce moisture loss, and support a more resilient surface.

Calms redness and visibly evens skin tone Niacinamide, along with asiaticoside, asiatic acid, and madecassic acid from centella asiatica, work to calm inflammation, reduce redness, and support a more even, consistent complexion.

Delivers antioxidant protection overnight Ergothioneine, tetrahexyldecyl ascorbate, tocopherol, and rosmarinus officinalis leaf extract neutralize free radicals and help protect skin from the oxidative stress that accelerates visible aging.

If you have been curious about adding vitamin A to your routine but have felt hesitant about dryness, flaking, or sensitivity, Circadia Nighttime Repair is built for exactly that starting point. It is particularly well-suited to sensitive, dry, or barrier-compromised skin that needs the support of ceramides and calming botanicals alongside a retinoid.

This night cream also works well for those in their 20s and 30s who want to get ahead of early fine lines and uneven texture, as well as anyone who has taken a break from stronger retinoids and wants to reintroduce vitamin A gradually.

If you are managing redness or post-breakout marks alongside early signs of aging, the combination of niacinamide and centella actives makes this a particularly useful option for nighttime use.

If applying Circadia Nighttime Repair to completely dry skin causes any sensitivity, try the buffering method: apply it over a thin layer of your moisturizer instead. This slows absorption slightly, which can make the retinoid phase-in period more comfortable without reducing your long-term results.

Prepare: Start with clean, dry skin in the evening.

Apply: Dispense a small amount and smooth evenly over the face, avoiding the eye area.

Frequency: Begin with 2 to 3 nights per week and gradually increase as your skin adjusts. Follow with a moisturizer if needed.

Daytime: Apply broad-spectrum sunscreen every morning when using any vitamin A formula.