Circadia Serum 71
Circadia Serum 71 is a multitasking pigment-correcting and firming serum formulated with 2% tranexamic acid, 5% mandelic acid, and 0.3% azelaic acid to visibly fade dark spots, smooth texture, reduce breakouts, and calm redness — without triggering irritation in sensitive skin.
Unlike traditional brightening serums that focus only on exfoliation, Serum 71 also includes Neodermyl®, a next-generation copper peptide clinically known to stimulate collagen and elastin production, improving skin density and elasticity while maintaining barrier stability.
Circadia Serum 71 is a multitasking pigment-correcting and firming serum formulated with 2% tranexamic acid, 5% mandelic acid, and 0.3% azelaic acid to fade dark spots, smooth texture, reduce breakouts, and calm redness — without irritating sensitive skin.
Unlike traditional brightening treatments that rely on aggressive exfoliation, Serum 71 pairs targeted acids with Neodermyl®, a next-generation copper peptide that supports collagen and elastin production for improved firmness and density. CM-Glucan Forte helps calm inflammation and strengthen the skin barrier, making this formula safe for sensitive, acne-prone, and mature skin.
- 2% Tranexamic Acid for melasma and dark spot correction
- 5% Mandelic Acid for gentle exfoliation and pore refinement
- 0.3% Azelaic Acid for redness and acne control
- Neodermyl® Copper Peptide for firming support
- CM-Glucan Forte to calm and reinforce the barrier
Key Benefits
- Fades Hyperpigmentation & Melasma: Tranexamic acid interrupts excess pigment signaling
- Clears Post-Acne Marks (PIH): Mandelic + Azelaic acids refine and brighten
- Improves Firmness & Elasticity: Neodermyl® stimulates collagen and elastin
- Calms Redness & Inflammation: CM-Glucan Forte supports barrier recovery
- Controls Breakouts: Gentle antibacterial acids keep pores clear
- Refines Texture Without Peeling: Smooths skin without visible flaking or downtime
- Circadia Serum 71 is suitable for all skin types, including sensitive, oily, and mature skin. Its non-inflammatory formula delivers visible brightening and firming benefits without the "purge" or redness caused by traditional peels, making it a safe option for delicate complexions.
- This serum is especially beneficial for anyone concerned with "adult acne," melasma, post-inflammatory hyperpigmentation (PIH), or a loss of firmness. By combining acne-fighting acids with anti-aging peptides, it allows you to treat multiple concerns with a single product. It is an excellent choice for maintaining results between professional chemical peels or enzyme treatments.
For best results, use Circadia Serum 71 as your primary evening treatment to target hyperpigmentation, melasma, adult acne, and early loss of firmness. Its combination of tranexamic acid, mandelic acid, and azelaic acid works overnight to fade dark spots, refine texture, and calm inflammation while supporting collagen production.
For Enhanced Brightening Results:
For a more intensive brightening routine, layer Serum 71 over Licorice & Bearberry Brightening Mist. The botanical brighteners in the mist work synergistically with the acids in Serum 71 to interrupt pigment formation at multiple levels, accelerating the fading of stubborn dark spots and post-inflammatory hyperpigmentation (PIH).
For Breakouts + Fine Lines (All-in-One Treatment):
If you are managing both adult acne and visible signs of aging, Serum 71 functions as an effective all-in-one evening solution — clearing pores while stimulating collagen and elastin for firmer skin.
For Extra Hydration & Barrier Support:
If your skin feels dry or reactive, layer Serum 71 under AquaPorin Hydrating Cream to reduce transepidal water loss (TEWL) and maintain barrier stability.
For enhanced anti-aging results, follow with Nighttime Repair to wake up with smoother, firmer, and visibly clearer skin.
- Cleanse and lightly mist skin.
- Apply 3–5 drops in the evening.
- Press gently into face, neck, and chest.
- Follow with moisturizer.
- Always apply SPF the next morning.
Recommended Adjustment Period:
- Weeks 1–2: Use 3x weekly
Week 3+: Increase to nightly as tolerated
- Tranexamic Acid: Derived from an essential amino acid, this mega-brightening ingredient possesses potent anti-inflammatory properties and inhibits pigment formation while fading current dark spots as well.
- Mandelic Acid: An alpha-hydroxy acid that brightens, suppresses hyperpigmentation, and enhances cell turnover.
- Azelaic Acid: Gently clears pores of bacteria while diminishing hyperpigmentation by reducing melanin production and calming inflammation.
- Neodermyl®: A copper-based peptide that accelerates wound healing and cell regeneration while stimulating collagen and elastin for firming benefits.
- CM-Glucan Forte: A stabilized form of beta-glucan that rebalances the skin's immune system, soothes irritation, and strengthens the skin barrier.
Aqua/Water, Propanediol, Mandelic Acid, Butylene Glycol, Tranexamic Acid, Phenoxyethanol, Sodium PCA, Hydroxyethylcellulose, Sodium Hydroxide, Azelaic Acid, Glycerin, Magnesium Carboxymethyl Beta-Glucan, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Alcohol, Sodium Hydroxide.
What does Circadia Serum 71 treat?
Circadia Serum 71 treats hyperpigmentation, melasma, post-acne dark spots (PIH), adult acne, redness, uneven texture, and early signs of skin laxity in one formula.
Is Circadia Serum 71 good for melasma?
Yes. The 2% tranexamic acid helps interrupt pigment signaling pathways responsible for melasma and stubborn dark patches, making it an effective non-hydroquinone option.
Is Circadia Serum 71 acne-safe?
Yes. The mandelic and azelaic acids help keep pores clear and reduce inflammation, making it suitable for acne-prone and adult acne skin types.
Does Circadia Serum 71 cause peeling?
No. This serum exfoliates gently at a cellular level. Most users experience smoother texture and glow without visible peeling or downtime.
Can Circadia Serum 71 be used with Retinol?
To prevent over-exfoliation, alternate nights. Use Serum 71 one evening and Retinol the next.
Is Circadia Serum 71 safe for sensitive skin?
Yes. The formula includes CM-Glucan Forte to calm irritation and strengthen the skin barrier, making it more tolerable than traditional acid treatments.
How long does it take to see results from Circadia Serum 71?
Brightness and smoother texture may appear within 1–2 weeks. Fading of deeper pigmentation and visible firming typically take 4–8 weeks of consistent use.
Does Circadia Serum 71 help with redness?
Yes. Azelaic acid and CM-Glucan Forte help calm inflammation and reduce visible redness while improving overall tone.
Can I use Circadia Serum 71 every night?
Yes, after an adjustment period. Begin 3 times per week and increase to nightly use as tolerated.
Is Circadia Serum 71 better than a traditional chemical peel?
Serum 71 provides gradual pigment correction and collagen support without downtime. It is ideal for maintenance between professional treatments.
A multitasking Tranexamic, Mandelic & Azelaic Acid serum for hyperpigmentation, adult acne, and loss of firmness — brightening, calming, and firming in one advanced treatment step.
- Unit price
- /per
Primary Concerns:
- Acne
- Dullness
- Loss of Firmness
- Pigmentation
Best For:
- Dry
- Sensitive
- Combination
- Normal
- Oily
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Circadia Serum 71
Circadia Serum 71 is a multitasking pigment-correcting and firming serum formulated with 2% tranexamic acid, 5% mandelic acid, and 0.3% azelaic acid to visibly fade dark spots, smooth texture, reduce breakouts, and calm redness — without triggering irritation in sensitive skin.
Unlike traditional brightening serums that focus only on exfoliation, Serum 71 also includes Neodermyl®, a next-generation copper peptide clinically known to stimulate collagen and elastin production, improving skin density and elasticity while maintaining barrier stability.
Circadia Serum 71 is a multitasking pigment-correcting and firming serum formulated with 2% tranexamic acid, 5% mandelic acid, and 0.3% azelaic acid to fade dark spots, smooth texture, reduce breakouts, and calm redness — without irritating sensitive skin.
Unlike traditional brightening treatments that rely on aggressive exfoliation, Serum 71 pairs targeted acids with Neodermyl®, a next-generation copper peptide that supports collagen and elastin production for improved firmness and density. CM-Glucan Forte helps calm inflammation and strengthen the skin barrier, making this formula safe for sensitive, acne-prone, and mature skin.
- 2% Tranexamic Acid for melasma and dark spot correction
- 5% Mandelic Acid for gentle exfoliation and pore refinement
- 0.3% Azelaic Acid for redness and acne control
- Neodermyl® Copper Peptide for firming support
- CM-Glucan Forte to calm and reinforce the barrier
Key Benefits
- Fades Hyperpigmentation & Melasma: Tranexamic acid interrupts excess pigment signaling
- Clears Post-Acne Marks (PIH): Mandelic + Azelaic acids refine and brighten
- Improves Firmness & Elasticity: Neodermyl® stimulates collagen and elastin
- Calms Redness & Inflammation: CM-Glucan Forte supports barrier recovery
- Controls Breakouts: Gentle antibacterial acids keep pores clear
- Refines Texture Without Peeling: Smooths skin without visible flaking or downtime
- Circadia Serum 71 is suitable for all skin types, including sensitive, oily, and mature skin. Its non-inflammatory formula delivers visible brightening and firming benefits without the "purge" or redness caused by traditional peels, making it a safe option for delicate complexions.
- This serum is especially beneficial for anyone concerned with "adult acne," melasma, post-inflammatory hyperpigmentation (PIH), or a loss of firmness. By combining acne-fighting acids with anti-aging peptides, it allows you to treat multiple concerns with a single product. It is an excellent choice for maintaining results between professional chemical peels or enzyme treatments.
For best results, use Circadia Serum 71 as your primary evening treatment to target hyperpigmentation, melasma, adult acne, and early loss of firmness. Its combination of tranexamic acid, mandelic acid, and azelaic acid works overnight to fade dark spots, refine texture, and calm inflammation while supporting collagen production.
For Enhanced Brightening Results:
For a more intensive brightening routine, layer Serum 71 over Licorice & Bearberry Brightening Mist. The botanical brighteners in the mist work synergistically with the acids in Serum 71 to interrupt pigment formation at multiple levels, accelerating the fading of stubborn dark spots and post-inflammatory hyperpigmentation (PIH).
For Breakouts + Fine Lines (All-in-One Treatment):
If you are managing both adult acne and visible signs of aging, Serum 71 functions as an effective all-in-one evening solution — clearing pores while stimulating collagen and elastin for firmer skin.
For Extra Hydration & Barrier Support:
If your skin feels dry or reactive, layer Serum 71 under AquaPorin Hydrating Cream to reduce transepidal water loss (TEWL) and maintain barrier stability.
For enhanced anti-aging results, follow with Nighttime Repair to wake up with smoother, firmer, and visibly clearer skin.
- Cleanse and lightly mist skin.
- Apply 3–5 drops in the evening.
- Press gently into face, neck, and chest.
- Follow with moisturizer.
- Always apply SPF the next morning.
Recommended Adjustment Period:
- Weeks 1–2: Use 3x weekly
Week 3+: Increase to nightly as tolerated
- Tranexamic Acid: Derived from an essential amino acid, this mega-brightening ingredient possesses potent anti-inflammatory properties and inhibits pigment formation while fading current dark spots as well.
- Mandelic Acid: An alpha-hydroxy acid that brightens, suppresses hyperpigmentation, and enhances cell turnover.
- Azelaic Acid: Gently clears pores of bacteria while diminishing hyperpigmentation by reducing melanin production and calming inflammation.
- Neodermyl®: A copper-based peptide that accelerates wound healing and cell regeneration while stimulating collagen and elastin for firming benefits.
- CM-Glucan Forte: A stabilized form of beta-glucan that rebalances the skin's immune system, soothes irritation, and strengthens the skin barrier.
Aqua/Water, Propanediol, Mandelic Acid, Butylene Glycol, Tranexamic Acid, Phenoxyethanol, Sodium PCA, Hydroxyethylcellulose, Sodium Hydroxide, Azelaic Acid, Glycerin, Magnesium Carboxymethyl Beta-Glucan, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Alcohol, Sodium Hydroxide.
What does Circadia Serum 71 treat?
Circadia Serum 71 treats hyperpigmentation, melasma, post-acne dark spots (PIH), adult acne, redness, uneven texture, and early signs of skin laxity in one formula.
Is Circadia Serum 71 good for melasma?
Yes. The 2% tranexamic acid helps interrupt pigment signaling pathways responsible for melasma and stubborn dark patches, making it an effective non-hydroquinone option.
Is Circadia Serum 71 acne-safe?
Yes. The mandelic and azelaic acids help keep pores clear and reduce inflammation, making it suitable for acne-prone and adult acne skin types.
Does Circadia Serum 71 cause peeling?
No. This serum exfoliates gently at a cellular level. Most users experience smoother texture and glow without visible peeling or downtime.
Can Circadia Serum 71 be used with Retinol?
To prevent over-exfoliation, alternate nights. Use Serum 71 one evening and Retinol the next.
Is Circadia Serum 71 safe for sensitive skin?
Yes. The formula includes CM-Glucan Forte to calm irritation and strengthen the skin barrier, making it more tolerable than traditional acid treatments.
How long does it take to see results from Circadia Serum 71?
Brightness and smoother texture may appear within 1–2 weeks. Fading of deeper pigmentation and visible firming typically take 4–8 weeks of consistent use.
Does Circadia Serum 71 help with redness?
Yes. Azelaic acid and CM-Glucan Forte help calm inflammation and reduce visible redness while improving overall tone.
Can I use Circadia Serum 71 every night?
Yes, after an adjustment period. Begin 3 times per week and increase to nightly use as tolerated.
Is Circadia Serum 71 better than a traditional chemical peel?
Serum 71 provides gradual pigment correction and collagen support without downtime. It is ideal for maintenance between professional treatments.
Explore More Recommendations
Circadia Serum 71
- JCJasmine C.Verified BuyerReviewingCircadia Serum 71I recommend this productHow old are you? 18-29What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Acne, Ageing, Blemish-prone, Pigmentation, RednessRated 5 out of 5 stars6 minutes agoAlways on my reorder list
Great serum! Minimizes pores and helps with acne scars.
Was this helpful? - LJLaura J.Verified BuyerReviewingCircadia Serum 71I recommend this productHow old are you? 40-49What is your skin type? OilyWhat is your skin tone? MediumWhat are your skin concerns? Sun Damage, Wrinkles, Pigmentation, Ageing, OilinessRated 5 out of 5 stars1 month agoEffective
I’ve been using this serum for several months now. I’ve seen a dramatic improvement in my skins appearance and texture. A little bit goes a long ways. Use sparingly because it’s expensive, but worth it.
Was this helpful? - MDMariah D.Verified BuyerReviewingCircadia Serum 71I recommend this productHow old are you? 30-39What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Acne, Ageing, Pigmentation, Wrinkles, SensitivityRated 5 out of 5 stars1 month agoNice serum
I got this to alternate with my mandelic serum and I like it so far. I've noticed a few small breakouts which could be purging from some bumps under the skin. Not sure if it's this serum causing it but I'll keep using it and see how it goes.
Was this helpful? - CSChristine S.Verified BuyerReviewingCircadia Serum 71I recommend this productHow old are you? 40-49What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Ageing, SensitivityRated 5 out of 5 stars2 months agoFirming!
I have noticed my skin improve in texture and firmness. Love!
Was this helpful? - DBDomanique B.Verified BuyerReviewingCircadia Serum 71I recommend this productHow old are you? 40-49What is your skin type? CombinationWhat is your skin tone? TanWhat are your skin concerns? Pigmentation, Sun Damage, AcneRated 5 out of 5 stars5 months agoGreat product
I noticed a difference in 2 weeks as well as my aesthetician. I will definitely be purchasing again.
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