Colorescience Barrier Pro Serum Spray
The first serum spray to activate Vitamin D and balance your microbiome for radiant, resilient skin.
Colorescience’s Barrier Pro™ Serum Spray is a lightweight, fine mist that goes beyond hydration - delivering cutting-edge skin health benefits with every spritz. Powered by exclusive adapDvate™ Technology, it mimics the positive effects of sunlight to support your skin’s natural ability to produce Vitamin D, without UV exposure or damage. Combined with pre-, pro-, and postbiotic actives, this serum spray strengthens your skin barrier, balances the microbiome, and boosts hydration for smoother, firmer, more luminous skin.
Why You'll Love It:
- Exclusive adapDvate™ Technology promotes Vitamin D production without UV exposure
- Pre-, pro-, and postbiotics balance and fortify the microbiome
- Multi-layer hydration with tri-molecular hyaluronic acid
- Advanced antioxidants neutralize free radicals
- Immediately soothes, hydrates, and brightens stressed skin
- Lightweight, oil-free, vegan, fragrance-free, and non-comedogenic
In just 4 weeks in a clinical study:
- 97% saw improved skin tone & reduced blotchiness
- 90% noticed a boost in radiance & luminosity
- 87% reported smoother texture & fewer visible lines
Unlike oral Vitamin D supplements, Barrier Pro™ Serum Spray works directly at the skin level, where Vitamin D receptors reside. By mimicking the effects of the sun within the skin, it ensures your complexion gets localized Vitamin D support, something supplements alone can’t provide.
AM + PM: Shake well, close eyes, and spritz 3–5 pumps across face, neck, and chest. Allow to dry, then follow with serums, sunscreen, and makeup.
Throughout the Day: Reapply as needed to refresh hydration and boost skin resilience. Pro tip: use before reapplying Colorescience® Total Protection® Brush-On Shield SPF 50 for an even smoother finish.
May also be applied to hands and body to strengthen and protect skin exposed to stressors.
- Lithops Plant Cell Nectar: Called the “Living Stone,” this resilient desert succulent survives intense sunlight by mastering light and water management. It helps skin mimic that same brilliance, boosting hydration reserves and activating Vitamin D without UV exposure.
- Multi-Weight Hyaluronic Acid: A blend of hyaluronic acid molecules in varying sizes that hydrate multiple layers of the skin at once. This complex draws in lasting moisture, plumps the appearance of fine lines, and helps maintain a soft, supple, well cushioned complexion.
- Chronopeptide: A powerful amino acid–based peptide that works with your skin’s natural rhythm, enhancing Vitamin D conversion to support renewal, repair, and nutrient delivery day and night.
- Prickly Pear Cactus Extract: Antioxidant-rich, hydrating ingredient that supports the skin’s NMF (natural moisturizing factor), smooths the skin, and strengthens the barrier.
- Goji Berry Extract: Powerful antioxidant that provides phytonutrients, vitamins, and trace minerals, along with acting as a prebiotic to support healthy bacteria.
- Lactobacillus Ferment: Supports a healthy skin microbiome, calms inflammation, and strengthens the barrier—ideal for sensitive or post-procedure skin.
- Squalane: Keeps skin hydrated and balances oil production by mimicking the skin’s acid mantle while also reducing inflammation, soothing skin irritation, and improving elasticity.
- Hydrolyzed Pea Protein: Contains a complete amino acid profile to help repair and regenerate the skin and boosts barrier protection from environmental damage.
Aqua/Water/Eau, Glycerin, Polyglyceryl-10 Oleate, Squalane, Lactobacillus Ferment, Sodium Hydroxide, Propanediol, Fructooligosaccharides, Glycoproteins, Bioflavonoids, Lycium Barbarum (Goji) Fruit Extract, Pentylene Glycol, Opuntia Ficus-Indica Stem Extract, Ethylhexylglycerin, Calcium Gluconate, Gluconolactone, Sodium Hyaluronate, Glutamylamidoethyl Imidazole, Cyamopsis Tetragonoloba (Guar) Gum, Xanthan Gum, Glucose, Hydrolyzed Pea Protein, Phytic Acid, Sodium Chloride, Tocopherol, Phenoxyethanol, Sodium Benzoate, Sodium Succinate
*This formula does not contain the active form of Vitamin D (calcitriol)
A vitamin D activating serum spray with microbiome and antioxidant support to hydrate, strengthen, and protect skin for lasting radiance and resilience.
- Unit price
- /per
Primary Concerns:
- Redness/Rosacea
- Fine Lines
- Compromised Barrier
Best For:
- Dry
- Normal
- Oily
- Combination
- Sensitive
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Colorescience Barrier Pro Serum Spray
The first serum spray to activate Vitamin D and balance your microbiome for radiant, resilient skin.
Colorescience’s Barrier Pro™ Serum Spray is a lightweight, fine mist that goes beyond hydration - delivering cutting-edge skin health benefits with every spritz. Powered by exclusive adapDvate™ Technology, it mimics the positive effects of sunlight to support your skin’s natural ability to produce Vitamin D, without UV exposure or damage. Combined with pre-, pro-, and postbiotic actives, this serum spray strengthens your skin barrier, balances the microbiome, and boosts hydration for smoother, firmer, more luminous skin.
Why You'll Love It:
- Exclusive adapDvate™ Technology promotes Vitamin D production without UV exposure
- Pre-, pro-, and postbiotics balance and fortify the microbiome
- Multi-layer hydration with tri-molecular hyaluronic acid
- Advanced antioxidants neutralize free radicals
- Immediately soothes, hydrates, and brightens stressed skin
- Lightweight, oil-free, vegan, fragrance-free, and non-comedogenic
In just 4 weeks in a clinical study:
- 97% saw improved skin tone & reduced blotchiness
- 90% noticed a boost in radiance & luminosity
- 87% reported smoother texture & fewer visible lines
Unlike oral Vitamin D supplements, Barrier Pro™ Serum Spray works directly at the skin level, where Vitamin D receptors reside. By mimicking the effects of the sun within the skin, it ensures your complexion gets localized Vitamin D support, something supplements alone can’t provide.
AM + PM: Shake well, close eyes, and spritz 3–5 pumps across face, neck, and chest. Allow to dry, then follow with serums, sunscreen, and makeup.
Throughout the Day: Reapply as needed to refresh hydration and boost skin resilience. Pro tip: use before reapplying Colorescience® Total Protection® Brush-On Shield SPF 50 for an even smoother finish.
May also be applied to hands and body to strengthen and protect skin exposed to stressors.
- Lithops Plant Cell Nectar: Called the “Living Stone,” this resilient desert succulent survives intense sunlight by mastering light and water management. It helps skin mimic that same brilliance, boosting hydration reserves and activating Vitamin D without UV exposure.
- Multi-Weight Hyaluronic Acid: A blend of hyaluronic acid molecules in varying sizes that hydrate multiple layers of the skin at once. This complex draws in lasting moisture, plumps the appearance of fine lines, and helps maintain a soft, supple, well cushioned complexion.
- Chronopeptide: A powerful amino acid–based peptide that works with your skin’s natural rhythm, enhancing Vitamin D conversion to support renewal, repair, and nutrient delivery day and night.
- Prickly Pear Cactus Extract: Antioxidant-rich, hydrating ingredient that supports the skin’s NMF (natural moisturizing factor), smooths the skin, and strengthens the barrier.
- Goji Berry Extract: Powerful antioxidant that provides phytonutrients, vitamins, and trace minerals, along with acting as a prebiotic to support healthy bacteria.
- Lactobacillus Ferment: Supports a healthy skin microbiome, calms inflammation, and strengthens the barrier—ideal for sensitive or post-procedure skin.
- Squalane: Keeps skin hydrated and balances oil production by mimicking the skin’s acid mantle while also reducing inflammation, soothing skin irritation, and improving elasticity.
- Hydrolyzed Pea Protein: Contains a complete amino acid profile to help repair and regenerate the skin and boosts barrier protection from environmental damage.
Aqua/Water/Eau, Glycerin, Polyglyceryl-10 Oleate, Squalane, Lactobacillus Ferment, Sodium Hydroxide, Propanediol, Fructooligosaccharides, Glycoproteins, Bioflavonoids, Lycium Barbarum (Goji) Fruit Extract, Pentylene Glycol, Opuntia Ficus-Indica Stem Extract, Ethylhexylglycerin, Calcium Gluconate, Gluconolactone, Sodium Hyaluronate, Glutamylamidoethyl Imidazole, Cyamopsis Tetragonoloba (Guar) Gum, Xanthan Gum, Glucose, Hydrolyzed Pea Protein, Phytic Acid, Sodium Chloride, Tocopherol, Phenoxyethanol, Sodium Benzoate, Sodium Succinate
*This formula does not contain the active form of Vitamin D (calcitriol)
Explore More Recommendations
Colorescience Barrier Pro Serum Spray
- HVHannah V.Verified BuyerReviewingColorescience Barrier Pro Serum SprayI recommend this productHow old are you? 30-39What is your skin type? CombinationWhat is your skin tone? FairWhat are your skin concerns? Acne, Ageing, Sensitivity, Wrinkles, RednessRated 4 out of 5 stars5 days agoVery good
I love the mist but have not seen much change
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