FREE U.S. SHIPPING ON ORDERS $49+

iS Clinical C Eye Serum Advance+

iS Clinical C Eye Serum Advance+ is a targeted, clinical-strength eye serum that brings together pure ascorbic acid, sodium hyaluronate, and tripeptide-1 to visibly reduce fine lines, dark circles, and puffiness while defending the delicate eye area against environmental damage. iS Clinical is known for formulating with pharmaceutical-grade actives, and this serum reflects that commitment with a clean, lightweight base that absorbs quickly and layers seamlessly under makeup. It is fragrance-free, making it a comfortable daily option even for those with reactive skin.

Key Benefits

Brightens dark circles and evens tone Ascorbic acid, the purest and most potent form of vitamin C, targets discoloration beneath the eyes and works to create a more uniform, rested appearance over time.

Reduces puffiness and soothes the under-eye area Zinc sulfate helps decongest and calm the under-eye area, while polyporus umbellatus (mushroom) extract provides visible soothing support to tired, stressed skin.

Smooths fine lines and supports firmness Sodium hyaluronate draws moisture into the skin to plump the appearance of fine lines, and tripeptide-1 helps reinforce the skin's natural support structure for longer-term resilience.

Delivers meaningful antioxidant protection Ascorbic acid paired with bioflavonoids works to neutralize free radicals generated by UV exposure and daily environmental stress, helping slow the visible signs of premature aging around the eyes.

Hydrates without heaviness or migration Sodium hyaluronate delivers weightless, deep hydration that sits comfortably on the delicate eye area without migrating onto the eyelid or contributing to puffiness.

Acne Safe

iS Clinical C Eye Serum Advance+

Vitamin C eye serum that visibly reduces dark circles, puffiness, and fine lines while delivering antioxidant protection to the delicate eye area.
4.4
Rated 4.4 out of 5 stars
17 Reviews
Regular price $75.00
Unit price
per 
Earn points for this product!
Shipping calculated at checkout.
serum bottle icon

Primary Concerns:

  • Under Eye Circles
  • Fine Lines
  • Pigmentation
  • Sun Damage
Lotion bottle icons

Best For:

  • Combination
  • Dry
  • Normal
  • Oily
  • Sensitive

iS Clinical C Eye Serum Advance+

iS Clinical C Eye Serum Advance+ is a targeted, clinical-strength eye serum that brings together pure ascorbic acid, sodium hyaluronate, and tripeptide-1 to visibly reduce fine lines, dark circles, and puffiness while defending the delicate eye area against environmental damage. iS Clinical is known for formulating with pharmaceutical-grade actives, and this serum reflects that commitment with a clean, lightweight base that absorbs quickly and layers seamlessly under makeup. It is fragrance-free, making it a comfortable daily option even for those with reactive skin.

Key Benefits

Brightens dark circles and evens tone Ascorbic acid, the purest and most potent form of vitamin C, targets discoloration beneath the eyes and works to create a more uniform, rested appearance over time.

Reduces puffiness and soothes the under-eye area Zinc sulfate helps decongest and calm the under-eye area, while polyporus umbellatus (mushroom) extract provides visible soothing support to tired, stressed skin.

Smooths fine lines and supports firmness Sodium hyaluronate draws moisture into the skin to plump the appearance of fine lines, and tripeptide-1 helps reinforce the skin's natural support structure for longer-term resilience.

Delivers meaningful antioxidant protection Ascorbic acid paired with bioflavonoids works to neutralize free radicals generated by UV exposure and daily environmental stress, helping slow the visible signs of premature aging around the eyes.

Hydrates without heaviness or migration Sodium hyaluronate delivers weightless, deep hydration that sits comfortably on the delicate eye area without migrating onto the eyelid or contributing to puffiness.

iS Clinical C Eye Serum Advance+

4.4
Rated 4.4 out of 5 stars
Based on 17 reviews
Total 5 star reviews: 11 Total 4 star reviews: 3 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 1
17 reviews
  • SB
    Shelley B.
    Verified Buyer
    Reviewing
    iS Clinical C Eye Serum Advance+
    I recommend this product
    How old are you? 50-65
    What is your skin type? Normal
    What is your skin tone? Medium
    What are your skin concerns? Ageing
    Rated 5 out of 5 stars
    2 months ago
    IS Clinical C Eye Serum Advance

    This is my favorite eye serum

  • WK
    Wanda K.
    Verified Buyer
    Reviewing
    iS Clinical C Eye Serum Advance+
    I do not recommend this product
    How old are you? 50-65
    What is your skin type? Oily
    What is your skin tone? Medium
    What are your skin concerns? Blemish-prone, Pigmentation, Ageing, Sun Damage
    Rated 1 out of 5 stars
    11 months ago
    Not moisturizing

    I love iS Clinical products but this one didn’t work for me. My eye area has become very dry and my intention was to layer this under an eye cream for extra moisture but that didn’t happen. It made my eyes feel dry.

    AO Profile picture for Art of Skin Care
    Art of Skin Care
    11 months ago

    Hi Wanda! Thanks so much for sharing your experience! I’m sorry to hear this serum didn’t work out the way you hoped. It’s designed to brighten and soften but doesn’t add enough hydration for dryer skin types, so we always recommend layering a good eye cream over it to keep your eye area feeling comfortable.

    If you’d like, our team would be happy to help you find the right combo to tackle dryness and brighten up your eyes. Just let us know—we’re here for you!

  • KH
    Karla H.
    Verified Buyer
    Reviewing
    iS Clinical C Eye Serum Advance+
    I recommend this product
    How old are you? 18-29
    What is your skin type? Dry
    What is your skin tone? Medium
    What are your skin concerns? Blemish-prone, Acne, Ageing, Pigmentation, Sensitivity
    Rated 5 out of 5 stars
    11 months ago
    Miracle serum

    I’m in love a little goes a long way and helps quick

  • AS
    Allison S.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical C Eye Serum Advance+
    I recommend this product
    Rated 5 out of 5 stars
    1 year ago
    iS Clinical C Eye Serum Advance+

    2nd time buying. Lasts a

    2nd time buying. Lasts a really long time. Brand is great.

  • JC
    Julie C.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical C Eye Serum Advance+
    How old are you? 40-49
    Rated 3 out of 5 stars
    1 year ago
    iS Clinical C Eye Serum Advance+

    Not my favorite

    I love the ingredients in this serum and it feels nourishing to my eye areas, but I haven't really seen any results. I had to get used to using the dropper as the liquid comes out really fast. I would not purchase again but I did enjoy trying it