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iS Clinical Hydra-Cool Serum

The iS Clinical Hydra-Cool Serum is a lightweight, fast-absorbing serum designed to deliver immediate hydration, visible calming of redness, and long-term moisture barrier repair for sensitive, reactive, or post-procedure skin. It features a noticeable cooling sensation from menthol that provides instant relief on contact, making it one of the few hydrating serums that addresses both acute skin discomfort and the underlying causes of barrier compromise. The formula is fragrance-free aside from the functional menthol and free of parabens.

Key Benefits

Immediate, deep hydration Sodium hyaluronate draws moisture into the skin and binds up to 1,000 times its weight in water, quickly relieving tightness and dehydration while plumping the look of the skin.

Moisture barrier reinforcement Polyporus umbellatus (mushroom) extract works alongside pantothenic acid (vitamin B5) to strengthen the skin's natural barrier, reduce transepidermal water loss, and protect against the environmental stressors that trigger sensitivity.

Visible reduction in redness and inflammation Three bioactive compounds derived from centella asiatica, asiaticoside, asiatic acid, and madecassic acid, work together to calm active inflammation, reduce redness, and support the skin's natural healing process.

Instant cooling relief Menthol provides a cooling effect the moment the serum touches skin, soothing reactive, overheated, or sun-exposed skin and easing visible discomfort without causing irritation at its formulated concentration.

Accelerated skin recovery Pantothenic acid (vitamin B5) supports cellular repair and healing, making this serum especially effective after chemical peels, microneedling, laser treatments, or any procedure that leaves skin sensitized.

Acne Safe

iS Clinical Hydra-Cool Serum

A cooling, lightweight serum that calms redness, restores hydration, and repairs a compromised skin barrier for sensitive or reactive skin.
4.9
Rated 4.9 out of 5 stars
16 Reviews
Regular price $70.00
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Primary Concerns:

  • Compromised Barrier
  • Dehydration
  • Oil Balancing
  • Inflammation
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Best For:

  • Combination
  • Dry
  • Normal
  • Oily
  • Sensitive

iS Clinical Hydra-Cool Serum

The iS Clinical Hydra-Cool Serum is a lightweight, fast-absorbing serum designed to deliver immediate hydration, visible calming of redness, and long-term moisture barrier repair for sensitive, reactive, or post-procedure skin. It features a noticeable cooling sensation from menthol that provides instant relief on contact, making it one of the few hydrating serums that addresses both acute skin discomfort and the underlying causes of barrier compromise. The formula is fragrance-free aside from the functional menthol and free of parabens.

Key Benefits

Immediate, deep hydration Sodium hyaluronate draws moisture into the skin and binds up to 1,000 times its weight in water, quickly relieving tightness and dehydration while plumping the look of the skin.

Moisture barrier reinforcement Polyporus umbellatus (mushroom) extract works alongside pantothenic acid (vitamin B5) to strengthen the skin's natural barrier, reduce transepidermal water loss, and protect against the environmental stressors that trigger sensitivity.

Visible reduction in redness and inflammation Three bioactive compounds derived from centella asiatica, asiaticoside, asiatic acid, and madecassic acid, work together to calm active inflammation, reduce redness, and support the skin's natural healing process.

Instant cooling relief Menthol provides a cooling effect the moment the serum touches skin, soothing reactive, overheated, or sun-exposed skin and easing visible discomfort without causing irritation at its formulated concentration.

Accelerated skin recovery Pantothenic acid (vitamin B5) supports cellular repair and healing, making this serum especially effective after chemical peels, microneedling, laser treatments, or any procedure that leaves skin sensitized.

iS Clinical Hydra-Cool Serum

4.9
Rated 4.9 out of 5 stars
Based on 16 reviews
Total 5 star reviews: 14 Total 4 star reviews: 2 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
16 reviews
  • GT
    Ginger T.
    Verified Buyer
    Reviewing
    iS Clinical Hydra-Cool Serum
    I recommend this product
    How old are you? 30-39
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Blemish-prone, Oiliness
    Rated 4 out of 5 stars
    10 months ago
    Great, lightweight hydrating serum

    I love the cooling effect of this serum and how it helps with redness/irritation. I pair it with a hydrating spray and find that to be the perfect combination for me

  • JJ
    Jessica J.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Hydra-Cool Serum
    I recommend this product
    How old are you? 18-29
    What are your skin concerns? Blemish-prone
    Rated 5 out of 5 stars
    2 years ago
    iS Clinical Hydra-Cool Serum

    LOVE

    I LOVE this product! One of my absolute favorite staple products for hydration!

  • SP
    Shaila P.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Hydra-Cool Serum
    I recommend this product
    How old are you? 18-29
    What are your skin concerns? Blemish-prone
    Rated 5 out of 5 stars
    2 years ago
    iS Clinical Hydra-Cool Serum

    Best Product for my Acne Prone Skin

    I absolutely love the cooling minty feeling this product gives my skin. It provides excellent hydration in addition to my daily moisturizer. When I don't use it, my skin dries out quickly but this product helps maintain that extra layer of moisture that my skin needs to thrive.

  • KB
    Kasey B.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Hydra-Cool Serum
    I recommend this product
    How old are you? 40-49
    Rated 5 out of 5 stars
    3 years ago
    iS Clinical Hydra-Cool Serum

    My teenager loves this product!

    My teenager loves this product! She says she likes it bc it has a fast drying time.

  • JV
    Jacky V.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Hydra-Cool Serum
    I recommend this product
    How old are you? 18-29
    What are your skin concerns? Blemish-prone
    Rated 5 out of 5 stars
    3 years ago
    iS Clinical Hydra-Cool Serum .5oz

    Feels nice on skin

    I have struggled with my skin for years. I have skin prone to clogging and is very sensitive to products. Hence this serum feels sooo good on my skin, no sticky residue or irritation. I'm healing my skin and this is helping so much.