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iS Clinical Super Serum Advance+

iS Clinical Super Serum Advance+ is a professional-grade treatment serum that combines ascorbic acid, peptides, and targeted botanicals to address some of the most persistent skin concerns: discoloration, scarring, stretch marks, uneven texture, and early signs of aging. It absorbs quickly without a heavy feel and is formulated to be effective at twice-daily use without causing irritation. Note that because this formula relies on natural botanical extracts, slight color variation between batches is completely normal and does not affect performance.

Key Benefits

Fades dark spots and discoloration Ascorbic acid and arbutin work in tandem to reduce the appearance of post-acne marks, sun damage, and uneven pigmentation across the face, neck, and chest.

Visibly improves raised scars and stretch marks Tripeptide-1 supports collagen synthesis and tissue regeneration, gradually smoothing the texture of scarring and stretch marks with consistent use.

Soothes irritation and supports barrier resilience Polyporus umbellatus (mushroom) extract and calcium pantothenate (vitamin B5) calm redness, reduce inflammation, and reinforce the skin's moisture barrier.

Protects against environmental damage Ascorbic acid neutralizes free radicals caused by UV exposure and pollution, helping to prevent oxidative stress that leads to premature aging.

Plumps and smooths the look of fine lines Hyaluronic acid and tripeptide-1 work together to hydrate and support skin structure, visibly reducing the appearance of early lines over time.

Acne Safe

iS Clinical Super Serum Advance+

A vitamin C serum that fades dark spots, improves raised scars and stretch marks, and protects against environmental damage for visibly clearer skin.
4.6
Rated 4.6 out of 5 stars
14 Reviews
Regular price $104.00
Unit price
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Primary Concerns:

  • Dullness
  • Fine Lines
  • Loss of Firmness
  • Pigmentation
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Best For:

  • Combination
  • Dry
  • Normal
  • Oily

iS Clinical Super Serum Advance+

iS Clinical Super Serum Advance+ is a professional-grade treatment serum that combines ascorbic acid, peptides, and targeted botanicals to address some of the most persistent skin concerns: discoloration, scarring, stretch marks, uneven texture, and early signs of aging. It absorbs quickly without a heavy feel and is formulated to be effective at twice-daily use without causing irritation. Note that because this formula relies on natural botanical extracts, slight color variation between batches is completely normal and does not affect performance.

Key Benefits

Fades dark spots and discoloration Ascorbic acid and arbutin work in tandem to reduce the appearance of post-acne marks, sun damage, and uneven pigmentation across the face, neck, and chest.

Visibly improves raised scars and stretch marks Tripeptide-1 supports collagen synthesis and tissue regeneration, gradually smoothing the texture of scarring and stretch marks with consistent use.

Soothes irritation and supports barrier resilience Polyporus umbellatus (mushroom) extract and calcium pantothenate (vitamin B5) calm redness, reduce inflammation, and reinforce the skin's moisture barrier.

Protects against environmental damage Ascorbic acid neutralizes free radicals caused by UV exposure and pollution, helping to prevent oxidative stress that leads to premature aging.

Plumps and smooths the look of fine lines Hyaluronic acid and tripeptide-1 work together to hydrate and support skin structure, visibly reducing the appearance of early lines over time.

iS Clinical Super Serum Advance+

4.6
Rated 4.6 out of 5 stars
Based on 14 reviews
Total 5 star reviews: 9 Total 4 star reviews: 4 Total 3 star reviews: 1 Total 2 star reviews: 0 Total 1 star reviews: 0
Customers Talked About
14 reviews
  • SB
    Shelley B.
    Verified Buyer
    Reviewing
    iS Clinical Super Serum Advance+
    I recommend this product
    How old are you? 50-65
    What is your skin type? Normal
    What is your skin tone? Medium
    What are your skin concerns? Ageing
    Rated 5 out of 5 stars
    5 months ago
    Is Clinical Super Serum Advance

    My fav IS Clinical Serum. I can feel it working on my skin as soon as I apply.

  • J
    Jells
    Verified Reviewer
    Reviewing
    iS Clinical Super Serum Advance+
    How old are you? 40-49
    What is your skin type? Combination
    What is your skin tone? Medium
    What are your skin concerns? Ageing, Blemish-prone, Wrinkles, Sun Damage, Sensitivity
    Rated 3 out of 5 stars
    9 months ago
    No breakouts

    My esti recommended this to me, I did not realize it had vitamin C or would not have bought it because most vitamin C breaks me out. This serum is also thicker which my skin has never tolerated serums very well. This did not clog my pores or cause breakouts which was surprising but it did seem to leave me with a little redness so maybe it is too strong for me. It is also very pricey for how long it lasts, I am very minimal with how much I applied because I was nervous about breakouts with the thickness of it. If you’re not concerned with price and looking for a good product with Vitamin C it is worth trying though but I have not yet repurchased and will try something else for now.

  • SA
    Stacy A.
    Verified Buyer
    Reviewing
    iS Clinical Super Serum Advance+
    I recommend this product
    How old are you? 50-65
    What is your skin type? Dry
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Pigmentation, Wrinkles, Dryness
    Rated 5 out of 5 stars
    9 months ago
    Great Vitamin C+ Seum

    I love how I just need a few drops daily for this superhero to nourish my skin. I put it on after my toner and give it a minute to soak in before I moisturize. It’s the rock star in my routine, because I use such a small amount it lasts for months so actually not as pricey as it seems.

  • MV
    Melissa V.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Super Serum Advance+
    I recommend this product
    How old are you? 50-65
    Rated 5 out of 5 stars
    2 years ago
    iS Clinical Super Serum Advance+

    Potent

    My skin loves all things iS Clinical! And this serum is no exception. A potent serum that absorbs quickly and penetrates deeply. Don't let the watery consistency fool you. This serum gets to work quickly improving skin tone and texture. On my first bottle and loving the results thus far.

  • JA
    Joseph A.
    Flag of United States
    Verified Buyer
    Reviewing
    iS Clinical Super Serum Advance+
    I recommend this product
    How old are you? 30-39
    Rated 5 out of 5 stars
    3 years ago
    iS Clinical Super Serum Advance+

    Powerful

    I layer this under my iS Clinical Pro Youth Body Complex. Really good. It is expensive but you get what you pay for.