NeoGenesis Barrier Renewal Cream

The NeoGenesis Barrier Renewal Cream is a moisturizer booster designed to lock in hydration and strengthen the skin barrier, preventing transepidermal water loss (TEWL). Formulated with the perfect balance of ceramides and cholesterol-free fatty acids, this lightweight yet powerful finishing layer helps seal in moisture for long-lasting hydration and improved skin resilience.

Designed to be used over your favorite hydrating moisturizer, this barrier-fortifying cream is ideal for dry, sensitive, rosacea-prone, and compromised skin. With regular use, it supports skin repair, reduces irritation, and enhances firmness, making it a must-have for moisture retention and overall skin health.

  • Boosts hydration retention by sealing in moisture
  • Strengthens and repairs the skin barrier to prevent moisture loss
  • Provides essential ceramides and lipids for long-term resilience
  • Lightweight, non-greasy formula, perfect as a finishing layer
  • Unscented and oncology-approved, safe for even the most sensitive skin

30 mL | Airless Pump

120 mL or 5 mL | Pump

Acne Safe

NeoGenesis Barrier Renewal Cream

NeoGenesis Barrier Renewal Cream – The Ultimate Moisture Lock Booster

4.8
Rated 4.8 out of 5 stars
236 Reviews
Regular price $52.00
Unit price
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Primary Concerns:

  • Compromised Barrier
  • Dehydration
  • Dryness
  • Dullness
  • Redness/Rosacea
Lotion bottle icons

Best For:

  • Dry
  • Normal
  • Sensitive

NeoGenesis Barrier Renewal Cream

The NeoGenesis Barrier Renewal Cream is a moisturizer booster designed to lock in hydration and strengthen the skin barrier, preventing transepidermal water loss (TEWL). Formulated with the perfect balance of ceramides and cholesterol-free fatty acids, this lightweight yet powerful finishing layer helps seal in moisture for long-lasting hydration and improved skin resilience.

Designed to be used over your favorite hydrating moisturizer, this barrier-fortifying cream is ideal for dry, sensitive, rosacea-prone, and compromised skin. With regular use, it supports skin repair, reduces irritation, and enhances firmness, making it a must-have for moisture retention and overall skin health.

  • Boosts hydration retention by sealing in moisture
  • Strengthens and repairs the skin barrier to prevent moisture loss
  • Provides essential ceramides and lipids for long-term resilience
  • Lightweight, non-greasy formula, perfect as a finishing layer
  • Unscented and oncology-approved, safe for even the most sensitive skin

30 mL | Airless Pump

120 mL or 5 mL | Pump

NeoGenesis Barrier Renewal Cream

4.8
Rated 4.8 out of 5 stars
Based on 236 reviews
Total 5 star reviews: 204 Total 4 star reviews: 21 Total 3 star reviews: 11 Total 2 star reviews: 0 Total 1 star reviews: 0
Reviews Summary
Customers say this cream provides excellent hydration while maintaining a lightweight feel. Many reviews mention its effectiveness for dry skin without causing breakouts. The cream absorbs quickly and works well for both day and night use. While some note it's particularly beneficial during winter months, others find it suitable year-round. Reviews frequently highlight its gentle nature on sensitive skin and its ability to layer well with other products. Though most praise its moisturizing qualities, some mention the high price point as a concern. Common feedback includes its smooth texture and non-greasy finish. Several users appreciate how it helps maintain skin moisture throughout the day.
236 reviews
  • MD
    Mariah D.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 30-39
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Acne, Ageing, Pigmentation, Wrinkles, Sensitivity
    Rated 5 out of 5 stars
    2 days ago
    Great cream

    Moisturizing and gentle. Love NeoGenesis for their effective and fragrance free formulas.

  • AW
    Amanda W.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 40-49
    What is your skin type? Dry
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Dryness
    Rated 5 out of 5 stars
    1 week ago
    Really Works!

    This will be my new winter go to when the cold and wind break down my skin barrier. It has truly saved my skin this winter.

  • DC
    Danielle C.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 40-49
    What is your skin type? Dry
    What is your skin tone? Fair
    What are your skin concerns? Acne, Ageing, Blemish-prone, Dryness, Wrinkles
    Rated 4 out of 5 stars
    1 week ago
    Great for Healing

    I used this Barrier Renewal Cream while healing from a BBL/Moxi treatment. It really made my skin feel comfortable and not tight feeling. The reason for 4 stars is I am not sure if it contributed to some breakouts I had around my nose and upper lip. It could be because of the laser or the cream but I am very acne prone with dry skin.

  • MB
    MaryAnn B.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 50-65
    What is your skin type? Dry
    What is your skin tone? Medium
    What are your skin concerns? Ageing, Sensitivity, Dryness
    Rated 5 out of 5 stars
    2 weeks ago
    Great moisturizer!

    lightweight and luxe moisturizer which keeps my dry skin hydrated all day. This has been my go to moisturizer!

  • KU
    Karen U.
    Verified Buyer
    Reviewing
    NeoGenesis Barrier Renewal Cream
    I recommend this product
    How old are you? 50-65
    What is your skin type? Combination
    What is your skin tone? Fair
    What are your skin concerns? Ageing, Pigmentation, Wrinkles, Sun Damage
    Rated 5 out of 5 stars
    2 months ago
    Very Nice

    This is a great daytime moisturizer. I use it on before my sun screen.