( plated )™ Skin Science INTENSE Serum
( plated )™ Skin Science INTENSE Serum is the most concentrated formula in the plated lineup — a clinical-grade regenerative serum powered by Renewosome™ technology that works at the cellular level to visibly reduce fine lines, wrinkles, hyperpigmentation, and loss of firmness. Each pump delivers over 15 billion platelet-derived exosomes that function as molecular messengers, activating the skin's natural repair pathways to accelerate renewal from the inside out. It is the highest-performing option in the (plated)™ range and the formula of choice for those who want measurable, visible results.
Key Benefits
Renewosome™ Exosome Technology — delivers over 15 billion platelet-derived exosomes per pump to stimulate cellular communication and activate the skin's natural regeneration pathways for accelerated, visible renewal.
Reduces Fine Lines and Wrinkles — exosome signaling encourages skin cells to repair and rebuild structural proteins, visibly smoothing expression lines and deep wrinkles with consistent daily use.
Improves Tone and Hyperpigmentation — supports healthy cellular turnover and reduces oxidative stress to diminish dark spots, post-inflammatory discoloration, and uneven tone over time.
Firms and Restores Elasticity — promotes the production of structural proteins that give skin its bounce and resilience, visibly improving firmness and the appearance of lifted, more youthful skin.
Reduces Inflammation and Redness — platelet-derived exosomes act as molecular first responders that calm active inflammation and visibly reduce redness associated with oxidative stress and skin aging.
Antioxidant Defense — neutralizes environmental and oxidative stressors that are among the primary drivers of accelerated cellular aging, dullness, and compromised skin health.
INTENSE Serum is designed for anyone with more advanced or persistent skin concerns who wants the most concentrated regenerative formula available. If fine lines, wrinkles, hyperpigmentation, or loss of firmness are your primary concerns, this is the formula built specifically for you. It is the flagship product in the (plated)™ lineup, delivering over 15 billion platelet-derived exosomes per pump for accelerated, visible results that conventional serums cannot match.
It is equally well suited for anyone who wants a high-performance daily serum backed by clinical-grade biotechnology rather than conventional skincare ingredients. Whether you are in your late 30s and noticing the earliest signs of aging or navigating more significant skin changes later in life, INTENSE Serum meets you where your skin is and works at the cellular level to address aging at the source.
It is also the right choice for those who have used skincare consistently without achieving the visible results they were expecting. Because Renewosome™ technology targets cellular regeneration rather than the surface, it is a meaningful upgrade for skin that has plateaued with conventional serums and treatments and is ready for a genuinely different approach.
The highest exosome concentration in the lineup makes INTENSE the go-to formula when results matter most. Pair it with an enzyme exfoliant at least three times per week to clear dead skin cells and open the surface for deeper absorption — the difference in how quickly visible results appear is significant. INTENSE can also be used as a dedicated six-week intensive protocol before transitioning to (plated)™ DAILY Serum for long-term maintenance, which is an approach we recommend for clients tackling more established skin concerns.
Prepare: Start with clean, dry skin. Cleanse, tone, and ensure your face is completely dry before applying to maximize serum absorption.
Apply: Dispense 1 pump into your palm and apply evenly across the full face. For neck and chest coverage, dispense an additional pump and smooth downward.
Technique: Press and pat the serum into the skin rather than rubbing. Avoid the eye area. Allow to fully absorb before layering additional products.
Frequency: Use once or twice daily as the very first active step in your skincare routine. In the morning, always follow with a broad-spectrum SPF. Each bottle provides approximately 64 pumps.
NOTE: When replacing the refill, don't lose the silver ring. Watch this video learn how to properly use the refill.
- Platelet-Derived Exosomes: Utilizing the power of the body’s natural first responders, these exosomes deliver targeted peptides and antioxidants directly to the site of need for the ultimate skin renewal. They play a pivotal role in the skin’s natural regeneration process, improving tone, texture, firmness, and elasticity for a healthier, more youthful complexion.
- Panthenol (Vitamin B5): A powerful natural moisturizer, healer, and protector that rebuilds the barrier and acts as a shield against irritation.
- Glycerin: Provides long-lasting, intense moisture retention.
- Hyaluronic Acid: Naturally occurring in the skin, provides intense hydration and plumps and improves skin barrier function by attracting and retaining moisture.
- Arginine: An essential amino acid that supports collagen production and skin repair. Arginine helps improve firmness and elasticity while boosting hydration and strengthening the skin barrier.
Purified Water, Glycerin, Pentylene Glycol, Panthenol, Human Platelet Extract*, Polyacrylate Crosspolymer-6, Hyaluronic Acid, Caprylyl Glycol, 1,2-Hexanediol, Hydrolyzed Gelatin, Arginine, Silanetriol
*( plated )™️ Skin Science is made in labs in Rochester, MN, and derived human platelets safely and ethically from compliant blood banks in the United States to incorporate into our proprietary manufacturing process, which ensures a formulation with high levels of purity and consistency from batch to batch.
What are platelet-derived exosomes and how do they work?
Exosomes are naturally occurring nano-sized vesicles that act as molecular messengers between cells. (plated)™ Renewosome™ technology harnesses platelet-derived exosomes to deliver targeted peptides, growth factors, and antioxidants directly into the skin — activating the body's natural regeneration pathways to repair, renew, and restore a more youthful complexion.
How is INTENSE Serum different from DAILY Serum?
INTENSE Serum contains the highest concentration of Renewosome™ exosomes in the (plated)™ lineup — delivering over 15 billion exosomes per pump compared to 7.5 billion in the DAILY formula. It is designed for those targeting more advanced aging concerns or who want the fastest possible regenerative results. DAILY Serum is a hydrating daily-maintenance formula ideal for sustaining results long term.
How long does it take to see results?
Most users begin to see visible improvements in tone, texture, and radiance within four to six weeks of consistent daily use. For best results, use daily and incorporate regular enzyme exfoliation to maximize serum absorption and accelerate cellular turnover.
Can I use INTENSE Serum with retinol or other active ingredients?
Yes. INTENSE Serum is safe to use alongside retinol, vitamin C, niacinamide, and other active ingredients. Apply INTENSE as the very first step after cleansing and toning — before any other serums, treatments, or moisturizers — to ensure the exosomes reach fresh skin for maximum effectiveness.
Is INTENSE Serum suitable for sensitive skin?
Yes. The formula is free of known irritants and has been developed to be well-tolerated across skin types. If you have highly reactive skin, introduce the product once daily and monitor your skin's response before increasing to twice daily use.
How many pumps are in a bottle and how long will it last?
Each 0.5 oz bottle contains approximately 64 pumps. Using 1 to 2 pumps per application, a single bottle typically lasts four to six weeks with twice-daily use.
What is Renewosome™ technology?
Renewosome™ is (plated)™ Skin Science's proprietary exosome delivery system, featuring ethically sourced platelet-derived exosomes clinically designed to stimulate cellular communication, reduce oxidative stress, and accelerate the skin's natural regeneration cycle. It is the foundation of every product in the (plated)™ lineup.
Why buy (plated)™ INTENSE Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of (plated)™ Skin Science, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if this product is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
( plated )™ Skin Science INTENSE Serum is a clinical-grade regenerative serum powered by 15+ billion platelet-derived exosomes per pump to visibly reduce fine lines and wrinkles and improve skin tone and firmness.
- Unit price
- /per
Primary Concerns:
- Fine Lines
- Wrinkles
- Redness/Rosacea
- Loss of Firmness
- Acne Scarring
Best For:
- Dry
- Normal
- Oily
- Combination
- Sensitive
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( plated )™ Skin Science INTENSE Serum
( plated )™ Skin Science INTENSE Serum is the most concentrated formula in the plated lineup — a clinical-grade regenerative serum powered by Renewosome™ technology that works at the cellular level to visibly reduce fine lines, wrinkles, hyperpigmentation, and loss of firmness. Each pump delivers over 15 billion platelet-derived exosomes that function as molecular messengers, activating the skin's natural repair pathways to accelerate renewal from the inside out. It is the highest-performing option in the (plated)™ range and the formula of choice for those who want measurable, visible results.
Key Benefits
Renewosome™ Exosome Technology — delivers over 15 billion platelet-derived exosomes per pump to stimulate cellular communication and activate the skin's natural regeneration pathways for accelerated, visible renewal.
Reduces Fine Lines and Wrinkles — exosome signaling encourages skin cells to repair and rebuild structural proteins, visibly smoothing expression lines and deep wrinkles with consistent daily use.
Improves Tone and Hyperpigmentation — supports healthy cellular turnover and reduces oxidative stress to diminish dark spots, post-inflammatory discoloration, and uneven tone over time.
Firms and Restores Elasticity — promotes the production of structural proteins that give skin its bounce and resilience, visibly improving firmness and the appearance of lifted, more youthful skin.
Reduces Inflammation and Redness — platelet-derived exosomes act as molecular first responders that calm active inflammation and visibly reduce redness associated with oxidative stress and skin aging.
Antioxidant Defense — neutralizes environmental and oxidative stressors that are among the primary drivers of accelerated cellular aging, dullness, and compromised skin health.
INTENSE Serum is designed for anyone with more advanced or persistent skin concerns who wants the most concentrated regenerative formula available. If fine lines, wrinkles, hyperpigmentation, or loss of firmness are your primary concerns, this is the formula built specifically for you. It is the flagship product in the (plated)™ lineup, delivering over 15 billion platelet-derived exosomes per pump for accelerated, visible results that conventional serums cannot match.
It is equally well suited for anyone who wants a high-performance daily serum backed by clinical-grade biotechnology rather than conventional skincare ingredients. Whether you are in your late 30s and noticing the earliest signs of aging or navigating more significant skin changes later in life, INTENSE Serum meets you where your skin is and works at the cellular level to address aging at the source.
It is also the right choice for those who have used skincare consistently without achieving the visible results they were expecting. Because Renewosome™ technology targets cellular regeneration rather than the surface, it is a meaningful upgrade for skin that has plateaued with conventional serums and treatments and is ready for a genuinely different approach.
The highest exosome concentration in the lineup makes INTENSE the go-to formula when results matter most. Pair it with an enzyme exfoliant at least three times per week to clear dead skin cells and open the surface for deeper absorption — the difference in how quickly visible results appear is significant. INTENSE can also be used as a dedicated six-week intensive protocol before transitioning to (plated)™ DAILY Serum for long-term maintenance, which is an approach we recommend for clients tackling more established skin concerns.
Prepare: Start with clean, dry skin. Cleanse, tone, and ensure your face is completely dry before applying to maximize serum absorption.
Apply: Dispense 1 pump into your palm and apply evenly across the full face. For neck and chest coverage, dispense an additional pump and smooth downward.
Technique: Press and pat the serum into the skin rather than rubbing. Avoid the eye area. Allow to fully absorb before layering additional products.
Frequency: Use once or twice daily as the very first active step in your skincare routine. In the morning, always follow with a broad-spectrum SPF. Each bottle provides approximately 64 pumps.
NOTE: When replacing the refill, don't lose the silver ring. Watch this video learn how to properly use the refill.
- Platelet-Derived Exosomes: Utilizing the power of the body’s natural first responders, these exosomes deliver targeted peptides and antioxidants directly to the site of need for the ultimate skin renewal. They play a pivotal role in the skin’s natural regeneration process, improving tone, texture, firmness, and elasticity for a healthier, more youthful complexion.
- Panthenol (Vitamin B5): A powerful natural moisturizer, healer, and protector that rebuilds the barrier and acts as a shield against irritation.
- Glycerin: Provides long-lasting, intense moisture retention.
- Hyaluronic Acid: Naturally occurring in the skin, provides intense hydration and plumps and improves skin barrier function by attracting and retaining moisture.
- Arginine: An essential amino acid that supports collagen production and skin repair. Arginine helps improve firmness and elasticity while boosting hydration and strengthening the skin barrier.
Purified Water, Glycerin, Pentylene Glycol, Panthenol, Human Platelet Extract*, Polyacrylate Crosspolymer-6, Hyaluronic Acid, Caprylyl Glycol, 1,2-Hexanediol, Hydrolyzed Gelatin, Arginine, Silanetriol
*( plated )™️ Skin Science is made in labs in Rochester, MN, and derived human platelets safely and ethically from compliant blood banks in the United States to incorporate into our proprietary manufacturing process, which ensures a formulation with high levels of purity and consistency from batch to batch.
What are platelet-derived exosomes and how do they work?
Exosomes are naturally occurring nano-sized vesicles that act as molecular messengers between cells. (plated)™ Renewosome™ technology harnesses platelet-derived exosomes to deliver targeted peptides, growth factors, and antioxidants directly into the skin — activating the body's natural regeneration pathways to repair, renew, and restore a more youthful complexion.
How is INTENSE Serum different from DAILY Serum?
INTENSE Serum contains the highest concentration of Renewosome™ exosomes in the (plated)™ lineup — delivering over 15 billion exosomes per pump compared to 7.5 billion in the DAILY formula. It is designed for those targeting more advanced aging concerns or who want the fastest possible regenerative results. DAILY Serum is a hydrating daily-maintenance formula ideal for sustaining results long term.
How long does it take to see results?
Most users begin to see visible improvements in tone, texture, and radiance within four to six weeks of consistent daily use. For best results, use daily and incorporate regular enzyme exfoliation to maximize serum absorption and accelerate cellular turnover.
Can I use INTENSE Serum with retinol or other active ingredients?
Yes. INTENSE Serum is safe to use alongside retinol, vitamin C, niacinamide, and other active ingredients. Apply INTENSE as the very first step after cleansing and toning — before any other serums, treatments, or moisturizers — to ensure the exosomes reach fresh skin for maximum effectiveness.
Is INTENSE Serum suitable for sensitive skin?
Yes. The formula is free of known irritants and has been developed to be well-tolerated across skin types. If you have highly reactive skin, introduce the product once daily and monitor your skin's response before increasing to twice daily use.
How many pumps are in a bottle and how long will it last?
Each 0.5 oz bottle contains approximately 64 pumps. Using 1 to 2 pumps per application, a single bottle typically lasts four to six weeks with twice-daily use.
What is Renewosome™ technology?
Renewosome™ is (plated)™ Skin Science's proprietary exosome delivery system, featuring ethically sourced platelet-derived exosomes clinically designed to stimulate cellular communication, reduce oxidative stress, and accelerate the skin's natural regeneration cycle. It is the foundation of every product in the (plated)™ lineup.
Why buy (plated)™ INTENSE Serum from Art of Skin Care?
Art of Skin Care is an authorized retailer of (plated)™ Skin Science, so every product you receive is 100% authentic, sourced directly through official brand channels and never from third-party resellers. Our team is made up of licensed, acne-certified estheticians who hand-select the products we carry based on real skin science and professional results. We don't just sell skincare; we understand it. Not sure if this product is right for your skin? Get a free skincare consultation and one of our estheticians will personally guide you.
Clinical Results in 6 Weeks
- Reduce the look of fine lines and wrinkles
- Even the appearance of dark spots and redness
- Enhance luminosity and glow
- Gentle for all skin types
Explore More Recommendations
( plated )™ Skin Science INTENSE Serum
- SCSteven C.Verified BuyerReviewing( plated )™ Skin Science INTENSE SerumI recommend this productHow old are you? 50-65What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Ageing, Sun Damage, WrinklesRated 5 out of 5 stars1 week agoGreat product
I’ve been using this product for over a year and have seen my skin taken incredible turn for the better.
Was this helpful? - PCPaula C.Verified BuyerReviewing( plated )™ Skin Science INTENSE SerumI recommend this productHow old are you? 50-65What is your skin type? DryWhat is your skin tone? FairWhat are your skin concerns? Ageing, Redness, Dryness, WrinklesRated 5 out of 5 stars1 week agoAmazing serum
This serum is truly amazing! I was hesitant to purchase it because of the price, but it is worth it! My skin looks so much healthier and smoother plumper). I would certainly recommend giving it a try, and it does last quite a while since just a drop provides enough for my entire face. It is cutting edge technology!! Check it out on AOSC!!!
Was this helpful? - LNLori N.Verified BuyerReviewing( plated )™ Skin Science INTENSE SerumI recommend this productHow old are you? 50-65What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? Blemish-prone, Ageing, Sun Damage, WrinklesRated 5 out of 5 stars2 weeks agoFirst bottle works great!
So i misread the instructions and used this for much longer than recommended. At one point I stopped to save up for the next bottle …. What i noticed was after using the first bottle I noticed a big difference in how my skin looked but then nothing after that. Then after the break, I started again and same thing.. noticed a difference after the first bottle and then nothing after that. All to say, I think it is definitely pricy, but imo just one bottle is needed to make your skin look great :)
Was this helpful? - AMAudrey M.Verified BuyerReviewing( plated )™ Skin Science INTENSE SerumI recommend this productHow old are you? 30-39What is your skin type? CombinationWhat is your skin tone? MediumWhat are your skin concerns? PigmentationRated 5 out of 5 stars3 weeks agoReplaced my neogenesis
Pricey ouch. Does it help, I think so? Does seem to help heal my skin quicker. Time will tell. I replaced using neogenesis serum with this one.
Was this helpful? - CWCarmen W.Verified BuyerReviewing( plated )™ Skin Science INTENSE SerumI recommend this productHow old are you? 50-65What is your skin type? NormalWhat is your skin tone? MediumWhat are your skin concerns? Ageing, Pigmentation, Dryness, Sensitivity, WrinklesRated 5 out of 5 stars2 months agoPlayed Intense Serum
I hesitated trying this product for over a year. The price kept me from trying this amazing serum. I have noticed a difference in my skin after only using it for 2 weeks. It feels firmer, brighter, and more hydrated. I treated myself this year and I’m very happy I did!
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