Rhonda Allison Bio 53 Matrix Plus
Same Formula as Growth Factor Serum Plus and Cell Renewal Serum
Those on prescription-strength topicals like tretinoin or for individuals preparing for more corrective/advanced treatments, this serum lends healing and anti inflammatory support.
- Extra Strengthening Support
- Potent Epidermal Growth Factor
- Powerful Antioxidants
- Renews and Fortifies Skin
- Reduces Inflammation
- Healthy Cellular Growth
- Cooling, Soothing Sensation
0.5 oz or 1.7 oz
We love to partner with the skin-strengthening benefits of Mandelic Rejuvenator.
Dispense 1-2 pumps onto fingertips and gently massage into clean, dry skin or under your favorite RA moisturizer.
- EGF (proprietary formula): Epidermal growth factor targets damaged, inflamed and mature skin to promote skin renewal and healing.
- Sodium Chondroitin Sulfate (Bovine Soluble Trachea Powder): A naturally occurring mucopolysaccharide found in connective tissue, including skin, this potent ingredient reinforces the intercellular matrix within the skin while reducing inflammation; strengthens and soothes skin, increases hydration and promotes healing.
- Squalane: Keeps skin hydrated and balances oil production by mimicking the skin’s acid mantle while also reducing inflammation, soothing skin irritation, and improving elasticity.
- Phenyl-t-Butylnitrone (Spin Trap): An intelligent and powerful antioxidant compound that targets and traps free radicals to convert them into useful oxygen, and transports back into the respiratory cycle.
- Bisabolol: Skin-soothing agent with anti-inflammatory and antimicrobial properties.
- Crocus Chrysanthus Bulb Extract: Helps improve cellular communication, renews skin’s resilience, and rejuvenates texture.
Aqua (Water), Glycerin, Propylene Glycol, Squalane, Chlorophyll, rh-Oligopeptide-1 (EGF), Sodium Chondroitin Sulfate, Carbomer, Benzyl Alcohol, Leuconostoc/Radish Root Ferment Filtrate, Acacia Senegal Gum, Sodium Hydroxide, Ricinus Communis (Castor) Seed Oil, Allantoin, Sodium Gluconate, Caprylhydroxamic Acid, Bisabolol (L-alpha), Glycyrrhiza Glabra (Licorice), Rhizome/Root Extract, Glucuronolactone (D), Phospholipids, Aloe Barbadensis Leaf Juice Powder, Camellia Oleifera (Green Tea) Leaf Extract, Hamamelis Virginiana (Witch Hazel) Water, Citric Acid,Crocus Chrysanthus Bulb Extract, Alcohol Denat., Fullerene, Xanthan Gum, Fragrance/Parfum, Mentha Piperita (Peppermint) Oil
Rhonda Allison Bio 53 Matrix Plus is a potent pro-youth serum enriched with epidermal growth factor and the additional rejuvenating, skin-strengthening benefits of chondroitin, this elegant, lightweight, cooling serum nourishes and soothes depleted skin.
- Unit price
- /per

Primary Concerns:
- Wrinkles
- Fine Lines
- Loss of Firmness

Best For:
- Dry
- Normal
- Oily
- Combination
- Sensitive
Adding product to your cart
Rhonda Allison Bio 53 Matrix Plus
Same Formula as Growth Factor Serum Plus and Cell Renewal Serum
Those on prescription-strength topicals like tretinoin or for individuals preparing for more corrective/advanced treatments, this serum lends healing and anti inflammatory support.
- Extra Strengthening Support
- Potent Epidermal Growth Factor
- Powerful Antioxidants
- Renews and Fortifies Skin
- Reduces Inflammation
- Healthy Cellular Growth
- Cooling, Soothing Sensation
0.5 oz or 1.7 oz
We love to partner with the skin-strengthening benefits of Mandelic Rejuvenator.
Dispense 1-2 pumps onto fingertips and gently massage into clean, dry skin or under your favorite RA moisturizer.
- EGF (proprietary formula): Epidermal growth factor targets damaged, inflamed and mature skin to promote skin renewal and healing.
- Sodium Chondroitin Sulfate (Bovine Soluble Trachea Powder): A naturally occurring mucopolysaccharide found in connective tissue, including skin, this potent ingredient reinforces the intercellular matrix within the skin while reducing inflammation; strengthens and soothes skin, increases hydration and promotes healing.
- Squalane: Keeps skin hydrated and balances oil production by mimicking the skin’s acid mantle while also reducing inflammation, soothing skin irritation, and improving elasticity.
- Phenyl-t-Butylnitrone (Spin Trap): An intelligent and powerful antioxidant compound that targets and traps free radicals to convert them into useful oxygen, and transports back into the respiratory cycle.
- Bisabolol: Skin-soothing agent with anti-inflammatory and antimicrobial properties.
- Crocus Chrysanthus Bulb Extract: Helps improve cellular communication, renews skin’s resilience, and rejuvenates texture.
Aqua (Water), Glycerin, Propylene Glycol, Squalane, Chlorophyll, rh-Oligopeptide-1 (EGF), Sodium Chondroitin Sulfate, Carbomer, Benzyl Alcohol, Leuconostoc/Radish Root Ferment Filtrate, Acacia Senegal Gum, Sodium Hydroxide, Ricinus Communis (Castor) Seed Oil, Allantoin, Sodium Gluconate, Caprylhydroxamic Acid, Bisabolol (L-alpha), Glycyrrhiza Glabra (Licorice), Rhizome/Root Extract, Glucuronolactone (D), Phospholipids, Aloe Barbadensis Leaf Juice Powder, Camellia Oleifera (Green Tea) Leaf Extract, Hamamelis Virginiana (Witch Hazel) Water, Citric Acid,Crocus Chrysanthus Bulb Extract, Alcohol Denat., Fullerene, Xanthan Gum, Fragrance/Parfum, Mentha Piperita (Peppermint) Oil






Explore More Recommendations
Rhonda Allison Bio 53 Matrix Plus
- ERElizabeth R.Verified BuyerReviewingRhonda Allison Bio 53 Matrix PlusI recommend this productHow old are you? Over 65What is your skin type? DryWhat is your skin tone? MediumWhat are your skin concerns? Dryness, Wrinkles, AgeingRated 5 out of 5 stars2 months agoAmazing serum
I totally am smitten with this product. The smell and feel on my skin as it works it’s manic just is so appealing . You can not go wrong with this anti aging product !
Was this helpful? - SAStacy A.Verified BuyerReviewingRhonda Allison Bio 53 Matrix PlusI recommend this productHow old are you? 50-65Rated 5 out of 5 stars8 months agoRhonda Allison Bio 53 Matrix Plus
Great Serum
This is one of my favorite serums from RA. I alternate between DNA Reversal and this. It makes my skin feel so nourished when I put it on. I put a little (one pump) in my hands and then pat it on my face. A little goes a long way and my skin loves it.
Was this helpful? - TTamaraVerified BuyerReviewingRhonda Allison Bio 53 Matrix PlusI recommend this productHow old are you? 40-49Rated 5 out of 5 stars1 year agoRhonda Allison Bio 53 Matrix Plus
Bio 53 Matrix
I have used this product for over 6years. It has helped my skin become younger and smoother.
Was this helpful? - SStaceyVerified BuyerReviewingRhonda Allison Bio 53 Matrix PlusI recommend this productHow old are you? 40-49Rated 5 out of 5 stars1 year agoRhonda Allison Bio 53 Matrix Plus
So good for Tretinoin users
I was recommended this product by my aesthetician because my skin was so dry and flakey using tretinoin. I pair this with Drops of Essence and the pair help heal my skin so well. I buy the big bottle and it last me 3 months using AM & PM. I can usually get away with just one pump, but if my skin is feeling extra dry and flakey I'll use 2. Wears well under makeup as part of my morning routine. I have sensitive skin with rosacea and this product doesn't upset my skin or cause any flareups.
Was this helpful? - VSVirginia S.Verified BuyerReviewingRhonda Allison Bio 53 Matrix PlusI recommend this productRated 5 out of 5 stars1 year agoRhonda Allison Bio 53 Matrix Plus
Love this!
I am LOVING this product! I've been using Rhonda Allison products for several years now, and this one is one of my favorites! It firms and lifts my skin! I love my results!
Was this helpful?
Why Art of Skin Care?
At Art of Skin Care, we tailor solutions to you—no one-size-fits-all approach here. Whether tackling acne or embracing healthy aging, our expert estheticians will guide you every step of the way. More than a brand, we’re your partner in radiant, confident skin.