Skinbetter InterFuse Treatment Cream FACE & NECK is a peptide-rich moisturizing treatment that targets fine lines, wrinkles, and loss of firmness across two of the most age-revealing areas of the body. Rather than relying on hydration alone, this cream pairs a multi-peptide complex with Skinbetter's patented InterFuse delivery technology to push active ingredients deeper into the skin where they can make the most visible difference. The result is smoother, firmer-feeling skin from the forehead to the décolletage.

Key Benefits

Smooths Fine Lines on the Face and Neck A targeted blend of palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, and acetyl dipeptide-1 cetyl ester helps visibly reduce the look of fine lines in areas where thin skin and repetitive movement make wrinkles especially pronounced.

Firms and Tones Aging Neck Skin Dipeptide diaminobutyroyl benzylamide diacetate, a signal peptide that mimics the effect of Waglerin-1, helps relax the appearance of expression-related lines while supporting a more toned, less crepey look along the jawline and neck.

Hydrates Without Heaviness Squalane, glycerin, and shea butter deliver rich, lasting moisture that keeps skin comfortable and plump throughout the day without a greasy or occlusive feel.

Protects Against Environmental Aging Tocopherol (vitamin E) and olive fruit extract provide antioxidant defense against free radical damage from UV exposure and pollution, helping to slow the environmental stress that accelerates visible aging on exposed skin.

Optimizes Active Ingredient Delivery Skinbetter's patented InterFuse technology enhances how peptides and antioxidants penetrate and interact with the skin, helping actives reach the precise layers where they can do the most work.

19% Face: Improvement in smoothness at 12 weeks*

11% Face and Neck: Improvement in crepiness at 12 weeks*

Patient Satisfaction

90% agree skin appeared tightened at 12 weeks*

*A 12-week dermatologist-led clinical study in participants with mild-to-moderate laxity on the lower face and neck, moderate-to-severe fine lines and wrinkles on the face, and mild-to-moderate fine lines and wrinkles on the neck. N=52.

If fine lines are deepening around your mouth, along your jawline, or creeping down your neck, this treatment cream was built for exactly those concerns. It is especially well-suited for anyone whose neck and décolletage are aging faster than the rest of their complexion, showing crepiness, textural changes, or visible laxity.

Ideal for normal, dry, and combination skin types looking for a peptide-rich face and neck cream that consolidates two steps into one without sacrificing the potency of either. If you have been layering a separate neck cream on top of your moisturizer and want a simpler routine that still delivers targeted anti-aging results, this is the product to reach for.

When applying to the neck, tilt your chin slightly upward to smooth and extend the skin surface, then use gentle upward sweeping motions from the collarbone to the jawline. This ensures even coverage in the folds and creases where product tends to skip and where signs of aging tend to show first.

Apply: After cleansing and applying any serums or treatments, dispense an appropriate amount onto fingertips.

Technique: Gently smooth the cream across the entire face, then extend down to the neck and décolletage using light upward strokes to avoid pulling on delicate skin.

Frequency: Use morning and evening as the moisturizing step in your routine. Follow with broad-spectrum sunscreen during the day.